法国埃米珠单抗双配药回路对预算影响的估算:HemiValue 研究。

H Leleu, L Fraticelli, R Ajjouri, G Touvron, V Chamouard
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引用次数: 0

摘要

背景:A型血友病是一种罕见的出血性疾病,给患者及其护理人员带来经济负担。这项名为“HemiValue”的研究包括一个预算影响模型,以评估患者的利益和所有相关利益相关者转向双重配药的预算影响,从患者的角度和药房的角度比较成本和时间节省。方法:从患者的角度评估一年多来双配药循环的影响,评估包括与获得治疗相关的费用、差旅和等待时间,以及相关的收入损失。分析还包括医院药房(HP)、社区药房(CP)和生态考虑的观点。结果:在个体水平上,emicizumab在CP中的可用性每年减少了相当于3个工作日的获得这种治疗的时间。每年322欧元的直接成本差异表明,相对于家庭可用收入的成本比例从2.6%降至0.2%。这种减少在低收入家庭和那些居住在离HP 30分钟以上的家庭中更为明显。讨论:双重配药回路减少了获得emicizumab相关的财务和后勤负担。这些结果突出了创新配药模式的重要性,旨在缓解患者及其护理人员的限制,同时努力实现更大的可及性公平。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Estimation of the budget impact of the dual dispensing circuit of emicizumab in France: The HemiValue study.

Context: Hemophilia A is a rare bleeding disorder associated with an economic burden for patients and their caregivers. This study, called HemiValue, consists in a budget impact model to assess the benefits for patients and the budgetary impact of this shift to dual dispensing for all stakeholders involved, comparing the cost and time savings from the patients' perspective and from the pharmacies' perspective.

Methodology: The impact of the dual dispensing circuit over one year was evaluated from the patients' perspective, the evaluation included costs, travel and waiting times related to obtaining the treatment, as well as associated income losses. The analysis also included perspectives from hospital pharmacies (HP), community pharmacies (CP), and ecological considerations.

Results: On an individual level, the availability of emicizumab in CP reduced the time spent obtaining this treatment by the equivalent of 3 working days per year. The 322 euros difference in direct costs per year represents a reduction in the proportion of costs relative to the available income of families from 2.6% to 0.2%. This reduction was more pronounced for low-income households and those living more than 30 min from a HP.

Discussion: The dual dispensing circuit reduces the financial and logistical burdens associated with obtaining emicizumab. These results highlight the importance of innovative dispensing models that aim to ease constraints for patients and their caregivers while working towards greater equity in accessibility.

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