多模态超声评估活检证实的慢性肾病患者肾纤维化。

IF 3.1 3区 医学 Q1 ACOUSTICS
Xinyue Huang, Tianhong Wei, Jie Li, Letian Xu, Yangshuo Tang, Jin-Tang Liao, Bo Zhang
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引用次数: 0

摘要

建立结合临床资料和多模态超声的判别功能模型,预测慢性肾病(CKD)患者肾纤维化程度,探讨超声新技术在无创评估肾纤维化中的应用价值。收集CKD患者的临床资料及超声、横波弹性成像、血管平面波超敏影像特征。筛选有意义的指标,建立区分肾纤维化程度的判别功能模型,并评价诊断效果。158例患者根据病理结果分为4组。4组间或组间的显著性指标主要为年龄、肾小球滤过率、血清肌酐、肾动脉峰值收缩速度及阻力指数、肾弹性、弓状动脉血管密度(p . 539)
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Multimodal Ultrasound for Assessment of Renal Fibrosis in Biopsy-Proven Patients with Chronic Kidney Disease.

To establish a discriminant function model combining clinical data and multimodal ultrasound to predict the degree of renal fibrosis in patients with chronic kidney disease (CKD) and to explore the application value of the non-invasive assessment of renal fibrosis by new ultrasound techniques.Clinical data and ultrasonography, shear wave elastography, and angio planewave ultrasensitive imaging characteristics of patients with CKD were collected. The significant indicators were screened to establish discriminant function models to distinguish the degree of renal fibrosis, and the diagnostic efficacy was evaluated.The 158 patients were divided into 4 groups according to pathological results. The significant indicators among or within the 4 groups were mainly age, estimated glomerular filtration rate, serum creatinine, peak systolic velocity and resistance index of renal arteries, kidney elasticity, and arcuate artery vascular density (p<0.05). The discriminant function models exhibited good diagnostic efficiency and higher accuracy compared to any single indicator.The SWE elasticity value of the kidney increases with the degree of fibrosis, while AP can visualize microvascular conditions qualitatively and quantitatively. Multimodal ultrasound combined with clinical data is a non-invasive strategy for the assessment of renal fibrosis.

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来源期刊
Ultraschall in Der Medizin
Ultraschall in Der Medizin 医学-核医学
CiteScore
5.30
自引率
8.80%
发文量
228
审稿时长
6-12 weeks
期刊介绍: Ultraschall in der Medizin / European Journal of Ultrasound publishes scientific papers and contributions from a variety of disciplines on the diagnostic and therapeutic applications of ultrasound with an emphasis on clinical application. Technical papers with a physiological theme as well as the interaction between ultrasound and biological systems might also occasionally be considered for peer review and publication, provided that the translational relevance is high and the link with clinical applications is tight. The editors and the publishers reserve the right to publish selected articles online only. Authors are welcome to submit supplementary video material. Letters and comments are also accepted, promoting a vivid exchange of opinions and scientific discussions.
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