{"title":"机器学习集成了基于氧化石墨烯的诊断、药物输送和分析方法,从而增强了癌症诊断的能力","authors":"Suparna Das, Hirak Mazumdar, Kamil Reza Khondakar, Ajeet Kaushik","doi":"10.1002/bmm2.12117","DOIUrl":null,"url":null,"abstract":"<p>Machine learning (ML) and nanotechnology interfacing are exploring opportunities for cancer treatment strategies. To improve cancer therapy, this article investigates the synergistic combination of Graphene Oxide (GO)-based devices with ML techniques. The production techniques and functionalization tactics used to modify the physicochemical characteristics of GO for specific drug delivery are explained at the outset of the investigation. GO is a great option for treating cancer because of its natural biocompatibility and capacity to absorb medicinal chemicals. Then, complicated biological data are analyzed using ML algorithms, which make it possible to identify the best medicine formulations and individualized treatment plans depending on each patient's particular characteristics. The study also looks at optimizing and predicting the interactions between GO carriers and cancer cells using ML. Predictive modeling helps ensure effective payload release and therapeutic efficacy in the design of customized drug delivery systems. Furthermore, tracking treatment outcomes in real time is made possible by ML algorithms, which permit adaptive modifications to therapy regimens. By optimizing medication doses and delivery settings, the combination of ML and GO in cancer therapy not only decreases adverse effects but also enhances treatment accuracy.</p>","PeriodicalId":100191,"journal":{"name":"BMEMat","volume":"3 1","pages":""},"PeriodicalIF":15.5000,"publicationDate":"2024-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/bmm2.12117","citationCount":"0","resultStr":"{\"title\":\"Machine learning integrated graphene oxide-based diagnostics, drug delivery, analytical approaches to empower cancer diagnosis\",\"authors\":\"Suparna Das, Hirak Mazumdar, Kamil Reza Khondakar, Ajeet Kaushik\",\"doi\":\"10.1002/bmm2.12117\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p>Machine learning (ML) and nanotechnology interfacing are exploring opportunities for cancer treatment strategies. To improve cancer therapy, this article investigates the synergistic combination of Graphene Oxide (GO)-based devices with ML techniques. The production techniques and functionalization tactics used to modify the physicochemical characteristics of GO for specific drug delivery are explained at the outset of the investigation. GO is a great option for treating cancer because of its natural biocompatibility and capacity to absorb medicinal chemicals. Then, complicated biological data are analyzed using ML algorithms, which make it possible to identify the best medicine formulations and individualized treatment plans depending on each patient's particular characteristics. The study also looks at optimizing and predicting the interactions between GO carriers and cancer cells using ML. Predictive modeling helps ensure effective payload release and therapeutic efficacy in the design of customized drug delivery systems. Furthermore, tracking treatment outcomes in real time is made possible by ML algorithms, which permit adaptive modifications to therapy regimens. By optimizing medication doses and delivery settings, the combination of ML and GO in cancer therapy not only decreases adverse effects but also enhances treatment accuracy.</p>\",\"PeriodicalId\":100191,\"journal\":{\"name\":\"BMEMat\",\"volume\":\"3 1\",\"pages\":\"\"},\"PeriodicalIF\":15.5000,\"publicationDate\":\"2024-09-28\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://onlinelibrary.wiley.com/doi/epdf/10.1002/bmm2.12117\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"BMEMat\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://onlinelibrary.wiley.com/doi/10.1002/bmm2.12117\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"BMEMat","FirstCategoryId":"1085","ListUrlMain":"https://onlinelibrary.wiley.com/doi/10.1002/bmm2.12117","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
摘要
机器学习(ML)与纳米技术的结合为癌症治疗策略带来了新的机遇。为了改善癌症治疗,本文研究了基于石墨烯氧化物(GO)的设备与 ML 技术的协同组合。文章一开始就解释了用于改变 GO 理化特性以实现特定药物输送的生产技术和功能化策略。GO 具有天然的生物相容性和吸收药物化学物质的能力,是治疗癌症的最佳选择。然后,利用 ML 算法对复杂的生物数据进行分析,从而根据每位患者的具体特征确定最佳药物配方和个性化治疗方案。这项研究还着眼于利用 ML 优化和预测 GO 载体与癌细胞之间的相互作用。预测建模有助于确保在设计定制药物输送系统时有效释放有效载荷并提高疗效。此外,利用 ML 算法还可以实时跟踪治疗结果,从而对治疗方案进行自适应修改。通过优化药物剂量和给药设置,ML 和 GO 在癌症治疗中的结合不仅能减少不良反应,还能提高治疗的准确性。
Machine learning integrated graphene oxide-based diagnostics, drug delivery, analytical approaches to empower cancer diagnosis
Machine learning (ML) and nanotechnology interfacing are exploring opportunities for cancer treatment strategies. To improve cancer therapy, this article investigates the synergistic combination of Graphene Oxide (GO)-based devices with ML techniques. The production techniques and functionalization tactics used to modify the physicochemical characteristics of GO for specific drug delivery are explained at the outset of the investigation. GO is a great option for treating cancer because of its natural biocompatibility and capacity to absorb medicinal chemicals. Then, complicated biological data are analyzed using ML algorithms, which make it possible to identify the best medicine formulations and individualized treatment plans depending on each patient's particular characteristics. The study also looks at optimizing and predicting the interactions between GO carriers and cancer cells using ML. Predictive modeling helps ensure effective payload release and therapeutic efficacy in the design of customized drug delivery systems. Furthermore, tracking treatment outcomes in real time is made possible by ML algorithms, which permit adaptive modifications to therapy regimens. By optimizing medication doses and delivery settings, the combination of ML and GO in cancer therapy not only decreases adverse effects but also enhances treatment accuracy.