Danish Ansari , Manoj K. Jaiswal , Mangal S. Yadav , Vinay K. Pandey , Mayank Singh , Vinod K. Tiwari
{"title":"生物相容性硅钼酸促进一锅快速合成1,2,3- nh -三唑。","authors":"Danish Ansari , Manoj K. Jaiswal , Mangal S. Yadav , Vinay K. Pandey , Mayank Singh , Vinod K. Tiwari","doi":"10.1039/d5ob00298b","DOIUrl":null,"url":null,"abstract":"<div><div>The present work describes a new and practical approach for the one-pot preparation of 4-aryl-<em>NH</em>-1,2,3-triazoles and 4-glycosyl-<em>NH</em>-1,2,3-triazoles from a multicomponent reaction involving aldehydes, nitroalkanes, and sodium azide in the presence of 5 mol% of silicomolybdic acid (SMA) as a versatile and biocompatible catalyst. One-pot sequential formation of C–C and C–N bonds, high reaction yield, biocompatible nature of catalyst, easy handling, and broad substrate scope of 1,2,3-triazoles are the notable advantages of the present protocol.</div></div>","PeriodicalId":96,"journal":{"name":"Organic & Biomolecular Chemistry","volume":"23 17","pages":"Pages 4045-4057"},"PeriodicalIF":2.9000,"publicationDate":"2025-03-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Biocompatible silicomolybdic acid-promoted one-pot expeditious synthesis of 1,2,3-NH-triazoles†\",\"authors\":\"Danish Ansari , Manoj K. Jaiswal , Mangal S. Yadav , Vinay K. Pandey , Mayank Singh , Vinod K. Tiwari\",\"doi\":\"10.1039/d5ob00298b\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><div>The present work describes a new and practical approach for the one-pot preparation of 4-aryl-<em>NH</em>-1,2,3-triazoles and 4-glycosyl-<em>NH</em>-1,2,3-triazoles from a multicomponent reaction involving aldehydes, nitroalkanes, and sodium azide in the presence of 5 mol% of silicomolybdic acid (SMA) as a versatile and biocompatible catalyst. One-pot sequential formation of C–C and C–N bonds, high reaction yield, biocompatible nature of catalyst, easy handling, and broad substrate scope of 1,2,3-triazoles are the notable advantages of the present protocol.</div></div>\",\"PeriodicalId\":96,\"journal\":{\"name\":\"Organic & Biomolecular Chemistry\",\"volume\":\"23 17\",\"pages\":\"Pages 4045-4057\"},\"PeriodicalIF\":2.9000,\"publicationDate\":\"2025-03-24\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Organic & Biomolecular Chemistry\",\"FirstCategoryId\":\"92\",\"ListUrlMain\":\"https://www.sciencedirect.com/org/science/article/pii/S1477052025002368\",\"RegionNum\":3,\"RegionCategory\":\"化学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"CHEMISTRY, ORGANIC\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Organic & Biomolecular Chemistry","FirstCategoryId":"92","ListUrlMain":"https://www.sciencedirect.com/org/science/article/pii/S1477052025002368","RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"CHEMISTRY, ORGANIC","Score":null,"Total":0}
Biocompatible silicomolybdic acid-promoted one-pot expeditious synthesis of 1,2,3-NH-triazoles†
The present work describes a new and practical approach for the one-pot preparation of 4-aryl-NH-1,2,3-triazoles and 4-glycosyl-NH-1,2,3-triazoles from a multicomponent reaction involving aldehydes, nitroalkanes, and sodium azide in the presence of 5 mol% of silicomolybdic acid (SMA) as a versatile and biocompatible catalyst. One-pot sequential formation of C–C and C–N bonds, high reaction yield, biocompatible nature of catalyst, easy handling, and broad substrate scope of 1,2,3-triazoles are the notable advantages of the present protocol.
期刊介绍:
Organic & Biomolecular Chemistry is an international journal using integrated research in chemistry-organic chemistry. Founded in 2003 by the Royal Society of Chemistry, the journal is published in Semimonthly issues and has been indexed by SCIE, a leading international database. The journal focuses on the key research and cutting-edge progress in the field of chemistry-organic chemistry, publishes and reports the research results in this field in a timely manner, and is committed to becoming a window and platform for rapid academic exchanges among peers in this field. The journal's impact factor in 2023 is 2.9, and its CiteScore is 5.5.