妇科恶性手术中乳糜腹水的长期保守治疗1例并文献复习。

IF 0.5 Q4 ONCOLOGY
International Cancer Conference Journal Pub Date : 2025-01-16 eCollection Date: 2025-04-01 DOI:10.1007/s13691-024-00738-7
Mayumi Kamata, Yoichi Aoki, Ai Ikki, Atsushi Murakami, Hiroyuki Kanao
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引用次数: 0

摘要

乳糜腹水是腹部手术中一种罕见的并发症。尽管大多数患者在保守治疗后表现出改善。乳糜腹水长期渗漏可引起营养不良、脱水和免疫抑制;因此,早期治愈是可取的,但乳糜腹水的标准治疗方法尚未建立,确定手术干预的时机是困难的。一名74岁的女性接受了输卵管癌肉瘤的手术,包括骨盆和主动脉旁淋巴结的清扫。术后发现有大量乳糜腹水。此外,低脂饮食,每周进行腹水穿刺和淋巴管造影。然而,泄漏并没有得到解决。术后18周开始禁食、全肠外营养(TPN)、奥曲肽、替替林、纤维γ蛋白强化治疗10周后,乳糜腹水变为浆液性并消失。长期保守治疗可改善乳糜腹水,不进行手术干预的持续保守治疗是一种选择。患者对低脂饮食有抵抗力,尽管禁食和TPN有效。此外,腹水的颜色从乳白色变为浆液色,作为糜烂性腹水改善的前兆,可能有助于考虑手术干预的时机。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Long-term conservative treatment of chylous ascites in gynecological malignant surgery: a case report and literature review.

Chylous ascites is a rare complication of abdominal surgery. Although most patients show improvement with conservative treatment. Long-term leakage of chylous ascites can cause malnutrition, dehydration, and immunosuppression; therefore, an early cure is desirable, but no standard treatment for chylous ascites has been established, and determining the timing of surgical intervention is difficult. A 74-year-old woman underwent surgery for carcinosarcoma of the fallopian tube, including dissection of the pelvic and para-aortic lymph nodes. She was noted to have a large amount of chylous ascites postoperatively. Furthermore, a low-fat diet, weekly ascites punctures and lymphangiography were performed. However, the leakage was not resolved. After ten weeks of intensive treatment with fasting, total parenteral nutrition (TPN), octreotide, etilefrine, and fibrogammin, beginning 18 weeks postoperatively, the chylous ascites changed to serous and disappeared. Long-term conservative treatment may improve chylous ascites, and continued conservative treatment without surgical intervention is an option. The patient was resistant to a low-fat diet, although fasting and TPN were effective. In addition, a change in the color of the ascites from milky white to serous as a precursor to improvement of the erosive ascites may help to consider the timing of surgical intervention.

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来源期刊
自引率
14.30%
发文量
57
期刊介绍: This online-only journal publishes original case reports on all types of cancer. In particular, we welcome not only case reports of educational value in the diagnosis and treatment of cancers, but also reports on molecularly analyzed cancer cases, including gene mutations, gene fusions, gene expression, and changes in copy number, regardless of their known clinical significance. Assessing the molecular analysis of a tumor usually requires a “cancer conference” in which experts from various fields discuss it. Even if the authors and their respective “cancer conference” were unable to determine the clinical significance of molecular changes at the time of submission and publication, their data may provide evidence that will help the scientific community develop precision medicine solutions in the future. We welcome case reports with reviews of the literature on similar cases, as they are more useful and valuable to readers than are reports of rare cases. International Cancer Conference Journal is the official publication of the Japan Society of Clinical Oncology (JSCO). - Presents an online-only collection of original case reports on all types of cancer - In particular, welcomes molecularly analyzed cancer cases - The Official Publication of the Japan Society of Clinical Oncology (JSCO)
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