之字形支架径向刚度的解析建模与验证：实验与数值方法

IF 3.2 4区医学 Q2 ENGINEERING, BIOMEDICAL

Journal of biomedical materials research. Part B, Applied biomaterials Pub Date : 2025-04-02 DOI:10.1002/jbm.b.35574

Moshe Brand, Nadav Sharon

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引用次数: 0

摘要

支架和支架移植物（SGs）用于许多血管内手术。临床研究表明，支架的径向刚度（RS）增加了对动脉壁的压力，这可能导致再狭窄，在某些情况下，需要反复干预。本研究旨在验证一种用于计算锯齿形支架和SG的RS的分析模型。选择了四种不同几何尺寸和材料性能的商用SGs。分析模型的RS计算结果与实验测量和数值模型预测结果进行了比较。实验系统测得的RS值与分析模型计算的RS值吻合良好，平均差值为2.4%±3.3%。分析模型的验证使支架设计具有理想的RS，最适合特定患者。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

Analytical Modeling and Validation of Radial Stiffness in Zigzag-Shaped Stents: Experimental and Numerical Approaches

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Analytical Modeling and Validation of Radial Stiffness in Zigzag-Shaped Stents: Experimental and Numerical Approaches

Stents and stent grafts (SGs) are used in many endovascular procedures. Clinical studies have revealed that radial stiffness (RS) in stents increases pressure on the artery wall, which can cause restenosis and, in some cases, require repeated intervention. This study aimed to validate an analytical model for calculating the RS of stents and SG with a zigzag-shaped structure. Four commercial SGs with varying geometric dimensions and material properties were selected. The analytical model's RS calculations were compared with experimental measurements and numerical model predictions. An excellent agreement was observed between the RS values measured in the experimental system and those calculated in the analytical model, with an average difference of 2.4% ± 3.3%. Validation of the analytical model enables the design of stents with a desired RS that is optimally suited to a specific patient.

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来源期刊

Journal of biomedical materials research. Part B, Applied biomaterials 工程技术-材料科学：生物材料

CiteScore

7.50

自引率

2.90%

发文量

199

审稿时长

12 months

期刊介绍： Journal of Biomedical Materials Research – Part B: Applied Biomaterials is a highly interdisciplinary peer-reviewed journal serving the needs of biomaterials professionals who design, develop, produce and apply biomaterials and medical devices. It has the common focus of biomaterials applied to the human body and covers all disciplines where medical devices are used. Papers are published on biomaterials related to medical device development and manufacture, degradation in the body, nano- and biomimetic- biomaterials interactions, mechanics of biomaterials, implant retrieval and analysis, tissue-biomaterial surface interactions, wound healing, infection, drug delivery, standards and regulation of devices, animal and pre-clinical studies of biomaterials and medical devices, and tissue-biopolymer-material combination products. Manuscripts are published in one of six formats: • original research reports • short research and development reports • scientific reviews • current concepts articles • special reports • editorials Journal of Biomedical Materials Research – Part B: Applied Biomaterials is an official journal of the Society for Biomaterials, Japanese Society for Biomaterials, the Australasian Society for Biomaterials, and the Korean Society for Biomaterials. Manuscripts from all countries are invited but must be in English. Authors are not required to be members of the affiliated Societies, but members of these societies are encouraged to submit their work to the journal for consideration.