Simon Schalla, Joachim E Wildberger, Mitch J F G Ramaekers, Casper Mihl, Michael C McDermott, Lion Stammen, Kevin Vernooy, Thomas G Flohr
{"title":"光子计数检测器计算机断层成像心血管植入式电子设备引线。","authors":"Simon Schalla, Joachim E Wildberger, Mitch J F G Ramaekers, Casper Mihl, Michael C McDermott, Lion Stammen, Kevin Vernooy, Thomas G Flohr","doi":"10.1097/RLI.0000000000001177","DOIUrl":null,"url":null,"abstract":"<p><strong>Objectives: </strong>Computed tomography (CT) imaging of cardiovascular implantable electronic device (CIED) leads is currently hampered by large metal artifacts. Recently, photon-counting detector CT (PCD-CT) has been clinically introduced, offering high-resolution imaging with thin slice thicknesses and improved contrast-to-noise ratios. Suspected complications of CIED such as perforation, infection and venous obstruction could potentially be imaged with PCD-CT if metal artifacts were effectively reduced through adapted scan protocols and iterative metal artifact reduction algorithms (IMAR). The study evaluated the impact of various scan and reconstruction parameters, including different IMAR settings, on CIED lead visualization with PCD-CT in order to develop an optimized scan and reconstruction protocol for imaging leads.</p><p><strong>Materials and methods: </strong>Five different CIED leads were evaluated in a nonbeating heart phantom using a dual-source PCD-CT with electrocardiography-gated spectral standard resolution (collimation 144 × 0.4 mm) and nonspectral ultra-high resolution (UHR) mode (collimation 120 × 0.2 mm) spiral data acquisition. One scan was performed for each lead and each acquisition mode. Images were reconstructed with different slice thicknesses (0.2 mm, 0.4 mm, 0.6 mm), convolution kernels (Bv40, Bv44, Bv48, and Bv56), virtual monoenergetic energy levels (60-140 keV in steps of 10 keV), without and with different IMAR settings. The extent of metal artifacts was objectively evaluated using 4 different parameters. Additionally, 3 observers subjectively assessed image quality using a 5-point scale.</p><p><strong>Results: </strong>Metal artifacts increased with sharper kernels and higher keV levels in virtual monoenergetic reconstructions. The artifacts were not dependent on slice thickness. No significant differences in metal artifacts were observed between UHR and standard-resolution scans when using similar reconstruction parameters. IMAR effectively reduced artifacts across all kernels, slice thicknesses, and keV levels, with the \"neuro coils\" setting showing the best performance. Subjective analysis of image quality revealed that thinnest slices and sharpest kernels (0.2 mm, Bv56) allowed for better delineation of fine structures, such as the shape of helices, while reconstructions with thicker slices and softer kernels (0.6 mm, Bv40) were preferred for visualizing general lead appearance and adjacent anatomical structures.</p><p><strong>Conclusions: </strong>Ultra-high and standard resolution PCD-CT with IMAR enables good-quality imaging of CIED leads, showing even small details without compromising the visibility of nearby structures. A dedicated acquisition and reconstruction protocol comprising an UHR scan with 2 reconstructions (0.2 mm/Bv56 and 0.6 mm/Bv40, using IMAR) appears optimal for PCD-CT imaging of CIED leads.</p>","PeriodicalId":14486,"journal":{"name":"Investigative Radiology","volume":" ","pages":""},"PeriodicalIF":7.0000,"publicationDate":"2025-03-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Imaging of Cardiovascular Implantable Electronic Device Leads With Photon-Counting Detector Computed Tomography.\",\"authors\":\"Simon Schalla, Joachim E Wildberger, Mitch J F G Ramaekers, Casper Mihl, Michael C McDermott, Lion Stammen, Kevin Vernooy, Thomas G Flohr\",\"doi\":\"10.1097/RLI.0000000000001177\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Objectives: </strong>Computed tomography (CT) imaging of cardiovascular implantable electronic device (CIED) leads is currently hampered by large metal artifacts. Recently, photon-counting detector CT (PCD-CT) has been clinically introduced, offering high-resolution imaging with thin slice thicknesses and improved contrast-to-noise ratios. Suspected complications of CIED such as perforation, infection and venous obstruction could potentially be imaged with PCD-CT if metal artifacts were effectively reduced through adapted scan protocols and iterative metal artifact reduction algorithms (IMAR). The study evaluated the impact of various scan and reconstruction parameters, including different IMAR settings, on CIED lead visualization with PCD-CT in order to develop an optimized scan and reconstruction protocol for imaging leads.</p><p><strong>Materials and methods: </strong>Five different CIED leads were evaluated in a nonbeating heart phantom using a dual-source PCD-CT with electrocardiography-gated spectral standard resolution (collimation 144 × 0.4 mm) and nonspectral ultra-high resolution (UHR) mode (collimation 120 × 0.2 mm) spiral data acquisition. One scan was performed for each lead and each acquisition mode. Images were reconstructed with different slice thicknesses (0.2 mm, 0.4 mm, 0.6 mm), convolution kernels (Bv40, Bv44, Bv48, and Bv56), virtual monoenergetic energy levels (60-140 keV in steps of 10 keV), without and with different IMAR settings. The extent of metal artifacts was objectively evaluated using 4 different parameters. Additionally, 3 observers subjectively assessed image quality using a 5-point scale.</p><p><strong>Results: </strong>Metal artifacts increased with sharper kernels and higher keV levels in virtual monoenergetic reconstructions. The artifacts were not dependent on slice thickness. No significant differences in metal artifacts were observed between UHR and standard-resolution scans when using similar reconstruction parameters. IMAR effectively reduced artifacts across all kernels, slice thicknesses, and keV levels, with the \\\"neuro coils\\\" setting showing the best performance. Subjective analysis of image quality revealed that thinnest slices and sharpest kernels (0.2 mm, Bv56) allowed for better delineation of fine structures, such as the shape of helices, while reconstructions with thicker slices and softer kernels (0.6 mm, Bv40) were preferred for visualizing general lead appearance and adjacent anatomical structures.</p><p><strong>Conclusions: </strong>Ultra-high and standard resolution PCD-CT with IMAR enables good-quality imaging of CIED leads, showing even small details without compromising the visibility of nearby structures. A dedicated acquisition and reconstruction protocol comprising an UHR scan with 2 reconstructions (0.2 mm/Bv56 and 0.6 mm/Bv40, using IMAR) appears optimal for PCD-CT imaging of CIED leads.</p>\",\"PeriodicalId\":14486,\"journal\":{\"name\":\"Investigative Radiology\",\"volume\":\" \",\"pages\":\"\"},\"PeriodicalIF\":7.0000,\"publicationDate\":\"2025-03-26\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Investigative Radiology\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1097/RLI.0000000000001177\",\"RegionNum\":1,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Investigative Radiology","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1097/RLI.0000000000001177","RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING","Score":null,"Total":0}
引用次数: 0
摘要
目的:心血管植入式电子设备(CIED)引线的计算机断层扫描(CT)成像目前受到大型金属伪影的阻碍。最近,光子计数检测器CT (PCD-CT)已被临床引入,提供高分辨率成像,薄层厚度和提高的噪比。如果通过合适的扫描方案和迭代金属伪影减少算法(IMAR)有效地减少金属伪影,则可能用PCD-CT成像CIED的疑似并发症,如穿孔、感染和静脉阻塞。该研究评估了各种扫描和重建参数(包括不同的IMAR设置)对PCD-CT CIED导联可视化的影响,以制定优化的导联成像扫描和重建方案。材料和方法:采用双源PCD-CT,采用心电图门控光谱标准分辨率(准直144 × 0.4 mm)和非光谱超高分辨率(UHR)模式(准直120 × 0.2 mm)螺旋数据采集,在非跳动心脏影中评估5种不同的CIED导联。每个导联和每个采集模式进行一次扫描。采用不同的切片厚度(0.2 mm, 0.4 mm, 0.6 mm),卷积核(Bv40, Bv44, Bv48和Bv56),虚拟单能能级(60-140 keV,每10 keV),无IMAR设置和不同IMAR设置重建图像。采用4种不同参数客观评价金属伪影的程度。此外,3名观察员使用5分制主观评估图像质量。结果:在虚拟单能重建中,金属伪影增加,核粒更清晰,keV水平更高。伪影不依赖于薄片厚度。当使用相似的重建参数时,在UHR和标准分辨率扫描之间观察到金属伪影没有显着差异。IMAR有效地减少了所有内核、切片厚度和keV水平上的伪影,其中“神经线圈”设置表现出最佳性能。图像质量的主观分析表明,最薄的切片和最锋利的核(0.2 mm, Bv56)可以更好地描绘精细结构,如螺旋形状,而更厚的切片和更软的核(0.6 mm, Bv40)的重建更适合于可视化一般的铅外观和邻近的解剖结构。结论:带IMAR的超高分辨率和标准分辨率的PCD-CT可以实现高质量的CIED导联成像,即使是很小的细节也能显示出来,而不会影响附近结构的可见性。专用采集和重建方案包括UHR扫描和2次重建(0.2 mm/Bv56和0.6 mm/Bv40,使用IMAR),对于CIED导联的PCD-CT成像是最佳的。
Imaging of Cardiovascular Implantable Electronic Device Leads With Photon-Counting Detector Computed Tomography.
Objectives: Computed tomography (CT) imaging of cardiovascular implantable electronic device (CIED) leads is currently hampered by large metal artifacts. Recently, photon-counting detector CT (PCD-CT) has been clinically introduced, offering high-resolution imaging with thin slice thicknesses and improved contrast-to-noise ratios. Suspected complications of CIED such as perforation, infection and venous obstruction could potentially be imaged with PCD-CT if metal artifacts were effectively reduced through adapted scan protocols and iterative metal artifact reduction algorithms (IMAR). The study evaluated the impact of various scan and reconstruction parameters, including different IMAR settings, on CIED lead visualization with PCD-CT in order to develop an optimized scan and reconstruction protocol for imaging leads.
Materials and methods: Five different CIED leads were evaluated in a nonbeating heart phantom using a dual-source PCD-CT with electrocardiography-gated spectral standard resolution (collimation 144 × 0.4 mm) and nonspectral ultra-high resolution (UHR) mode (collimation 120 × 0.2 mm) spiral data acquisition. One scan was performed for each lead and each acquisition mode. Images were reconstructed with different slice thicknesses (0.2 mm, 0.4 mm, 0.6 mm), convolution kernels (Bv40, Bv44, Bv48, and Bv56), virtual monoenergetic energy levels (60-140 keV in steps of 10 keV), without and with different IMAR settings. The extent of metal artifacts was objectively evaluated using 4 different parameters. Additionally, 3 observers subjectively assessed image quality using a 5-point scale.
Results: Metal artifacts increased with sharper kernels and higher keV levels in virtual monoenergetic reconstructions. The artifacts were not dependent on slice thickness. No significant differences in metal artifacts were observed between UHR and standard-resolution scans when using similar reconstruction parameters. IMAR effectively reduced artifacts across all kernels, slice thicknesses, and keV levels, with the "neuro coils" setting showing the best performance. Subjective analysis of image quality revealed that thinnest slices and sharpest kernels (0.2 mm, Bv56) allowed for better delineation of fine structures, such as the shape of helices, while reconstructions with thicker slices and softer kernels (0.6 mm, Bv40) were preferred for visualizing general lead appearance and adjacent anatomical structures.
Conclusions: Ultra-high and standard resolution PCD-CT with IMAR enables good-quality imaging of CIED leads, showing even small details without compromising the visibility of nearby structures. A dedicated acquisition and reconstruction protocol comprising an UHR scan with 2 reconstructions (0.2 mm/Bv56 and 0.6 mm/Bv40, using IMAR) appears optimal for PCD-CT imaging of CIED leads.
期刊介绍:
Investigative Radiology publishes original, peer-reviewed reports on clinical and laboratory investigations in diagnostic imaging, the diagnostic use of radioactive isotopes, computed tomography, positron emission tomography, magnetic resonance imaging, ultrasound, digital subtraction angiography, and related modalities. Emphasis is on early and timely publication. Primarily research-oriented, the journal also includes a wide variety of features of interest to clinical radiologists.