拥抱未知：人类微生物组的蛋白质组学见解

IF 27.7 1区生物学 Q1 CELL BIOLOGY

Cell metabolism Pub Date : 2025-04-01 DOI:10.1016/j.cmet.2025.02.003

Shuqin Zeng, Alexandre Almeida, Dezhi Mu, Shaopu Wang

引用次数: 0

摘要

对人类微生物组的蛋白质水平调查提供了对活性微生物功能的见解。最近，vald -马斯等人1介绍了一种宏基因组信息宏蛋白质组学方法，用于功能性探索物种水平微生物组与宿主的相互作用，并量化饮食暴露量。它的潜力已经在小鼠和人类身上实现，以揭示健康和炎症性肠病的蛋白质组学特征。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Embracing the unknown: Proteomic insights into the human microbiome

Protein-level investigations into the human microbiome provide insights into active microbial functions. Recently, Valdés-Mas et al.¹ introduced a metagenome-informed metaproteomics approach to functionally explore species-level microbiome-host interactions and quantify the dietary exposome. Its potential has been implemented in mice and humans to uncover proteomic signatures of health and inflammatory bowel disease.

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来源期刊

Cell metabolism 生物-内分泌学与代谢

CiteScore

48.60

自引率

1.40%

发文量

173

审稿时长

2.5 months

期刊介绍： Cell Metabolism is a top research journal established in 2005 that focuses on publishing original and impactful papers in the field of metabolic research.It covers a wide range of topics including diabetes, obesity, cardiovascular biology, aging and stress responses, circadian biology, and many others. Cell Metabolism aims to contribute to the advancement of metabolic research by providing a platform for the publication and dissemination of high-quality research and thought-provoking articles.