InnovEyes 消融轮廓中角膜中央基质厚度降低的可预测性：一项回顾性研究。

IF 3.1 3区医学 Q2 ONCOLOGY

Photodiagnosis and Photodynamic Therapy Pub Date : 2025-03-24 DOI:10.1016/j.pdpdt.2025.104570

Shimin Tan , Yimeng Fan , Xindi Wang, Yu Zhang, Yunpeng Li, Xiaojuan Fan, Zhao Liu, Shengjian Mi, Qianyan Kang

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Planned and achieved central CST, PAD and increase of central CET were compared.</div><div>Results: The achieved central CST reduction was 113.60 ± 21.88 μm in the InnovEyes group, which was not significantly different from the planned (108.70 ± 19.87 μm, <em>P</em> = 0.075). There was a strong correlation between the achieved central CST reduction and the planned reduction in the InnovEyes group (R<sup>2</sup> = 0.884, <em>P</em> < 0.001), which was stronger than in the Custom-Q group (R<sup>2</sup> = 0.861, <em>P</em> < 0.001). The PAD of central CST reduction was -4.87 ± 8.17 μm and -4.76 ± 9.75 μm for the InnovEyes and Custom-Q groups, respectively (<em>P</em> = 0.966). The increase of central CET was 3.29 ± 3.97 μm in InnovEyes group and 4.39 ± 4.84 μm in Custom-Q group, with no significant difference (<em>P</em> = 0.064).</div><div>Conclusions: The InnovEyes ablation profile demonstrates good predictability of the central CST reduction, ensuring the safety of this novel profile. 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Predictability of central corneal stromal thickness reduction in InnovEyes ablation profile: A retrospective study

Objective: To evaluate the predictability of the central corneal stromal thickness (CST) reduction in InnovEyes ablation profile.

Methods: The retrospective study included 118 eyes (61 patients) who underwent surgeries based on InnovEyes profile and 117 eyes (67 patients) based on the Custom-Q. The central CST, the central corneal thickness (CT) and the central corneal epithelial thickness (CET) were measured using anterior segment optical coherence tomography (AS-OCT) preoperatively and postoperatively over 3 months. The planned-achieved thickness (PAD) was calculated. Planned and achieved central CST, PAD and increase of central CET were compared.

Results: The achieved central CST reduction was 113.60 ± 21.88 μm in the InnovEyes group, which was not significantly different from the planned (108.70 ± 19.87 μm, P = 0.075). There was a strong correlation between the achieved central CST reduction and the planned reduction in the InnovEyes group (R² = 0.884, P < 0.001), which was stronger than in the Custom-Q group (R² = 0.861, P < 0.001). The PAD of central CST reduction was -4.87 ± 8.17 μm and -4.76 ± 9.75 μm for the InnovEyes and Custom-Q groups, respectively (P = 0.966). The increase of central CET was 3.29 ± 3.97 μm in InnovEyes group and 4.39 ± 4.84 μm in Custom-Q group, with no significant difference (P = 0.064).

Conclusions: The InnovEyes ablation profile demonstrates good predictability of the central CST reduction, ensuring the safety of this novel profile. Besides, the InnovEyes profile may have taken postoperative corneal epithelial remodeling into consideration, and provided an enhanced pre-compensation.

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来源期刊

Photodiagnosis and Photodynamic Therapy ONCOLOGY-

CiteScore

5.80

自引率

24.20%

发文量

509

审稿时长

50 days

期刊介绍： Photodiagnosis and Photodynamic Therapy is an international journal for the dissemination of scientific knowledge and clinical developments of Photodiagnosis and Photodynamic Therapy in all medical specialties. The journal publishes original articles, review articles, case presentations, "how-to-do-it" articles, Letters to the Editor, short communications and relevant images with short descriptions. All submitted material is subject to a strict peer-review process.