{"title":"玛咖(Lepidium Meyenii Walp.)全球研究现状:热点、爆发和趋势的文献计量学分析。","authors":"Kangjie Li, Chongbo Zhao, Ming Dang, Runxin Ren, Maomao Fu, Yaya Bai, Jing Wang, Qiao Zhang, Fei Luan","doi":"10.2147/DDDT.S499849","DOIUrl":null,"url":null,"abstract":"<p><strong>Purpose: </strong>This bibliometric study aims to comprehensively analyze the research landscape of Maca (<i>Lepidium meyenii</i> Walp.) from 2003 to 2024, identifying key research areas, trends, and patterns, as well as the roles of major countries and institutions in advancing the field.</p><p><strong>Methods: </strong>A quantitative analysis of literature pertaining to Maca was performed utilizing the bibliometric tools VOSviewer, CiteSpace, and R Bibliometrix. This analysis encompassed an examination of publication frequency, author collaboration networks, and keyword co-occurrence patterns.</p><p><strong>Results: </strong>The number of published studies on Maca has increased every year since it was studied, with China, Peru, and the United States being the leading countries studied. Research focuses on pharmacology (hormone regulation, antioxidant effects), nutrition (nutrient composition), phytochemistry (bioactive compounds) and agriculture (cultivation techniques). An important feature of Maca research is international collaboration, including researchers from Asia, Europe, South America, and other regions. Keywords such as \"maca\", \"nutritional composition\" and \"pharmacological action\" are particularly prominent. The study of maca polysaccharides has become a focus area, showing potential in various aspects of health such as immunity and anti-tumor effect.</p><p><strong>Conclusion: </strong>Maca research is growing, with international collaboration crucial. Future research should explore Maca's biological mechanisms deeper, especially those of Maca polysaccharide, and enhance cross-country research comparisons. Our study provides a comprehensive understanding of Maca research trends, guiding further investigations.</p>","PeriodicalId":11290,"journal":{"name":"Drug Design, Development and Therapy","volume":"19 ","pages":"2329-2349"},"PeriodicalIF":4.7000,"publicationDate":"2025-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11956704/pdf/","citationCount":"0","resultStr":"{\"title\":\"Global Research Status of Maca (<i>Lepidium Meyenii</i> Walp.): A Bibliometric Analysis of Hotspots, Bursts, and Trends.\",\"authors\":\"Kangjie Li, Chongbo Zhao, Ming Dang, Runxin Ren, Maomao Fu, Yaya Bai, Jing Wang, Qiao Zhang, Fei Luan\",\"doi\":\"10.2147/DDDT.S499849\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Purpose: </strong>This bibliometric study aims to comprehensively analyze the research landscape of Maca (<i>Lepidium meyenii</i> Walp.) from 2003 to 2024, identifying key research areas, trends, and patterns, as well as the roles of major countries and institutions in advancing the field.</p><p><strong>Methods: </strong>A quantitative analysis of literature pertaining to Maca was performed utilizing the bibliometric tools VOSviewer, CiteSpace, and R Bibliometrix. This analysis encompassed an examination of publication frequency, author collaboration networks, and keyword co-occurrence patterns.</p><p><strong>Results: </strong>The number of published studies on Maca has increased every year since it was studied, with China, Peru, and the United States being the leading countries studied. Research focuses on pharmacology (hormone regulation, antioxidant effects), nutrition (nutrient composition), phytochemistry (bioactive compounds) and agriculture (cultivation techniques). An important feature of Maca research is international collaboration, including researchers from Asia, Europe, South America, and other regions. Keywords such as \\\"maca\\\", \\\"nutritional composition\\\" and \\\"pharmacological action\\\" are particularly prominent. The study of maca polysaccharides has become a focus area, showing potential in various aspects of health such as immunity and anti-tumor effect.</p><p><strong>Conclusion: </strong>Maca research is growing, with international collaboration crucial. Future research should explore Maca's biological mechanisms deeper, especially those of Maca polysaccharide, and enhance cross-country research comparisons. Our study provides a comprehensive understanding of Maca research trends, guiding further investigations.</p>\",\"PeriodicalId\":11290,\"journal\":{\"name\":\"Drug Design, Development and Therapy\",\"volume\":\"19 \",\"pages\":\"2329-2349\"},\"PeriodicalIF\":4.7000,\"publicationDate\":\"2025-03-27\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11956704/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Drug Design, Development and Therapy\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.2147/DDDT.S499849\",\"RegionNum\":2,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2025/1/1 0:00:00\",\"PubModel\":\"eCollection\",\"JCR\":\"Q1\",\"JCRName\":\"CHEMISTRY, MEDICINAL\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Drug Design, Development and Therapy","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.2147/DDDT.S499849","RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/1/1 0:00:00","PubModel":"eCollection","JCR":"Q1","JCRName":"CHEMISTRY, MEDICINAL","Score":null,"Total":0}
Global Research Status of Maca (Lepidium Meyenii Walp.): A Bibliometric Analysis of Hotspots, Bursts, and Trends.
Purpose: This bibliometric study aims to comprehensively analyze the research landscape of Maca (Lepidium meyenii Walp.) from 2003 to 2024, identifying key research areas, trends, and patterns, as well as the roles of major countries and institutions in advancing the field.
Methods: A quantitative analysis of literature pertaining to Maca was performed utilizing the bibliometric tools VOSviewer, CiteSpace, and R Bibliometrix. This analysis encompassed an examination of publication frequency, author collaboration networks, and keyword co-occurrence patterns.
Results: The number of published studies on Maca has increased every year since it was studied, with China, Peru, and the United States being the leading countries studied. Research focuses on pharmacology (hormone regulation, antioxidant effects), nutrition (nutrient composition), phytochemistry (bioactive compounds) and agriculture (cultivation techniques). An important feature of Maca research is international collaboration, including researchers from Asia, Europe, South America, and other regions. Keywords such as "maca", "nutritional composition" and "pharmacological action" are particularly prominent. The study of maca polysaccharides has become a focus area, showing potential in various aspects of health such as immunity and anti-tumor effect.
Conclusion: Maca research is growing, with international collaboration crucial. Future research should explore Maca's biological mechanisms deeper, especially those of Maca polysaccharide, and enhance cross-country research comparisons. Our study provides a comprehensive understanding of Maca research trends, guiding further investigations.
期刊介绍:
Drug Design, Development and Therapy is an international, peer-reviewed, open access journal that spans the spectrum of drug design, discovery and development through to clinical applications.
The journal is characterized by the rapid reporting of high-quality original research, reviews, expert opinions, commentary and clinical studies in all therapeutic areas.
Specific topics covered by the journal include:
Drug target identification and validation
Phenotypic screening and target deconvolution
Biochemical analyses of drug targets and their pathways
New methods or relevant applications in molecular/drug design and computer-aided drug discovery*
Design, synthesis, and biological evaluation of novel biologically active compounds (including diagnostics or chemical probes)
Structural or molecular biological studies elucidating molecular recognition processes
Fragment-based drug discovery
Pharmaceutical/red biotechnology
Isolation, structural characterization, (bio)synthesis, bioengineering and pharmacological evaluation of natural products**
Distribution, pharmacokinetics and metabolic transformations of drugs or biologically active compounds in drug development
Drug delivery and formulation (design and characterization of dosage forms, release mechanisms and in vivo testing)
Preclinical development studies
Translational animal models
Mechanisms of action and signalling pathways
Toxicology
Gene therapy, cell therapy and immunotherapy
Personalized medicine and pharmacogenomics
Clinical drug evaluation
Patient safety and sustained use of medicines.