生物相容性硅钼酸促进一锅快速合成1,2,3- nh -三唑。

IF 2.9 3区化学 Q1 CHEMISTRY, ORGANIC

Organic & Biomolecular Chemistry Pub Date : 2025-03-24 DOI:10.1039/d5ob00298b

Danish Ansari , Manoj K. Jaiswal , Mangal S. Yadav , Vinay K. Pandey , Mayank Singh , Vinod K. Tiwari

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引用次数: 0

摘要

本工作描述了一种新的实用方法，通过多组分反应，包括醛、硝基烷和叠氮化钠，在5 mol%的硅钼酸（SMA）存在下，一锅制备4-芳基- nh -1,2,3-三唑和4-糖基- nh -1,2,3-三唑。SMA是一种多功能和生物相容性催化剂。一锅连续形成C-C和C-N键，反应产率高，催化剂的生物相容性，易于处理，以及1,2,3-三唑的底物范围广是本方案的显著优点。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

Biocompatible silicomolybdic acid-promoted one-pot expeditious synthesis of 1,2,3-NH-triazoles†

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Biocompatible silicomolybdic acid-promoted one-pot expeditious synthesis of 1,2,3-NH-triazoles†

The present work describes a new and practical approach for the one-pot preparation of 4-aryl-NH-1,2,3-triazoles and 4-glycosyl-NH-1,2,3-triazoles from a multicomponent reaction involving aldehydes, nitroalkanes, and sodium azide in the presence of 5 mol% of silicomolybdic acid (SMA) as a versatile and biocompatible catalyst. One-pot sequential formation of C–C and C–N bonds, high reaction yield, biocompatible nature of catalyst, easy handling, and broad substrate scope of 1,2,3-triazoles are the notable advantages of the present protocol.

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来源期刊

Organic & Biomolecular Chemistry 化学-有机化学

CiteScore

5.50

自引率

9.40%

发文量

1056

审稿时长

1.3 months

期刊介绍： Organic & Biomolecular Chemistry is an international journal using integrated research in chemistry-organic chemistry. Founded in 2003 by the Royal Society of Chemistry, the journal is published in Semimonthly issues and has been indexed by SCIE, a leading international database. The journal focuses on the key research and cutting-edge progress in the field of chemistry-organic chemistry, publishes and reports the research results in this field in a timely manner, and is committed to becoming a window and platform for rapid academic exchanges among peers in this field. The journal's impact factor in 2023 is 2.9, and its CiteScore is 5.5.