选择性冠状动脉内注射硝酸盐对类固醇和抗组胺药物治疗后造影剂诱导的I型库尼斯综合征有效。

IF 1.1 4区医学 Q3 MEDICINE, GENERAL & INTERNAL

Internal Medicine Pub Date : 2025-10-01 Epub Date: 2025-03-29 DOI:10.2169/internalmedicine.5094-24

Tasuku Kurokawa, Aoi Takahata, Tadateru Iwayama, Toshiki Sasaki, Takeshi Niizeki, Masafumi Watanabe

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引用次数: 0

摘要

一名77岁男性患者接受了计算机断层扫描（CT）和碘化造影剂的胃癌随访。注射造影剂后，患者出现心脏骤停。术后自发循环心电图显示下导联和V1-3 ST段升高。由于怀疑为I型Kounis综合征（KS），因此静脉注射皮质类固醇和抗组胺药。随后，冠状动脉造影（CAG）显示冠状动脉痉挛，选择性地在冠状动脉内注射硝酸盐成功地解决了每次痉挛。策略性替代造影剂未引起任何额外的过敏反应。本文还讨论了对KS患者进行CAG的最佳时机和首选策略。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Selective Intracoronary Injection of Nitrates Was Effective for Contrast Media-induced Type I Kounis Syndrome After Treatment with Steroids and Antihistamines.

A 77-year-old man presented for computed tomography (CT) with iodinated contrast for follow-up of gastric cancer. After contrast injection, the patient experienced cardiac arrest. A post-return spontaneous circulation electrocardiogram showed ST segment elevation in the inferior leads and V1-3. Since type I Kounis syndrome (KS) was suspected, corticosteroids and antihistamines were administered intravenously. Subsequently, coronary angiography (CAG) revealed coronary spasms, and selective intracoronary injection of nitrates successfully resolved each spasm. Strategic substitution of contrast media did not induce any additional allergic reactions. The optimal timing and preferred strategies for performing CAG in patients with KS were also discussed.

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来源期刊

Internal Medicine 医学-医学：内科

CiteScore

1.90

自引率

8.30%

发文量

审稿时长

2.2 months

期刊介绍： Internal Medicine is an open-access online only journal published monthly by the Japanese Society of Internal Medicine. Articles must be prepared in accordance with "The Uniform Requirements for Manuscripts Submitted to Biomedical Journals (see Annals of Internal Medicine 108: 258-265, 1988), must be contributed solely to the Internal Medicine, and become the property of the Japanese Society of Internal Medicine. Statements contained therein are the responsibility of the author(s). The Society reserves copyright and renewal on all published material and such material may not be reproduced in any form without the written permission of the Society.