揭示卡塔尔心血管疾病的未来生产力负担：调查2型糖尿病可改变的危险因素控制

IF 4.3 Q1 CARDIAC & CARDIOVASCULAR SYSTEMS

American journal of preventive cardiology Pub Date : 2025-03-11 DOI:10.1016/j.ajpc.2025.100961

Dina Abushanab , Daoud Al-Badriyeh , Danny Liew , Zanfina Ademi

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引用次数: 0

摘要

目的不充分的风险因素控制可能导致数百万生产力调整生命年（PALYs）的损失。我们旨在评估2型糖尿病（T2D）患者心血管疾病（CVD）的生产力负担，并研究在卡塔尔加强控制可改变的CVD危险因素的潜在优势。材料和方法建立模型，量化2024年至2033年40-65岁卡塔尔T2D患者CVD的生产力负担（按PALYs计算）。PALYs的财务价值是根据每名全职工人的国内生产总值（即80 573美元）确定的。基本情况模型估计了CVD的生产力负担，并模拟了干预方案，以评估改善控制可改变的危险因素所带来的潜在收益，包括降低T2D发病率、降低收缩压（SBP）、减少吸烟者数量和降低总胆固醇。所有的成本和结果都以3%的年折现率计算。结果基本病例分析预测，T2D患者的心血管疾病将导致约2,096,536例paly(95%置信区间，1,689,272-2,182,939)，为该国GDP贡献225.46亿美元（95%置信区间，1,689,272-2,182,939）。然而，实施降低T2D发病率、降低收缩压、减少吸烟者数量和改善总胆固醇的干预措施可分别获得200,408、198,173、194,725和113,462个PALYs。这些改善还将分别带来200.1亿美元、201.7亿美元、1978亿美元和127.9亿美元的经济收益。结论实施优先控制和预防心血管疾病风险因素的干预措施有助于提高我国的整体生产力。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

Unraveling the future productivity burden of cardiovascular disease in Qatar: Investigating the modifiable risk factors control in type 2 diabetes

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Unraveling the future productivity burden of cardiovascular disease in Qatar: Investigating the modifiable risk factors control in type 2 diabetes

Aims

Insufficient risk factor control can lead to a loss of millions of productivity-adjusted life years (PALYs). We aimed to assess the productivity burden of cardiovascular disease (CVD) in type 2 diabetes (T2D) and examine the potential advantages of enhancing the control of modifiable CVD risk factors in Qatar.

Materials and methods

Models were developed to quantify the productivity burden, in terms of PALYs, of CVD in Qataris with T2D, aged 40–65 years, from 2024 to 2033. The financial value of PALYs was determined based on the gross domestic product (GDP) per full-time worker (i.e. US$80,573). The base-case model estimated the productivity burden of CVD, and interventional scenarios were simulated to assess potential gains resulting from improved control of modifiable risk factors, including reduced incidence of T2D, lower systolic blood pressure (SBP), decreased number of smokers, and reduced total cholesterol. All costs and outcomes were discounted at an annual rate of 3 %.

Results

The base-case analysis projected that CVD in T2D would result in an estimated 2,096,536 PALYs (95 % confidence interval, 1,689,272–2,182,939), contributing US$225.46 (95 %CI, 1,689,272–2,182,939) billion to the country's GDP. However, implementing interventions to decrease the T2D incidence, lower SBP, reduce the number of smokers, and improve the total cholesterol could yield gains of 200,408, 198,173, 194,725, and 113,462 PALYs, respectively. These improvements would also lead to economic gains of US$20.01 billion, US$20.17 billion, US$19.78, and US$12.79 billion, respectively.