Qinyi Bao MD , Zhuo Wang MD , Jian’an Wang MD, PhD , Yixin Ruan MD, PhD
{"title":"2021年亚洲GBD高温引起的缺血性心脏病负担的流行病学研究","authors":"Qinyi Bao MD , Zhuo Wang MD , Jian’an Wang MD, PhD , Yixin Ruan MD, PhD","doi":"10.1016/j.jacasi.2024.12.012","DOIUrl":null,"url":null,"abstract":"<div><h3>Background</h3><div>Ischemic heart disease (IHD) posed the highest global disease burden in 2021, with regional disparities in Asia. Moreover, climate change is exacerbating population exposure to high temperatures (Hi-Tem).</div></div><div><h3>Objectives</h3><div>This study aimed to systematically assess the burden of IHD attributed to Hi-Tem in Asia, considering geographic and demographic factors.</div></div><div><h3>Methods</h3><div>The Global Burden of Disease Study 2021 tools evaluated the IHD burden from Hi-Tem in Asia, and decomposition analysis was conducted to further explore the potential burden drivers.</div></div><div><h3>Results</h3><div>Asia witnessed a significant increase in IHD burden caused by Hi-Tem, with 88,450 (95% UI: 15,815-188,816) deaths and 2,112,025.42 (95% UI: 456,758.65-4,325,643.47) disability-adjusted life years in 2021. Over the past 3 decades, the burden increased annually by 1.63% (95% CI: 1.25%-2.01%) in age-standardized mortality rate and by 1.60% (95% CI: 1.21%-1.99%) in age-standardized rate of disability-adjusted life years. Notably, South Asia bore the heaviest burden, whereas high-income Asia Pacific had the lightest. Men and older persons consistently faced a higher IHD burden from Hi-Tem. Despite generally balanced contributions from population growth, aging, and epidemiological changes, regional disparities may persist.</div></div><div><h3>Conclusions</h3><div>Our study provides a comprehensive overview of the demographic and geographic characteristics of the IHD burden attributable to Hi-Tem in Asia from 1990 to 2021. In summary, Asia's IHD burden caused by Hi-Tem rose significantly, with the greater impact on men and older populations.</div></div>","PeriodicalId":73529,"journal":{"name":"JACC. Asia","volume":"5 4","pages":"Pages 528-540"},"PeriodicalIF":0.0000,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Epidemiology of Ischemic Heart Disease Burden Attributable to High Temperature in Asia From GBD 2021\",\"authors\":\"Qinyi Bao MD , Zhuo Wang MD , Jian’an Wang MD, PhD , Yixin Ruan MD, PhD\",\"doi\":\"10.1016/j.jacasi.2024.12.012\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><h3>Background</h3><div>Ischemic heart disease (IHD) posed the highest global disease burden in 2021, with regional disparities in Asia. Moreover, climate change is exacerbating population exposure to high temperatures (Hi-Tem).</div></div><div><h3>Objectives</h3><div>This study aimed to systematically assess the burden of IHD attributed to Hi-Tem in Asia, considering geographic and demographic factors.</div></div><div><h3>Methods</h3><div>The Global Burden of Disease Study 2021 tools evaluated the IHD burden from Hi-Tem in Asia, and decomposition analysis was conducted to further explore the potential burden drivers.</div></div><div><h3>Results</h3><div>Asia witnessed a significant increase in IHD burden caused by Hi-Tem, with 88,450 (95% UI: 15,815-188,816) deaths and 2,112,025.42 (95% UI: 456,758.65-4,325,643.47) disability-adjusted life years in 2021. Over the past 3 decades, the burden increased annually by 1.63% (95% CI: 1.25%-2.01%) in age-standardized mortality rate and by 1.60% (95% CI: 1.21%-1.99%) in age-standardized rate of disability-adjusted life years. Notably, South Asia bore the heaviest burden, whereas high-income Asia Pacific had the lightest. Men and older persons consistently faced a higher IHD burden from Hi-Tem. Despite generally balanced contributions from population growth, aging, and epidemiological changes, regional disparities may persist.</div></div><div><h3>Conclusions</h3><div>Our study provides a comprehensive overview of the demographic and geographic characteristics of the IHD burden attributable to Hi-Tem in Asia from 1990 to 2021. In summary, Asia's IHD burden caused by Hi-Tem rose significantly, with the greater impact on men and older populations.</div></div>\",\"PeriodicalId\":73529,\"journal\":{\"name\":\"JACC. 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Epidemiology of Ischemic Heart Disease Burden Attributable to High Temperature in Asia From GBD 2021
Background
Ischemic heart disease (IHD) posed the highest global disease burden in 2021, with regional disparities in Asia. Moreover, climate change is exacerbating population exposure to high temperatures (Hi-Tem).
Objectives
This study aimed to systematically assess the burden of IHD attributed to Hi-Tem in Asia, considering geographic and demographic factors.
Methods
The Global Burden of Disease Study 2021 tools evaluated the IHD burden from Hi-Tem in Asia, and decomposition analysis was conducted to further explore the potential burden drivers.
Results
Asia witnessed a significant increase in IHD burden caused by Hi-Tem, with 88,450 (95% UI: 15,815-188,816) deaths and 2,112,025.42 (95% UI: 456,758.65-4,325,643.47) disability-adjusted life years in 2021. Over the past 3 decades, the burden increased annually by 1.63% (95% CI: 1.25%-2.01%) in age-standardized mortality rate and by 1.60% (95% CI: 1.21%-1.99%) in age-standardized rate of disability-adjusted life years. Notably, South Asia bore the heaviest burden, whereas high-income Asia Pacific had the lightest. Men and older persons consistently faced a higher IHD burden from Hi-Tem. Despite generally balanced contributions from population growth, aging, and epidemiological changes, regional disparities may persist.
Conclusions
Our study provides a comprehensive overview of the demographic and geographic characteristics of the IHD burden attributable to Hi-Tem in Asia from 1990 to 2021. In summary, Asia's IHD burden caused by Hi-Tem rose significantly, with the greater impact on men and older populations.
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