育龄妇女偏头痛患病率的全球、区域和国家时间趋势:基于2021年全球疾病负担研究的最新年龄-时期队列分析

IF 3.2 3区 医学 Q2 CLINICAL NEUROLOGY
Ben Hu, Xiaohan Qiu, Yan Wang, Xing Wei, Jun Feng, Linlin Hou
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引用次数: 0

摘要

前言:全面评估1992年至2021年全球、地区和国家层面育龄妇女(WCBA)偏头痛患病率的时间趋势,特别强调检查不同社会人口指数(SDI)区域的患病率模式与年龄、时期和出生队列效应之间的关系。方法:我们对2021年全球疾病负担研究的数据进行了二次分析。提取WCBA的偏头痛患病率估计值和95%不确定区间(UI)。采用年龄-时期-队列模型来估计净漂移(主要结局)、局部漂移、年龄/时期/队列相对风险(次要结局)。结果:2021年全球伴有偏头痛的WCBA患者数量达到493,937,856.01例(95% UI: 420,683,360.54 ~ 577,874,600.76)。负担最重的是印度(9570万)和中国(6810万),两国合计占全球流行率的很大比例。结论:尽管WCBA的全球偏头痛患病率保持稳定,但在高、中高和中等SDI地区,年轻年龄组(15-19岁)的不利上升趋势,以及时期/队列风险的恶化,突出了当前预防和管理方面的差距。随着时间的推移,改进的策略有望降低较年轻的出生队列和所有年龄组的风险。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Global, regional and national temporal trends in prevalence for migraine in women of childbearing age: an updated age-period-cohort analysis based on Global Burden of Disease Study 2021.

Introduction: To provide a comprehensive assessment of temporal trends in migraine prevalence among women of childbearing age (WCBA) at global, regional and national levels from 1992 to 2021, with particular emphasis on examining the associations between prevalence patterns and age, period and birth cohort effects across different sociodemographic index (SDI) regions.

Methods: We conducted a secondary analysis of data from the Global Burden of Disease Study 2021. Migraine prevalence estimates and 95% uncertainty intervals (UI) for WCBA were extracted. An age-period-cohort model was employed to estimate the net drift (primary outcomes), local drift, age/period/cohort relative risks (secondary outcomes).

Results: The global number of WCBA with migraine reached 493,937,856.01 (95% UI: 420,683,360.54 to 577,874,600.76) in 2021. The highest burden was found in India (95.7 million) and China (68.1 million), together accounting for substantial proportion of global prevalence. The global net drift showed minimal change 0.01% (95% CI: 0.00-0.02, p<0.01) per year, with variations across sociodemographic index (SDI) regions ranging from -0.03% per year, (95% CI: -0.04 to -0.02, p<0.01) in low-middle SDI regions to 0.16% (95% CI: 0.15-0.17, p<0.01) in middle-SDI regions. Local drift analysis reveals that migraine prevalence increases across young age groups (15-19 years) in high-SDI regions, while lower-SDI regions generally display stable rates. Globally, increases in migraine prevalence among young adults within WCBA are notably persistent. Across SDI regions, age effects follow similar patterns, with risk rising with age and peaking in the mid-reproductive years (ages 30-39). Over time, period risks and unfavorable trends across successive birth cohorts have intensified, particularly in high, high-middle, and middle-SDI regions.

Conclusion: Although global migraine prevalence among WCBA remains stable, an unfavorable upward trend in younger age groups (15-19 years) in high, high-middle, and middle SDI regions, alongside worsening period/cohort risks, highlights current gaps in prevention and management. Improved strategies are expected to reduce risks for younger birth cohorts and all age groups over time.

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来源期刊
Neuroepidemiology
Neuroepidemiology 医学-公共卫生、环境卫生与职业卫生
CiteScore
9.90
自引率
1.80%
发文量
49
审稿时长
6-12 weeks
期刊介绍: ''Neuroepidemiology'' is the only internationally recognised peer-reviewed periodical devoted to descriptive, analytical and experimental studies in the epidemiology of neurologic disease. The scope of the journal expands the boundaries of traditional clinical neurology by providing new insights regarding the etiology, determinants, distribution, management and prevention of diseases of the nervous system.
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