[中国专家关于检查点抑制剂肺炎诊断与管理的共识(2025)]。

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引用次数: 0

摘要

检查点抑制剂肺炎(CIP)是一种罕见的免疫相关不良反应,可严重影响后续的抗肿瘤免疫治疗,甚至导致呼吸衰竭或死亡。然而,如果及早发现和诊断,并及时和适当地治疗,大多数患者预后良好,有些患者可能有资格接受随后的免疫再挑战。为规范CIP患者的诊断和治疗,改善其预后,北京协和医院肺与重症医学科发起并制定了该共识,经中国抗癌协会肿瘤呼吸疾病专业委员会专家讨论并达成共识。中华医学会胸科学会肺癌分会、北京市肿瘤防治研究会。与会专家就CIP的危险因素、临床特征、诊断评价措施、诊断标准、鉴别诊断、治疗策略、康复方案等方面形成了18条专家建议,供临床医生参考。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
[Chinese experts consensus on the diagnosis and management of checkpoint inhibitor pneumonitis(2025)].

Checkpoint inhibitor pneumonitis (CIP) is a rare type of immune-related adverse reaction, that can seriously affect the subsequent anti-tumor immunotherapy and even lead to respiratory failure or death. However, if identified and diagnosed early, and treated promptly and appropriately, most patients have a good prognosis, and some may be eligible for subsequent immune rechallenge. In order to standardize diagnosis and treatment of patients with CIP and improve their prognosis, the Department of Pulmonary and Critical Care Medicine of Peking Union Medical College Hospital initiated and developed the consensus, which was discussed and reached a consensus by experts from the Oncology Respiratory Disease Committee of China Anti-Cancer Association, Lung Cancer Group of Thoracic Society of Chinese Medical Association and Beijing Cancer Prevention and Treatment Research Association. The consensus formed 18 expert recommendations on the risk factors, clinical characteristics, diagnostic evaluation measures, diagnostic criteria, differential diagnosis, treatment strategies and rehabilitation plans of CIP for clinicians' reference.

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