{"title":"赋予未来力量:恢复 HIV 感染儿童的 T 细胞应答。","authors":"John Patrick Toledo","doi":"10.1093/infdis/jiaf160","DOIUrl":null,"url":null,"abstract":"<p><p>This study examines how children with HIV recover mycobacteria-specific T cell responses after six months of antiretroviral therapy (ART). Persistent deficiencies raise concerns about tuberculosis susceptibility despite elevated Th1 CD4 T cells, emphasizing the necessity of focused treatments and continuous health empowerment in susceptible juvenile populations.</p>","PeriodicalId":50179,"journal":{"name":"Journal of Infectious Diseases","volume":" ","pages":""},"PeriodicalIF":5.0000,"publicationDate":"2025-03-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Empowering Futures: Restoring T Cell Responses in Children Living with HIV.\",\"authors\":\"John Patrick Toledo\",\"doi\":\"10.1093/infdis/jiaf160\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>This study examines how children with HIV recover mycobacteria-specific T cell responses after six months of antiretroviral therapy (ART). Persistent deficiencies raise concerns about tuberculosis susceptibility despite elevated Th1 CD4 T cells, emphasizing the necessity of focused treatments and continuous health empowerment in susceptible juvenile populations.</p>\",\"PeriodicalId\":50179,\"journal\":{\"name\":\"Journal of Infectious Diseases\",\"volume\":\" \",\"pages\":\"\"},\"PeriodicalIF\":5.0000,\"publicationDate\":\"2025-03-26\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of Infectious Diseases\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1093/infdis/jiaf160\",\"RegionNum\":2,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"IMMUNOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Infectious Diseases","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1093/infdis/jiaf160","RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"IMMUNOLOGY","Score":null,"Total":0}
Empowering Futures: Restoring T Cell Responses in Children Living with HIV.
This study examines how children with HIV recover mycobacteria-specific T cell responses after six months of antiretroviral therapy (ART). Persistent deficiencies raise concerns about tuberculosis susceptibility despite elevated Th1 CD4 T cells, emphasizing the necessity of focused treatments and continuous health empowerment in susceptible juvenile populations.
期刊介绍:
Published continuously since 1904, The Journal of Infectious Diseases (JID) is the premier global journal for original research on infectious diseases. The editors welcome Major Articles and Brief Reports describing research results on microbiology, immunology, epidemiology, and related disciplines, on the pathogenesis, diagnosis, and treatment of infectious diseases; on the microbes that cause them; and on disorders of host immune responses. JID is an official publication of the Infectious Diseases Society of America.