Comparative evaluation of ozonized water versus normal saline irrigation with mechanical debridement in chronic periodontitis patients – A clinical study

Background

Ozone therapy is a rather novel approach for managing many diseases, encompassing oral disorders such as tooth caries and periodontal disease. It possesses the ability to disrupt microbial cell walls, resulting in rapid cell lysis. Moreover, characteristics of ozone such as anti-inflammation, stimulation and modulation of immunity contribute to mitigating the host response aspect of periodontal disease.

Objective

To assess the adjunctive advantages of irrigation of ozonized water in conjunction with mechanical debridement for the treatment of periodontitis.

Methodology

50 patients with chronic periodontitis and pocket probing depth ≥4 have been divided into 2 groups i.e. Test (n = 25) and control groups (n = 25). While the control group was administered normal saline irrigation and mechanical debridement, the test group was given ozonized water irrigation. Evaluations were conducted at baseline and four weeks following treatment to determine the plaque score, bleeding score, pocket probing depth, and clinical attachment level.

Results

Clinical measures such as clinical attachment level, pocket probing depth, bleeding index, and plaque index, significantly improved with adjunctive ozone water irrigation. The frequency of sites with bleeding on probing that had a pocket depth ≥4 mm was significantly reduced as a result of ozone water irrigation.

Conclusion

Ozone irrigation alongside nonsurgical periodontal therapy offers adjunctive benefits by reducing clinical parameters.