NUTRIOSE® soluble fibre supplementation as an effective dietary strategy to improve glycaemic response.

Purpose: Postprandial glycaemic control is critical for diabetes prevention and management. Various dietary strategies have been explored to modulate postprandial glycaemia, with the inclusion of innovative fibres showing promising benefits in reducing daily glycaemic load and improving overall glycaemic control.

Methods: In this study, we conducted an 8-week, randomised, controlled, parallel-arm trial involving 78 healthy adults living in Singapore (average age: 39.9 ± 10.6 years; 48 men and 30 women), who were divided into two subgroups: the overweight group (OG) and the genetic risk group (GRG).

Results: Daily supplementation with 40 g of NUTRIOSE^® soluble fibre significantly improved 24 h glucose homeostasis under free-living conditions. Compared to the postprandial glycaemic response after breakfast and lunch, NUTRIOSE^® supplementation for 8 weeks resulted in a more substantial improvement in the glycaemic response after dinner. Furthermore, one day of NUTRIOSE^® supplementation led to improved glucose management in both participant subgroups, with more significant improvements observed in the OG group compared to the GRG. However, a reduction in appetite following NUTRIOSE^® supplementation was mostly observed in the GRG. Additionally, NUTRIOSE^® consumption led to a decrease in PBFtrunk% and an increase in FFMtrunk in female participants in the GRG.

Conclusion: Incorporating innovative fibres can serve as an effective dietary strategy to lower daily glycaemic load and enhance glycaemic control, offering significant public health benefits and encouraging the consumption of resistant dextrin. However, further investigation into the role of chrono-nutrition is warranted, as it plays a key role in understanding glucose homeostasis throughout the day.