超高分子量聚乙烯全聚合物PEEK-OPTIMA™全膝关节置换术的第三体磨损。

IF 3.8 3区 医学 Q2 ENGINEERING, BIOMEDICAL
Raelene M Cowie, Jens Schwiesau, Thomas M Grupp, Adam Briscoe, Louise M Jennings
{"title":"超高分子量聚乙烯全聚合物PEEK-OPTIMA™全膝关节置换术的第三体磨损。","authors":"Raelene M Cowie, Jens Schwiesau, Thomas M Grupp, Adam Briscoe, Louise M Jennings","doi":"10.3390/bioengineering12030261","DOIUrl":null,"url":null,"abstract":"<p><p>Experimental wear simulation of a PEEK-OPTIMA™ polymer-on-UHMWPE total knee replacement has shown equivalent UHMWPE wear to conventional knee replacement materials (cobalt chrome-on-UHMWPE) when tested in a clean environment. The aim of this study was to experimentally investigate the wear of this all-polymer total knee replacement under third body wear conditions. Three PEEK-OPTIMA™ and three cobalt chrome femoral components articulating against all-polyethylene tibial components were tested in a knee simulator. One million cycles of wear simulation was carried out in clean lubricant under conditions replicating walking followed by one million cycles with the lubricant contaminated with porcine bone particles, then one million cycles with PMMA cement particles. UHMWPE wear was determined gravimetrically. Statistical analysis compared UHMWPE wear against PEEK femoral components to cobalt chrome. In clean lubricant and with bone particles in the lubricant, there was no significant difference (<i>p</i> > 0.05) in UHMWPE wear against the different femoral component materials, and wear rates were similar under both conditions. With PMMA particles, there was a dramatic increase in UHMWPE wear for both knee replacement systems but no significant difference (<i>p</i> > 0.05) in UHMWPE wear between the femoral component materials. This is the first study to investigate wear of an all-polymer knee under third body wear conditions.</p>","PeriodicalId":8874,"journal":{"name":"Bioengineering","volume":"12 3","pages":""},"PeriodicalIF":3.8000,"publicationDate":"2025-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11939626/pdf/","citationCount":"0","resultStr":"{\"title\":\"Third Body Wear of an All-Polymer, PEEK-OPTIMA™ on Ultra-High-Molecular-Weight Polyethylene Total Knee Replacement.\",\"authors\":\"Raelene M Cowie, Jens Schwiesau, Thomas M Grupp, Adam Briscoe, Louise M Jennings\",\"doi\":\"10.3390/bioengineering12030261\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Experimental wear simulation of a PEEK-OPTIMA™ polymer-on-UHMWPE total knee replacement has shown equivalent UHMWPE wear to conventional knee replacement materials (cobalt chrome-on-UHMWPE) when tested in a clean environment. The aim of this study was to experimentally investigate the wear of this all-polymer total knee replacement under third body wear conditions. Three PEEK-OPTIMA™ and three cobalt chrome femoral components articulating against all-polyethylene tibial components were tested in a knee simulator. One million cycles of wear simulation was carried out in clean lubricant under conditions replicating walking followed by one million cycles with the lubricant contaminated with porcine bone particles, then one million cycles with PMMA cement particles. UHMWPE wear was determined gravimetrically. Statistical analysis compared UHMWPE wear against PEEK femoral components to cobalt chrome. In clean lubricant and with bone particles in the lubricant, there was no significant difference (<i>p</i> > 0.05) in UHMWPE wear against the different femoral component materials, and wear rates were similar under both conditions. With PMMA particles, there was a dramatic increase in UHMWPE wear for both knee replacement systems but no significant difference (<i>p</i> > 0.05) in UHMWPE wear between the femoral component materials. This is the first study to investigate wear of an all-polymer knee under third body wear conditions.</p>\",\"PeriodicalId\":8874,\"journal\":{\"name\":\"Bioengineering\",\"volume\":\"12 3\",\"pages\":\"\"},\"PeriodicalIF\":3.8000,\"publicationDate\":\"2025-03-05\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11939626/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Bioengineering\",\"FirstCategoryId\":\"5\",\"ListUrlMain\":\"https://doi.org/10.3390/bioengineering12030261\",\"RegionNum\":3,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"ENGINEERING, BIOMEDICAL\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Bioengineering","FirstCategoryId":"5","ListUrlMain":"https://doi.org/10.3390/bioengineering12030261","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"ENGINEERING, BIOMEDICAL","Score":null,"Total":0}
引用次数: 0

摘要

PEEK-OPTIMA™聚合物-UHMWPE全膝关节置换术的实验磨损模拟显示,在清洁环境中测试时,UHMWPE与传统膝关节置换术材料(钴铬-UHMWPE)的磨损相当。本研究的目的是实验研究这种全聚合物全膝关节置换术在第三体磨损条件下的磨损情况。在膝关节模拟器中测试了三个PEEK-OPTIMA™和三个钴铬股骨组件与全聚乙烯胫骨组件的接合。在模拟行走的清洁润滑条件下进行了100万次磨损模拟,然后在污染猪骨颗粒的润滑条件下进行了100万次磨损模拟,然后在污染PMMA水泥颗粒的润滑条件下进行了100万次磨损模拟。用重量法测定了超高分子量聚乙烯的磨损情况。统计分析比较了UHMWPE与PEEK股骨部件和钴铬的磨损。在清洁润滑剂和含有骨颗粒的润滑剂中,不同股骨假体材料的UHMWPE磨损无显著差异(p > 0.05),两种情况下的磨损率相似。使用PMMA颗粒,两种膝关节置换系统的UHMWPE磨损显著增加,但股骨假体材料之间的UHMWPE磨损无显著差异(p > 0.05)。这是第一个在第三体磨损条件下调查全聚合物膝关节磨损的研究。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Third Body Wear of an All-Polymer, PEEK-OPTIMA™ on Ultra-High-Molecular-Weight Polyethylene Total Knee Replacement.

Experimental wear simulation of a PEEK-OPTIMA™ polymer-on-UHMWPE total knee replacement has shown equivalent UHMWPE wear to conventional knee replacement materials (cobalt chrome-on-UHMWPE) when tested in a clean environment. The aim of this study was to experimentally investigate the wear of this all-polymer total knee replacement under third body wear conditions. Three PEEK-OPTIMA™ and three cobalt chrome femoral components articulating against all-polyethylene tibial components were tested in a knee simulator. One million cycles of wear simulation was carried out in clean lubricant under conditions replicating walking followed by one million cycles with the lubricant contaminated with porcine bone particles, then one million cycles with PMMA cement particles. UHMWPE wear was determined gravimetrically. Statistical analysis compared UHMWPE wear against PEEK femoral components to cobalt chrome. In clean lubricant and with bone particles in the lubricant, there was no significant difference (p > 0.05) in UHMWPE wear against the different femoral component materials, and wear rates were similar under both conditions. With PMMA particles, there was a dramatic increase in UHMWPE wear for both knee replacement systems but no significant difference (p > 0.05) in UHMWPE wear between the femoral component materials. This is the first study to investigate wear of an all-polymer knee under third body wear conditions.

求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
Bioengineering
Bioengineering Chemical Engineering-Bioengineering
CiteScore
4.00
自引率
8.70%
发文量
661
期刊介绍: Aims Bioengineering (ISSN 2306-5354) provides an advanced forum for the science and technology of bioengineering. It publishes original research papers, comprehensive reviews, communications and case reports. Our aim is to encourage scientists to publish their experimental and theoretical results in as much detail as possible. All aspects of bioengineering are welcomed from theoretical concepts to education and applications. There is no restriction on the length of the papers. The full experimental details must be provided so that the results can be reproduced. There are, in addition, four key features of this Journal: ● We are introducing a new concept in scientific and technical publications “The Translational Case Report in Bioengineering”. It is a descriptive explanatory analysis of a transformative or translational event. Understanding that the goal of bioengineering scholarship is to advance towards a transformative or clinical solution to an identified transformative/clinical need, the translational case report is used to explore causation in order to find underlying principles that may guide other similar transformative/translational undertakings. ● Manuscripts regarding research proposals and research ideas will be particularly welcomed. ● Electronic files and software regarding the full details of the calculation and experimental procedure, if unable to be published in a normal way, can be deposited as supplementary material. ● We also accept manuscripts communicating to a broader audience with regard to research projects financed with public funds. Scope ● Bionics and biological cybernetics: implantology; bio–abio interfaces ● Bioelectronics: wearable electronics; implantable electronics; “more than Moore” electronics; bioelectronics devices ● Bioprocess and biosystems engineering and applications: bioprocess design; biocatalysis; bioseparation and bioreactors; bioinformatics; bioenergy; etc. ● Biomolecular, cellular and tissue engineering and applications: tissue engineering; chromosome engineering; embryo engineering; cellular, molecular and synthetic biology; metabolic engineering; bio-nanotechnology; micro/nano technologies; genetic engineering; transgenic technology ● Biomedical engineering and applications: biomechatronics; biomedical electronics; biomechanics; biomaterials; biomimetics; biomedical diagnostics; biomedical therapy; biomedical devices; sensors and circuits; biomedical imaging and medical information systems; implants and regenerative medicine; neurotechnology; clinical engineering; rehabilitation engineering ● Biochemical engineering and applications: metabolic pathway engineering; modeling and simulation ● Translational bioengineering
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信