埃塞俄比亚和尼日利亚2型糖尿病患病率和临床资料的比较分析

IF 3 2区 医学 Q2 ENDOCRINOLOGY & METABOLISM
Assefa Mulu Baye, Teferi Gedif Fenta, Suvi Karuranga, Ifeyinwa Dorothy Nnakenyi, Ekenechukwu Esther Young, Colin Palmer, Ewan R. Pearson, Ifeoma Isabella Ulasi, Adem Y. Dawed
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引用次数: 0

摘要

目的:我们旨在确定埃塞俄比亚和尼日利亚2型糖尿病的患病率和临床概况。方法采用多阶段抽样方法,于2020年11月1日至2021年10月21日对1727人进行社区横断面研究。采用了世卫组织的STEPs工具。采用空腹和口服葡萄糖耐量试验进行筛查,并采用美国糖尿病协会(ADA)的诊断标准。使用Stata version 17进行分析。采用方差分析(ANOVA)和卡方检验进行变量比较。p值小于0.05时宣布显著性。结果男性872人(50.5%),平均年龄44.6岁。糖尿病前期和糖尿病的总体患病率分别为15.8%和7.0%。空腹血糖和葡萄糖耐量受损分别为11.8%和11.5%。新诊断糖尿病的患病率空腹为3.4%,口服糖耐量试验为4.0%。与糖尿病前期和糖尿病患者相比,血糖正常的参与者更年轻,体重、体重指数(BMI)、腰围、舒张压和收缩压以及高血压病史都更低。结论:在本研究中,研究环境中糖尿病和前驱糖尿病的患病率明显较高。与尼日利亚和西方国家相比,埃塞俄比亚的糖尿病患者具有不同的人体测量学和临床特征,其特点是发病年龄小、身体消瘦、BMI较低、腰围较小。因此,糖尿病的管理应量身定制的独特的生理和临床概况的人口。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Comparative Analysis of Type 2 Diabetes Prevalence and Clinical Profiles in Ethiopia and Nigeria

Comparative Analysis of Type 2 Diabetes Prevalence and Clinical Profiles in Ethiopia and Nigeria

Aims

We aimed to determine the prevalence of diabetes and the clinical profiles of Type 2 diabetes in Ethiopia and Nigeria.

Methods

A community-based cross-sectional study was carried out from November 01, 2020 to October 21, 2021 among 1727 participants using a multistage sampling method. The WHO's STEPs tool was employed. Both fasting and oral glucose tolerance tests were used for screening and American Diabetes Association's (ADA's) diagnostic criteria was used. Stata version 17 was used for analysis. Analysis of Variance (ANOVA) and the Chi-square test were used to compare variables. Significance was declared at a p-value less than 0.05.

Result

Of the surveyed participants, 872 (50.5%) were men and the mean age was 44.6 years. The overall prevalence of prediabetes and diabetes was 15.8% and 7.0%, respectively. Impaired fasting glycaemia and glucose tolerance were 11.8% and 11.5%, respectively. The prevalence of newly diagnosed diabetes was 3.4% by fasting and 4.0% by oral glucose tolerance test. Participants with normal blood glucose were younger and had a lower weight, body mass index (BMI), waist circumference, diastolic, and systolic blood pressure, and history of hypertension than those with prediabetes and diabetes.

Conclusion

In the present study, there is a notably high diabetes and prediabetes prevalence in the study settings. Individuals with diabetes in Ethiopia compared to Nigeria and the West have different anthropometric and clinical profiles characterized by a young age of onset, leanness, lower BMI, and waist circumference. Hence, the management of diabetes shall be tailored to the unique physiologic and clinical profiles of the population.

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来源期刊
Journal of Diabetes
Journal of Diabetes ENDOCRINOLOGY & METABOLISM-
CiteScore
6.50
自引率
2.20%
发文量
94
审稿时长
>12 weeks
期刊介绍: Journal of Diabetes (JDB) devotes itself to diabetes research, therapeutics, and education. It aims to involve researchers and practitioners in a dialogue between East and West via all aspects of epidemiology, etiology, pathogenesis, management, complications and prevention of diabetes, including the molecular, biochemical, and physiological aspects of diabetes. The Editorial team is international with a unique mix of Asian and Western participation. The Editors welcome submissions in form of original research articles, images, novel case reports and correspondence, and will solicit reviews, point-counterpoint, commentaries, editorials, news highlights, and educational content.
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