首次精神病发作后9年精神疾病医疗保健使用的患病率和预测因素:瑞典国家队列研究

IF 4.9 0 PSYCHIATRY
Donna van Deursen, Ellenor Mittendorfer-Rutz, Heidi Taipale, Emma Pettersson, Philip McGuire, Paolo Fusar-Poli, Dan W Joyce, Nikolai Albert, Annette Erlangsen, Meredete Nordentoft, Carsten Hjorthøj, Simon Cervenka, Alexis E Cullen
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引用次数: 0

摘要

背景:众所周知,精神障碍在病程和预后方面表现出异质性,但很少有研究调查了长期的医疗保健使用。目的:确定首次精神病发作(FEP)后9年精神障碍医疗保健使用的患病率和预测因素。方法:使用国家登记册对2006年至2013年期间年龄在18-35岁之间患有FEP的所有瑞典居民进行识别。在9年随访的每一年确定12个月期间的二级医疗保健使用率,并根据主要诊断进行分类(精神障碍与其他精神障碍、无精神障碍与审查)。使用多项逻辑回归模型检查基线特征与9年医疗保健使用之间的关联,并为每个预测变量导出四个结果组的预测概率和95% ci。结果:在7733例FEP患者中,在9年随访中,31.7%的患者在二级医疗机构接受过精神障碍治疗,24.1%的患者接受过其他精神障碍治疗,35.7%的患者没有接受过精神障碍医疗服务,8.5%的患者因死亡/移民而被筛查。首次诊断为精神分裂症的患者在9年时因精神障碍而进行二次医疗的最高概率相关(0.50,95% CI(0.46至0.54)),其次是首次诊断时住院治疗(0.37,95% CI(0.35至0.38))。结论:尽管56%的FEP患者在9年后在二级医疗机构接受了精神障碍治疗,但相当大比例的患者接受了非精神障碍治疗。临床意义:初次诊断为精神分裂症的个体,在住院环境中接受首次诊断,可能需要更多的强化治疗以促进缓解和恢复。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Prevalence and predictors of healthcare use for psychiatric disorders at 9 years after a first episode of psychosis: a Swedish national cohort study.

Prevalence and predictors of healthcare use for psychiatric disorders at 9 years after a first episode of psychosis: a Swedish national cohort study.

Prevalence and predictors of healthcare use for psychiatric disorders at 9 years after a first episode of psychosis: a Swedish national cohort study.

Background: Psychotic disorders are known to exhibit heterogeneity with regards to illness course and prognosis, yet few studies have examined long-term healthcare use.

Objective: To determine the prevalence and predictors of healthcare use for psychiatric disorders at 9 years after the first episode of psychosis (FEP).

Methods: National registers were used to identify all Swedish residents aged 18-35 years with FEP between 2006 and 2013. The 12-month period-prevalence of secondary healthcare use was determined at each year of the 9-year follow-up, categorised according to main diagnosis (psychotic disorder vs other psychiatric disorder vs none vs censored). Multinomial logistic regression models were used to examine associations between baseline characteristics and healthcare use at 9 years and derive predicted probabilities and 95% CIs for the four outcome groups, for each predictor variable.

Findings: Among 7733 individuals with FEP, 31.7% were treated in secondary healthcare for psychotic disorders at the 9-year follow-up, 24.1% were treated for other psychiatric disorders, 35.7% did not use healthcare services for psychiatric disorders and 8.5% were censored due to death/emigration. Having an initial diagnosis of schizophrenia was associated with the highest probability of secondary healthcare use for psychotic disorder at 9 years (0.50, 95% CI (0.46 to 0.54)] followed by inpatient treatment at first diagnosis (0.37, 95% CI (0.35 to 0.38)).

Conclusion: Although 56% of individuals with FEP were treated for psychiatric disorders in secondary healthcare 9 years later, a substantial proportion were treated for non-psychotic disorders.

Clinical implications: Individuals with an initial diagnosis of schizophrenia, who received their first diagnosis in inpatient settings, may need more intensive treatment to facilitate remission and recovery.

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