Islam Basuny Abd Elhamid Abo Salh, Emad Boriqaa Add El-Salam, Amgad A Ezzat, Mohamed Aboshama, Ahmed Fathey Elhagali
{"title":"三种不同纳米颗粒改性3d打印义齿树脂的抗菌效果：体外研究。","authors":"Islam Basuny Abd Elhamid Abo Salh, Emad Boriqaa Add El-Salam, Amgad A Ezzat, Mohamed Aboshama, Ahmed Fathey Elhagali","doi":"10.4103/jispcd.jispcd_53_24","DOIUrl":null,"url":null,"abstract":"<p><strong>Aim: </strong>This study aimed to determine the antibacterial effectiveness of adding zirconia nanoparticles (NPs; ZrO<sub>2</sub>NPs), silver NPs (AgNPs), and titanium dioxide NPs (TiO<sub>2</sub>NPs) in various concentrations to three-dimensional (3D)-printed denture resin against <i>Candida Albicans</i>, <i>Streptococcus pyogenes</i>, and <i>Staphylococcus aureus</i>, this study was carried out.</p><p><strong>Materials and methods: </strong>The antimicrobial efficacy of 150 disk-shaped specimens with a diameter of 15 mm × 2 mm of unmodified (<i>n</i> = 15) and modified (<i>n</i> = 135) 3D-printed denture resin specimens after the addition of silanated ZrO<sub>2</sub>NPs, AgNPs, or TiO<sub>2</sub>NPs (<i>n</i> = 45) in varying concentrations (<i>n</i> = 15) of 0.5%, 1%, and 1.5% were compared using three oral bacteria (<i>S.pyogenes</i>, <i>S. aureus</i>, and <i>C. albicans</i>) as test subjects. Antimicrobial activity was tested by disk diffusion methods.</p><p><strong>Results: </strong>According to the results, when the three tested NPs (ZrO<sub>2</sub>NPs, AgNPs, and TiO<sub>2</sub>NPs) were added, the bacterial count significantly decreased compared with the unmodified 3D-printed resin. Additionally, the findings showed that as the concentration of the studied NPs increased, so did their antibacterial activity. At 1.5% and 1% concentrations, the AgNPs' antibacterial activity was negligible. However, the <i>in vitro</i> study's findings showed that, in terms of the kinds of microorganisms studied, there were no appreciable variations between the three tested NPs.</p><p><strong>Conclusion: </strong>The inclusion of ZrO<sub>2</sub>NPs, AgNPs, and TiO<sub>2</sub>NPs significantly had antimicrobial action against (<i>S. pyogenes</i>, <i>S. aureus</i>, and <i>C. albicans</i>).</p>","PeriodicalId":47247,"journal":{"name":"Journal of International Society of Preventive and Community Dentistry","volume":"15 1","pages":"42-49"},"PeriodicalIF":1.4000,"publicationDate":"2025-02-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11940513/pdf/","citationCount":"0","resultStr":"{\"title\":\"Antimicrobial Effect of Three Different Nanoparticles-Modified 3D-Printed Denture Resin: An <i>In Vitro</i> Study.\",\"authors\":\"Islam Basuny Abd Elhamid Abo Salh, Emad Boriqaa Add El-Salam, Amgad A Ezzat, Mohamed Aboshama, Ahmed Fathey Elhagali\",\"doi\":\"10.4103/jispcd.jispcd_53_24\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Aim: </strong>This study aimed to determine the antibacterial effectiveness of adding zirconia nanoparticles (NPs; ZrO<sub>2</sub>NPs), silver NPs (AgNPs), and titanium dioxide NPs (TiO<sub>2</sub>NPs) in various concentrations to three-dimensional (3D)-printed denture resin against <i>Candida Albicans</i>, <i>Streptococcus pyogenes</i>, and <i>Staphylococcus aureus</i>, this study was carried out.</p><p><strong>Materials and methods: </strong>The antimicrobial efficacy of 150 disk-shaped specimens with a diameter of 15 mm × 2 mm of unmodified (<i>n</i> = 15) and modified (<i>n</i> = 135) 3D-printed denture resin specimens after the addition of silanated ZrO<sub>2</sub>NPs, AgNPs, or TiO<sub>2</sub>NPs (<i>n</i> = 45) in varying concentrations (<i>n</i> = 15) of 0.5%, 1%, and 1.5% were compared using three oral bacteria (<i>S.pyogenes</i>, <i>S. aureus</i>, and <i>C. albicans</i>) as test subjects. Antimicrobial activity was tested by disk diffusion methods.</p><p><strong>Results: </strong>According to the results, when the three tested NPs (ZrO<sub>2</sub>NPs, AgNPs, and TiO<sub>2</sub>NPs) were added, the bacterial count significantly decreased compared with the unmodified 3D-printed resin. Additionally, the findings showed that as the concentration of the studied NPs increased, so did their antibacterial activity. At 1.5% and 1% concentrations, the AgNPs' antibacterial activity was negligible. However, the <i>in vitro</i> study's findings showed that, in terms of the kinds of microorganisms studied, there were no appreciable variations between the three tested NPs.</p><p><strong>Conclusion: </strong>The inclusion of ZrO<sub>2</sub>NPs, AgNPs, and TiO<sub>2</sub>NPs significantly had antimicrobial action against (<i>S. pyogenes</i>, <i>S. aureus</i>, and <i>C. albicans</i>).</p>\",\"PeriodicalId\":47247,\"journal\":{\"name\":\"Journal of International Society of Preventive and Community Dentistry\",\"volume\":\"15 1\",\"pages\":\"42-49\"},\"PeriodicalIF\":1.4000,\"publicationDate\":\"2025-02-26\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11940513/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of International Society of Preventive and Community Dentistry\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.4103/jispcd.jispcd_53_24\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2025/1/1 0:00:00\",\"PubModel\":\"eCollection\",\"JCR\":\"Q3\",\"JCRName\":\"DENTISTRY, ORAL SURGERY & MEDICINE\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of International Society of Preventive and Community Dentistry","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.4103/jispcd.jispcd_53_24","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/1/1 0:00:00","PubModel":"eCollection","JCR":"Q3","JCRName":"DENTISTRY, ORAL SURGERY & MEDICINE","Score":null,"Total":0}
Antimicrobial Effect of Three Different Nanoparticles-Modified 3D-Printed Denture Resin: An In Vitro Study.
Aim: This study aimed to determine the antibacterial effectiveness of adding zirconia nanoparticles (NPs; ZrO2NPs), silver NPs (AgNPs), and titanium dioxide NPs (TiO2NPs) in various concentrations to three-dimensional (3D)-printed denture resin against Candida Albicans, Streptococcus pyogenes, and Staphylococcus aureus, this study was carried out.
Materials and methods: The antimicrobial efficacy of 150 disk-shaped specimens with a diameter of 15 mm × 2 mm of unmodified (n = 15) and modified (n = 135) 3D-printed denture resin specimens after the addition of silanated ZrO2NPs, AgNPs, or TiO2NPs (n = 45) in varying concentrations (n = 15) of 0.5%, 1%, and 1.5% were compared using three oral bacteria (S.pyogenes, S. aureus, and C. albicans) as test subjects. Antimicrobial activity was tested by disk diffusion methods.
Results: According to the results, when the three tested NPs (ZrO2NPs, AgNPs, and TiO2NPs) were added, the bacterial count significantly decreased compared with the unmodified 3D-printed resin. Additionally, the findings showed that as the concentration of the studied NPs increased, so did their antibacterial activity. At 1.5% and 1% concentrations, the AgNPs' antibacterial activity was negligible. However, the in vitro study's findings showed that, in terms of the kinds of microorganisms studied, there were no appreciable variations between the three tested NPs.
Conclusion: The inclusion of ZrO2NPs, AgNPs, and TiO2NPs significantly had antimicrobial action against (S. pyogenes, S. aureus, and C. albicans).
期刊介绍：
It is a journal aimed for research, scientific facts and details covering all specialties of dentistry with a good determination for exploring and sharing the knowledge in the medical and dental fraternity. The scope is therefore huge covering almost all streams of dentistry - starting from original studies, systematic reviews, narrative reviews, very unique case reports. Journal scope is not limited to these subjects and is more wider covering all specialities of dentistry follows: -Preventive and Community dentistry (Dental public health)- Endodontics- Oral and maxillofacial pathology- Oral and maxillofacial radiology- Oral and maxillofacial surgery (also called oral surgery)- Orthodontics and dentofacial orthopedics- Periodontology (also called periodontics)- Pediatric dentistry (also called pedodontics)- Prosthodontics (also called prosthetic dentistry)- Oral medicine- Special needs dentistry (also called special care dentistry)- Oral Biology- Forensic odontology- Geriatric dentistry or Geriodontics- Preventive and Social Medicine (Public health)- Our journal appreciates research articles pertaining with advancement of dentistry, preventive and community dentistry including oral epidemiology, oral health services research, oral health education and promotion, behavioral sciences related to dentistry, dental jurisprudence, ethics and oral health, economics, and quality assessment, recent advances in preventive dentistry and community dentistry.
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