{"title":"氟生物活性玻璃与氟化钠牙膏在原牙釉质损伤再矿化中的应用对比分析。","authors":"Chanikarn Poopirom, Veeritta Yimcharoen, Praphasri Rirattanapong","doi":"10.4103/jispcd.jispcd_42_24","DOIUrl":null,"url":null,"abstract":"<p><strong>Aim: </strong>This study aimed to compare the remineralization effect of a fluoride bioactive glass (FBG) toothpaste with different concentrations of sodium fluoride toothpaste based on the surface microhardness (SMH) in artificial enamel carious lesions of primary teeth.</p><p><strong>Materials and methods: </strong>Fifty sound primary incisors were allocated into five groups (<i>n</i> = 10): Group DI (deionized water); Group FBG (Biomin® F); Group 500 ppmF (Jordan®); Group 1000 ppmF (Kodomo®); and Group 1500 ppmF (Systema®). The teeth were fixed in self-cure acrylic resin blocks, and artificial carious lesions were created by immersing them in a demineralizing solution (D1) for 4 days. The specimens underwent 7-day pH-cycling and were treated with the provided toothpaste twice daily. The SMH was examined at baseline, after artificial caries induction, and after pH-cycling. The data were calculated as the percentage SMH recovery (%SMHR). One-way ANOVA, <i>post hoc</i> tests (Tukey HSD or Games-Howell tests), and regression analysis were used to analyze the results with a significance level of 0.05.</p><p><strong>Results: </strong>The %SMHR of the four groups (different toothpastes) was significantly higher than that of the control group, with all toothpaste groups showing a positive effect on %SMHR (<i>P</i> value < 0.001). The highest %SMHR was observed for 1500 ppmF and FBG, with no significant difference (<i>P</i> value = 0.984). Both had the most significant positive effects on %SMHR, with <i>β</i> coefficients of 1.076 and 1.002, respectively.</p><p><strong>Conclusion: </strong>The remineralization effect of the FBG toothpaste was comparable to that of 1500 ppmF toothpaste and had a greater efficacy than those of 500 and 1000 ppmF based on SMH testing on enamel carious lesions in primary teeth. It offers an effective alternative option for toothpaste with a lower risk of systemic fluoride toxicity, offering a safer, effective option for caries prevention in children.</p>","PeriodicalId":47247,"journal":{"name":"Journal of International Society of Preventive and Community Dentistry","volume":"15 1","pages":"34-41"},"PeriodicalIF":1.4000,"publicationDate":"2025-02-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11940512/pdf/","citationCount":"0","resultStr":"{\"title\":\"Comparative Analysis of Application of Fluoride Bioactive Glass and Sodium Fluoride Toothpastes for Remineralization of Primary Tooth Enamel Lesions.\",\"authors\":\"Chanikarn Poopirom, Veeritta Yimcharoen, Praphasri Rirattanapong\",\"doi\":\"10.4103/jispcd.jispcd_42_24\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Aim: </strong>This study aimed to compare the remineralization effect of a fluoride bioactive glass (FBG) toothpaste with different concentrations of sodium fluoride toothpaste based on the surface microhardness (SMH) in artificial enamel carious lesions of primary teeth.</p><p><strong>Materials and methods: </strong>Fifty sound primary incisors were allocated into five groups (<i>n</i> = 10): Group DI (deionized water); Group FBG (Biomin® F); Group 500 ppmF (Jordan®); Group 1000 ppmF (Kodomo®); and Group 1500 ppmF (Systema®). The teeth were fixed in self-cure acrylic resin blocks, and artificial carious lesions were created by immersing them in a demineralizing solution (D1) for 4 days. The specimens underwent 7-day pH-cycling and were treated with the provided toothpaste twice daily. The SMH was examined at baseline, after artificial caries induction, and after pH-cycling. The data were calculated as the percentage SMH recovery (%SMHR). One-way ANOVA, <i>post hoc</i> tests (Tukey HSD or Games-Howell tests), and regression analysis were used to analyze the results with a significance level of 0.05.</p><p><strong>Results: </strong>The %SMHR of the four groups (different toothpastes) was significantly higher than that of the control group, with all toothpaste groups showing a positive effect on %SMHR (<i>P</i> value < 0.001). The highest %SMHR was observed for 1500 ppmF and FBG, with no significant difference (<i>P</i> value = 0.984). Both had the most significant positive effects on %SMHR, with <i>β</i> coefficients of 1.076 and 1.002, respectively.</p><p><strong>Conclusion: </strong>The remineralization effect of the FBG toothpaste was comparable to that of 1500 ppmF toothpaste and had a greater efficacy than those of 500 and 1000 ppmF based on SMH testing on enamel carious lesions in primary teeth. It offers an effective alternative option for toothpaste with a lower risk of systemic fluoride toxicity, offering a safer, effective option for caries prevention in children.</p>\",\"PeriodicalId\":47247,\"journal\":{\"name\":\"Journal of International Society of Preventive and Community Dentistry\",\"volume\":\"15 1\",\"pages\":\"34-41\"},\"PeriodicalIF\":1.4000,\"publicationDate\":\"2025-02-26\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11940512/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of International Society of Preventive and Community Dentistry\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.4103/jispcd.jispcd_42_24\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2025/1/1 0:00:00\",\"PubModel\":\"eCollection\",\"JCR\":\"Q3\",\"JCRName\":\"DENTISTRY, ORAL SURGERY & MEDICINE\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of International Society of Preventive and Community Dentistry","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.4103/jispcd.jispcd_42_24","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/1/1 0:00:00","PubModel":"eCollection","JCR":"Q3","JCRName":"DENTISTRY, ORAL SURGERY & MEDICINE","Score":null,"Total":0}
Comparative Analysis of Application of Fluoride Bioactive Glass and Sodium Fluoride Toothpastes for Remineralization of Primary Tooth Enamel Lesions.
Aim: This study aimed to compare the remineralization effect of a fluoride bioactive glass (FBG) toothpaste with different concentrations of sodium fluoride toothpaste based on the surface microhardness (SMH) in artificial enamel carious lesions of primary teeth.
Materials and methods: Fifty sound primary incisors were allocated into five groups (n = 10): Group DI (deionized water); Group FBG (Biomin® F); Group 500 ppmF (Jordan®); Group 1000 ppmF (Kodomo®); and Group 1500 ppmF (Systema®). The teeth were fixed in self-cure acrylic resin blocks, and artificial carious lesions were created by immersing them in a demineralizing solution (D1) for 4 days. The specimens underwent 7-day pH-cycling and were treated with the provided toothpaste twice daily. The SMH was examined at baseline, after artificial caries induction, and after pH-cycling. The data were calculated as the percentage SMH recovery (%SMHR). One-way ANOVA, post hoc tests (Tukey HSD or Games-Howell tests), and regression analysis were used to analyze the results with a significance level of 0.05.
Results: The %SMHR of the four groups (different toothpastes) was significantly higher than that of the control group, with all toothpaste groups showing a positive effect on %SMHR (P value < 0.001). The highest %SMHR was observed for 1500 ppmF and FBG, with no significant difference (P value = 0.984). Both had the most significant positive effects on %SMHR, with β coefficients of 1.076 and 1.002, respectively.
Conclusion: The remineralization effect of the FBG toothpaste was comparable to that of 1500 ppmF toothpaste and had a greater efficacy than those of 500 and 1000 ppmF based on SMH testing on enamel carious lesions in primary teeth. It offers an effective alternative option for toothpaste with a lower risk of systemic fluoride toxicity, offering a safer, effective option for caries prevention in children.
期刊介绍：
It is a journal aimed for research, scientific facts and details covering all specialties of dentistry with a good determination for exploring and sharing the knowledge in the medical and dental fraternity. The scope is therefore huge covering almost all streams of dentistry - starting from original studies, systematic reviews, narrative reviews, very unique case reports. Journal scope is not limited to these subjects and is more wider covering all specialities of dentistry follows: -Preventive and Community dentistry (Dental public health)- Endodontics- Oral and maxillofacial pathology- Oral and maxillofacial radiology- Oral and maxillofacial surgery (also called oral surgery)- Orthodontics and dentofacial orthopedics- Periodontology (also called periodontics)- Pediatric dentistry (also called pedodontics)- Prosthodontics (also called prosthetic dentistry)- Oral medicine- Special needs dentistry (also called special care dentistry)- Oral Biology- Forensic odontology- Geriatric dentistry or Geriodontics- Preventive and Social Medicine (Public health)- Our journal appreciates research articles pertaining with advancement of dentistry, preventive and community dentistry including oral epidemiology, oral health services research, oral health education and promotion, behavioral sciences related to dentistry, dental jurisprudence, ethics and oral health, economics, and quality assessment, recent advances in preventive dentistry and community dentistry.
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