Jay Krishnan, Manuela Carugati, Rachel A. Miller, Cameron R. Wolfe, John R. Perfect, Julia A. Messina
{"title":"揭露真相的心脏:原位心脏移植受者中供体来源的侵袭性真菌感染","authors":"Jay Krishnan, Manuela Carugati, Rachel A. Miller, Cameron R. Wolfe, John R. Perfect, Julia A. Messina","doi":"10.1016/j.mmcr.2025.100702","DOIUrl":null,"url":null,"abstract":"<div><div>Donor-derived invasive fungal infections among solid organ transplant recipients are rare but sometimes devastating events associated with notable morbidity and mortality. Here we describe two donor-derived fungal infections – one <em>Candida parapsilosis</em> complex infection and one <em>Aspergillus fumigatus</em> infection – that occurred among heart transplant recipients at a quaternary care center. Both recipients survived their infections, though with substantial morbidity despite aggressive surgical intervention and antifungal therapy.</div></div>","PeriodicalId":51724,"journal":{"name":"Medical Mycology Case Reports","volume":"48 ","pages":"Article 100702"},"PeriodicalIF":1.6000,"publicationDate":"2025-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"The tell-tale hearts: Donor-derived invasive fungal infections among orthotopic heart transplant recipients\",\"authors\":\"Jay Krishnan, Manuela Carugati, Rachel A. Miller, Cameron R. Wolfe, John R. Perfect, Julia A. Messina\",\"doi\":\"10.1016/j.mmcr.2025.100702\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><div>Donor-derived invasive fungal infections among solid organ transplant recipients are rare but sometimes devastating events associated with notable morbidity and mortality. Here we describe two donor-derived fungal infections – one <em>Candida parapsilosis</em> complex infection and one <em>Aspergillus fumigatus</em> infection – that occurred among heart transplant recipients at a quaternary care center. Both recipients survived their infections, though with substantial morbidity despite aggressive surgical intervention and antifungal therapy.</div></div>\",\"PeriodicalId\":51724,\"journal\":{\"name\":\"Medical Mycology Case Reports\",\"volume\":\"48 \",\"pages\":\"Article 100702\"},\"PeriodicalIF\":1.6000,\"publicationDate\":\"2025-03-31\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Medical Mycology Case Reports\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S2211753925000119\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"MEDICINE, RESEARCH & EXPERIMENTAL\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Medical Mycology Case Reports","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2211753925000119","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"MEDICINE, RESEARCH & EXPERIMENTAL","Score":null,"Total":0}
The tell-tale hearts: Donor-derived invasive fungal infections among orthotopic heart transplant recipients
Donor-derived invasive fungal infections among solid organ transplant recipients are rare but sometimes devastating events associated with notable morbidity and mortality. Here we describe two donor-derived fungal infections – one Candida parapsilosis complex infection and one Aspergillus fumigatus infection – that occurred among heart transplant recipients at a quaternary care center. Both recipients survived their infections, though with substantial morbidity despite aggressive surgical intervention and antifungal therapy.