印度公共卫生机构门诊患者抗生素处方模式评价及药物合理性分析。

IF 1.4 4区 医学 Q4 IMMUNOLOGY
Vinay Modgil , Nusrat Shafiq , Amandeep Gondara , Rashmi Surial , Harpreet Singh , Vivek Karol , Manmeet Kaur , Helen Lambert , Neelam Taneja
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引用次数: 0

摘要

背景:抗生素耐药性(AMR)是一个重大的全球性健康问题,抗生素处方不当是一个主要因素。谨慎使用抗生素对于提高健康结果和减少抗生素耐药性至关重要。本研究评估了印度北部一家公共社区卫生机构为12,900名城市和农村人口提供抗生素处方的做法及其逻辑。方法:于2021年8月至2022年8月进行横断面研究,检查1219张门诊抗生素处方。数据包括药物种类,剂量,持续时间,对治疗标准的依从性,以及由ID专家和临床药理学家评估的基本原理。评估按照标准程序进行,包括NCDC和PGIMER的标准程序。对人口统计学、抗生素分类、WHO AWaRe分类、诊断和对基本药物清单(EDL)的依从性进行了评估。结果:处方中男性占45.9%,女性占54%,以20 ~ 40岁人群为主。阿莫西林+克拉维酸是最常使用的抗生素(27.2%),其次是甲硝唑(13.4%)和阿奇霉素(10.3%)。世卫组织AWaRe分类显示,49.7%的抗生素被归类为“可获得”,27.3%被归类为“观察”,没有任何抗生素被归类为“储备”。合理性检查表明,57%的尿路感染处方是合理的,但只有29%的呼吸道感染处方被认为是合理的。腹泻和呼吸道感染被认为是减少多余抗生素消耗的主要目标。结论:该研究强调了在门诊环境中加强抗生素处方协议的必要性。对医疗保健专业人员进行专门教育,改进处方监督,并遵守循证协议,对于促进明智地使用抗生素和解决抗生素耐药性至关重要。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
An evaluation of antibiotic prescription pattern and drug rationality analysis among outpatients at public health setting, India

Background

Antibiotic resistance (AMR) is a significant worldwide health problem, with inappropriate antibiotic prescription being a major contributing factor. Prudent antibiotic use is essential for enhancing health outcomes and reducing AMR. This study assesses antibiotic prescribing practices and their logic in a public community health facility catering to 12,900 urban and rural populations in North India.

Methods

Cross-sectional research was performed from August 2021 to August 2022, examining 1219 outpatient antibiotic prescriptions. The data encompassed medication kind, dose, duration, adherence to therapeutic criteria, and rationale evaluated by ID specialists and clinical pharmacologists. The evaluation was conducted in accordance with standard procedures, including those from NCDC and PGIMER. Demographics, antibiotic classifications, WHO AWaRe categories, diagnoses, and compliance with the essential drug list (EDL) were evaluated.

Results

The results indicated that 45.9 % of prescriptions were for males and 54 % for females, predominantly involving individuals aged 20–40 years. Amoxicillin + clavulanic acid (27.2 %) was the most often given antibiotic, followed by metronidazole (13.4 %) and azithromycin (10.3 %). The WHO AWaRe categorization revealed that 49.7 % of antibiotics were categorized as “Access,” 27.3 % as “Watch,” and none as “Reserve.” An examination of rationality indicated that 57 % of urinary tract infection prescriptions were justified, but just 29 % of respiratory tract infection prescriptions were deemed logical. Diarrhea and respiratory tract infections were recognized as primary targets for minimizing superfluous antibiotic consumption.

Conclusion

The research underscores the necessity for enhanced antibiotic prescription protocols in outpatient environments. Specialized education for healthcare professionals, improved prescription oversight, and compliance with evidence-based protocols are essential for fostering judicious antibiotic utilization and addressing AMR.
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来源期刊
CiteScore
2.20
自引率
0.00%
发文量
154
审稿时长
73 days
期刊介绍: Manuscripts of high standard in the form of original research, multicentric studies, meta analysis, are accepted. Current reports can be submitted as brief communications. Case reports must include review of current literature, clinical details, outcome and follow up. Letters to the editor must be a comment on or pertain to a manuscript already published in the IJMM or in relation to preliminary communication of a larger study. Review articles, Special Articles or Guest Editorials are accepted on invitation.
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