乌干达社区意识、筛查、诊断和治疗运动对结核病护理的影响。

IF 3.4 3区医学 Q2 INFECTIOUS DISEASES

International Journal of Tuberculosis and Lung Disease Pub Date : 2025-03-31 DOI:10.5588/ijtld.24.0488

R Mulebeke, C Chemutai, I Mubangizi, M Balina, J E Obwalatum, C Senyimba, J Izudi

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引用次数: 0

摘要

目标评估社区宣传、筛查、检测、诊断和治疗（CAST-TB）活动对结核病筛查、推测和诊断人数的影响。设计我们设计了一项准实验研究，并利用贝叶斯结构时间序列分析法对 24 个月（干预前 12 个月与干预期间 12 个月）内的反事实预测进行了分析。干预措施是 CAST-TB 运动。结果干预使结核病筛查人数增加了 36%（95% 可信区间 [CrI] 8.4-65，P = 0.005）（观察到的人数为 1,194,257 人，而预测的人数为 875,211 人），结核病筛查人数增加了 29%（95% 可信区间 [CrI] 5.3-52，P = 0.01），结核病筛查人数增加了 30%（95% 可信区间 [CrI] 8.4-65，P = 0.005），结核病筛查人数增加了 30%（95% 可信区间 [CrI] 8.4-65，P = 0.005），结核病筛查人数增加了 30%（95% 可信区间 [CrI] 8.4-65，P = 0.005）。结论CAST-TB运动提高了乌干达中部地区肺结核病筛查、推测和诊断的人数，支持了全国以及撒哈拉以南非洲地区的推广工作，因为这些地区的此类指标并不理想。

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Effect of community awareness, screening, diagnosis, and treatment campaigns on TB care in Uganda.

SETTINGEight districts in central Uganda with 105 health facilities.OBJECTIVETo evaluate the effectiveness of the community awareness, screening, testing, diagnosis, and treatment (CAST-TB) campaigns on the number of people screened for, presumed to have, and diagnosed with TB disease.DESIGNWe designed a quasi-experimental study and utilised Bayesian Structural Time-Series analysis for counterfactual predictions over 24 months (12 months before vs 12 months during intervention). The intervention was the CAST-TB campaigns. The outcomes included the number of people screened for, presumed to have, and diagnosed with TB disease.RESULTSThe intervention led to a 36% (95% credible interval [CrI] 8.4-65, P = 0.005) increase in the number of people screened for TB disease (1,194,257 observed vs 875,211 predicted), a 29% (95% CrI 5.3-52, P = 0.01) increase in the number of people presumed to have TB disease (25,784 observed vs 19,997 predicted), and a 49% (95% CrI 25-75) increase in the number of people diagnosed with TB disease (2,566 observed vs 1,719 counterfactual).CONCLUSIONCAST-TB campaigns improved the number of people screened for, presumed to have, and diagnosed with TB disease in central Uganda, supporting scale-up efforts nationally and across sub-Saharan Africa where such indicators are suboptimal..

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来源期刊

International Journal of Tuberculosis and Lung Disease 医学-传染病学

CiteScore

4.90

自引率

20.00%

发文量

266

审稿时长

2 months

期刊介绍： The International Journal of Tuberculosis and Lung Disease publishes articles on all aspects of lung health, including public health-related issues such as training programmes, cost-benefit analysis, legislation, epidemiology, intervention studies and health systems research. The IJTLD is dedicated to the continuing education of physicians and health personnel and the dissemination of information on tuberculosis and lung health world-wide.