心理弹性、心血管疾病和死亡率——来自德国古腾堡健康研究的见解

IF 3.5 2区医学 Q2 PSYCHIATRY

Journal of Psychosomatic Research Pub Date : 2025-03-28 DOI:10.1016/j.jpsychores.2025.112116

Omar Hahad , Jasmin Ghaemi Kerahrodi , Elmar Brähler , Klaus Lieb , Donya Gilan , Daniela Zahn , Katja Petrowski , Anna Celine Reinwarth , Konstantin Kontohow-Beckers , Alexander K. Schuster , Markus Schepers , Karl Lackner , Peter R. Galle , Stavros Konstantinides , Philipp Wild , Andreas Daiber , Matthias Michal , Thomas Münzel , Manfred Beutel

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引用次数: 0

摘要

目的心理困扰与心血管疾病（CVD）和死亡率升高相关，而心理弹性可能具有保护作用。然而，关于这些关系的证据仍然有限。本研究旨在检查心理弹性、心血管疾病和全因死亡率之间的关系。方法对来自德国古腾堡健康研究的12675名参与者的数据进行分析。采用简易弹性应对量表（BRCS）评估心理弹性。心血管疾病患病率和死亡率数据来自医疗记录和登记更新。Logistic和Cox回归分析考察了适应力、心血管疾病和死亡率之间的关系，并对社会人口统计学、生活方式和临床因素进行了调整。结果从横截面上看，较低的恢复力与较高的心血管疾病发生率相关（比值比（OR） 1.030, 95%可信区间[CI] 1.009-1.051）。与高恢复力的参与者相比，低恢复力的参与者患心血管疾病的几率高出38%，外周动脉疾病的几率高出61%。纵向上，低恢复力与最高的全因死亡风险相关(log-rank检验，p <；0.0001)。校正混杂因素后，这种关联在Cox模型中仍然显著（风险比（HR） 1.362, 95% CI 1.002-1.852）。结论心理恢复能力较慢与心血管疾病患病率和全因死亡率升高有关。这些发现强调了恢复力作为心血管风险评估和干预的潜在目标。在临床实践中纳入弹性措施可能有助于识别弱势个体，他们可以从增强适应性应对、改善心血管和整体健康结果的策略中受益。

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Psychological resilience, cardiovascular disease, and mortality – Insights from the German Gutenberg Health Study

Objective

Psychological distress is associated with a higher risk of cardiovascular disease (CVD) and mortality, whereas psychological resilience may confer a protective effect. However, evidence on these relationships remains limited. This study aimed to examine the associations between psychological resilience, CVD, and all-cause mortality within a large general population cohort.

Methods

Data from 12,675 participants in the German Gutenberg Health Study were analyzed. Psychological resilience was assessed using the Brief Resilient Coping Scale (BRCS). CVD prevalence and mortality data were obtained from medical records and registry updates. Logistic and Cox regression analyses examined the associations between resilience, CVD, and mortality, with adjustments for socio-demographics, lifestyle, and clinical factors.

Results

Cross-sectionally, lower resilience was linked to higher odds of any CVD (odds ratio (OR) 1.030, 95 % confidence interval [CI] 1.009–1.051). Participants with low resilience had 38 % higher odds of CVD and 61 % higher odds of peripheral artery disease compared to those with high resilience. Longitudinally, low resilience was associated with the highest all-cause mortality risk (log-rank test, p < 0.0001). This association remained significant in Cox models after adjusting for confounders (hazard ratio (HR) 1.362, 95 % CI 1.002–1.852).

Conclusions

Lower psychological resilience is associated with increased CVD prevalence and all-cause mortality. These findings highlight resilience as a potential target for cardiovascular risk assessment and intervention. Incorporating resilience measures in clinical practice may help identify vulnerable individuals who could benefit from strategies to enhance adaptive coping, improving cardiovascular and overall health outcomes.

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来源期刊

Journal of Psychosomatic Research 医学-精神病学

CiteScore

7.40

自引率

6.40%

发文量

314

审稿时长

6.2 weeks

期刊介绍： The Journal of Psychosomatic Research is a multidisciplinary research journal covering all aspects of the relationships between psychology and medicine. The scope is broad and ranges from basic human biological and psychological research to evaluations of treatment and services. Papers will normally be concerned with illness or patients rather than studies of healthy populations. Studies concerning special populations, such as the elderly and children and adolescents, are welcome. In addition to peer-reviewed original papers, the journal publishes editorials, reviews, and other papers related to the journal''s aims.