Raelene M Cowie, Jens Schwiesau, Thomas M Grupp, Adam Briscoe, Louise M Jennings
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Third Body Wear of an All-Polymer, PEEK-OPTIMA™ on Ultra-High-Molecular-Weight Polyethylene Total Knee Replacement.
Experimental wear simulation of a PEEK-OPTIMA™ polymer-on-UHMWPE total knee replacement has shown equivalent UHMWPE wear to conventional knee replacement materials (cobalt chrome-on-UHMWPE) when tested in a clean environment. The aim of this study was to experimentally investigate the wear of this all-polymer total knee replacement under third body wear conditions. Three PEEK-OPTIMA™ and three cobalt chrome femoral components articulating against all-polyethylene tibial components were tested in a knee simulator. One million cycles of wear simulation was carried out in clean lubricant under conditions replicating walking followed by one million cycles with the lubricant contaminated with porcine bone particles, then one million cycles with PMMA cement particles. UHMWPE wear was determined gravimetrically. Statistical analysis compared UHMWPE wear against PEEK femoral components to cobalt chrome. In clean lubricant and with bone particles in the lubricant, there was no significant difference (p > 0.05) in UHMWPE wear against the different femoral component materials, and wear rates were similar under both conditions. With PMMA particles, there was a dramatic increase in UHMWPE wear for both knee replacement systems but no significant difference (p > 0.05) in UHMWPE wear between the femoral component materials. This is the first study to investigate wear of an all-polymer knee under third body wear conditions.
期刊介绍:
Aims
Bioengineering (ISSN 2306-5354) provides an advanced forum for the science and technology of bioengineering. It publishes original research papers, comprehensive reviews, communications and case reports. Our aim is to encourage scientists to publish their experimental and theoretical results in as much detail as possible. All aspects of bioengineering are welcomed from theoretical concepts to education and applications. There is no restriction on the length of the papers. The full experimental details must be provided so that the results can be reproduced. There are, in addition, four key features of this Journal:
● We are introducing a new concept in scientific and technical publications “The Translational Case Report in Bioengineering”. It is a descriptive explanatory analysis of a transformative or translational event. Understanding that the goal of bioengineering scholarship is to advance towards a transformative or clinical solution to an identified transformative/clinical need, the translational case report is used to explore causation in order to find underlying principles that may guide other similar transformative/translational undertakings.
● Manuscripts regarding research proposals and research ideas will be particularly welcomed.
● Electronic files and software regarding the full details of the calculation and experimental procedure, if unable to be published in a normal way, can be deposited as supplementary material.
● We also accept manuscripts communicating to a broader audience with regard to research projects financed with public funds.
Scope
● Bionics and biological cybernetics: implantology; bio–abio interfaces
● Bioelectronics: wearable electronics; implantable electronics; “more than Moore” electronics; bioelectronics devices
● Bioprocess and biosystems engineering and applications: bioprocess design; biocatalysis; bioseparation and bioreactors; bioinformatics; bioenergy; etc.
● Biomolecular, cellular and tissue engineering and applications: tissue engineering; chromosome engineering; embryo engineering; cellular, molecular and synthetic biology; metabolic engineering; bio-nanotechnology; micro/nano technologies; genetic engineering; transgenic technology
● Biomedical engineering and applications: biomechatronics; biomedical electronics; biomechanics; biomaterials; biomimetics; biomedical diagnostics; biomedical therapy; biomedical devices; sensors and circuits; biomedical imaging and medical information systems; implants and regenerative medicine; neurotechnology; clinical engineering; rehabilitation engineering
● Biochemical engineering and applications: metabolic pathway engineering; modeling and simulation
● Translational bioengineering