CombiCells允许组合显示细胞表面配体

IF 67.7 1区医学 Q1 IMMUNOLOGY

Nature Reviews Immunology Pub Date : 2025-04-01 DOI:10.1038/s41577-025-01168-z

Sofia Bustamante Eguiguren

引用次数: 0

摘要

在这篇贸易工具的文章中，Sofia Bustamante Eguiguren（来自Dushek和van der Merwe实验室）描述了CombiCells，它可以定制表达任何配体的组合和浓度，以研究受体-配体的相互作用。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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CombiCells allow combinatorial display of cell surface ligands

In this Tools of the Trade article, Sofia Bustamante Eguiguren (from the Dushek and van der Merwe labs) describes CombiCells, which can be customized to express any combination and concentration of ligands to study receptor–ligands interactions.

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来源期刊

Nature Reviews Immunology 医学-免疫学

CiteScore

93.40

自引率

0.40%

发文量

131

审稿时长

6-12 weeks

期刊介绍： Nature Reviews Immunology is a journal that provides comprehensive coverage of all areas of immunology, including fundamental mechanisms and applied aspects. It has two international standard serial numbers (ISSN): 1474-1733 for print and 1474-1741 for online. In addition to review articles, the journal also features recent developments and new primary papers in the field, as well as reflections on influential people, papers, and events in the development of immunology. The subjects covered by Nature Reviews Immunology include allergy and asthma, autoimmunity, antigen processing and presentation, apoptosis and cell death, chemokines and chemokine receptors, cytokines and cytokine receptors, development and function of cells of the immune system, haematopoiesis, infection and immunity, immunotherapy, innate immunity, mucosal immunology and the microbiota, regulation of the immune response, signalling in the immune system, transplantation, tumour immunology and immunotherapy, and vaccine development.