A Comprehensive Overview of Klebsiella Pneumoniae: Resistance Dynamics, Clinical Manifestations, and Therapeutic Options.

Klebsiella pneumoniae (Kp) is a notable pathogen responsible for various infections. The emergence of hypervirulent and carbapenem-resistant strains has raised global concern. Many novel approaches were developed to combat the current severe situation of antibiotic resistance, and clinical guidelines have also provided corresponding recommendations. This review highlights the critical aspects of Kp, including classification, virulence factors, systemic dissemination, drug resistance progression and the new therapeutic strategies to combat this evolving threat.