利用人工智能进行三阴性乳腺癌的精确诊断和治疗。

IF 2.9 3区 医学 Q2 ONCOLOGY
Md Sadique Hussain, Prasanna Srinivasan Ramalingam, Gayathri Chellasamy, Kyusik Yun, Ajay Singh Bisht, Gaurav Gupta
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引用次数: 0

摘要

三阴性乳腺癌(TNBC)是一种高度侵袭性的乳腺癌(BC)亚型,其特征是缺乏雌激素、孕激素和HER2受体,导致治疗选择有限。本文批判性地探讨了人工智能(AI)在提高TNBC治疗的诊断和治疗中的作用。我们首先讨论TNBC的发病率和精准医学的基础,强调需要创新的诊断和治疗方法。目前的诊断方法,包括传统的成像技术和组织病理学评估,表现出局限性,如延迟诊断和解释差异。本文重点介绍了人工智能在图像分析,生物标志物发现和多组学数据集成方面的进步,从而提高了诊断和治疗的精度和效率。在治疗方面,人工智能促进了个性化的治疗策略,加速了药物的发现,并实现了对患者反应的实时监测。然而,挑战依然存在,包括与数据质量、模型可解释性和人工智能实施的社会影响相关的问题。在结论中,我们讨论了将人工智能融入临床实践的未来前景,并强调了多学科合作的重要性。本综述旨在概述关键趋势,并为利用人工智能改善TNBC管理结果提供建议,同时强调进一步研究的必要性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Harnessing Artificial Intelligence for Precision Diagnosis and Treatment of Triple Negative Breast Cancer.

Triple-Negative Breast Cancer (TNBC) is a highly aggressive subtype of breast cancer (BC) characterized by the absence of estrogen, progesterone, and HER2 receptors, resulting in limited therapeutic options. This article critically examines the role of Artificial Intelligence (AI) in enhancing the diagnosis and treatment of TNBC treatment. We begin by discussing the incidence of TNBC and the fundamentals of precision medicine, emphasizing the need for innovative diagnostic and therapeutic approaches. Current diagnostic methods, including conventional imaging techniques and histopathological assessments, exhibit limitations such as delayed diagnosis and interpretative discrepancies. This article highlights AI-driven advancements in image analysis, biomarker discovery, and the integration of multi-omics data, leading to enhanced precision and efficiency in diagnosis and treatment. In treatment, AI facilitates personalized therapeutic strategies, accelerates drug discovery, and enables real-time monitoring of patient responses. However, challenges persist, including issues related to data quality, model interpretability, and the societal impact of AI implementation. In the conclusion, we discuss the future prospects of integrating AI into clinical practice and emphasize the importance of multidisciplinary collaboration. This review aims to outline key trends and provide recommendations for utilizing AI to improve TNBC management outcomes, while highlighting the need for further research.

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来源期刊
Clinical breast cancer
Clinical breast cancer 医学-肿瘤学
CiteScore
5.40
自引率
3.20%
发文量
174
审稿时长
48 days
期刊介绍: Clinical Breast Cancer is a peer-reviewed bimonthly journal that publishes original articles describing various aspects of clinical and translational research of breast cancer. Clinical Breast Cancer is devoted to articles on detection, diagnosis, prevention, and treatment of breast cancer. The main emphasis is on recent scientific developments in all areas related to breast cancer. Specific areas of interest include clinical research reports from various therapeutic modalities, cancer genetics, drug sensitivity and resistance, novel imaging, tumor genomics, biomarkers, and chemoprevention strategies.
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