人际关系问题是成人抑郁症治疗效果的预测因素：个体参与者数据荟萃分析

IF 13.7 1区心理学 Q1 PSYCHOLOGY, CLINICAL

Clinical Psychology Review Pub Date : 2025-03-27 DOI:10.1016/j.cpr.2025.102570

Juan Martín Gómez Penedo , Manuel Meglio , Christoph Flückiger , Frederik J. Wienicke , Jasmijn Breunese , Marco Menchetti , Paola Rucci , Robert Johansson , Joel M. Town , Allan A. Abbass , Peter Lilliengren , R. Michael Bagby , Lena C. Quilty , Lotte H.J.M. Lemmens , Suzanne C. van Bronswijk , Michael Barkham , William B. Stiles , Gillian E. Hardy , Peter Fonagy , Patrick Luyten , Ellen Driessen

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This meta-analytic strategy can reduce variability by standardizing data analysis across primary studies.</div></div><div><h3>Methods</h3><div>We included studies examining the efficacy of five treatments for adult depression and assessing interpersonal problems at baseline. One-stage IPD-MA was conducted with three-level mixed models to determine whether baseline overall interpersonal distress, agency, and communion predicted depressive symptom level at post-treatment, 12-month, and 24-month follow-up. The moderating effect of treatment type was also investigated.</div></div><div><h3>Results</h3><div>Ten studies (including <em>n</em> = 1282 participants) met inclusion criteria. 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Interpersonal problems as a predictor of treatment outcome in adult depression: An individual participant data meta-analysis

Objectives

Interpersonal problems are a fundamental feature of depression, but study-level meta-analyses of their association with treatment outcome have been limited by heterogeneity in primary studies' analyses and reported results. We conducted a pre-registered individual participant data meta-analysis (IPD-MA) to examine this relationship for adult depression. This meta-analytic strategy can reduce variability by standardizing data analysis across primary studies.

Methods

We included studies examining the efficacy of five treatments for adult depression and assessing interpersonal problems at baseline. One-stage IPD-MA was conducted with three-level mixed models to determine whether baseline overall interpersonal distress, agency, and communion predicted depressive symptom level at post-treatment, 12-month, and 24-month follow-up. The moderating effect of treatment type was also investigated.

Results

Ten studies (including n = 1282 participants) met inclusion criteria. Only overall interpersonal distress was negatively related with outcomes at post-treatment (γ = 0.11, CI₉₅[0.06, 0.16], r = 0.11), 12-month follow-up (γ = 0.17, CI₉₅[0.08, 0.25], r = 0.17), and 24-month follow-up (γ = 0.16, CI₉₅[0.05, 0.26], r = 0.16), indicative of smaller effect sizes. The agency and communion dimensions were not significantly related to outcome. Treatment type did not significantly moderate interpersonal distress-outcome associations.

Discussion

Results show a small association between patient baseline overall interpersonal distress and subsequent depression treatment outcome in brief treatments for depression. Further studies might require to account for therapist effects.

Registration number osf.io/u46t7

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来源期刊

Clinical Psychology Review PSYCHOLOGY, CLINICAL-

CiteScore

23.10

自引率

1.60%

发文量

期刊介绍： Clinical Psychology Review serves as a platform for substantial reviews addressing pertinent topics in clinical psychology. Encompassing a spectrum of issues, from psychopathology to behavior therapy, cognition to cognitive therapies, behavioral medicine to community mental health, assessment, and child development, the journal seeks cutting-edge papers that significantly contribute to advancing the science and/or practice of clinical psychology. While maintaining a primary focus on topics directly related to clinical psychology, the journal occasionally features reviews on psychophysiology, learning therapy, experimental psychopathology, and social psychology, provided they demonstrate a clear connection to research or practice in clinical psychology. Integrative literature reviews and summaries of innovative ongoing clinical research programs find a place within its pages. However, reports on individual research studies and theoretical treatises or clinical guides lacking an empirical base are deemed inappropriate for publication.