{"title":"Development and Validation of a Hypertension Risk Prediction Model Based on Particle Swarm Optimization-Support Vector Machine.","authors":"Rou You, Qiaoli Tao, Siqi Wang, Lixing Cao, Kexue Zeng, Juncai Lin, Hao Chen","doi":"10.3390/bioengineering12030238","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>Hypertension is a prevalent health issue, especially among the elderly, and is linked to multiple complications. Early and accurate detection is crucial for effective management. Traditional detection methods may be limited in accuracy and efficiency, prompting the exploration of advanced computational techniques. Machine learning algorithms, combined with optimization methods, show potential in enhancing hypertension detection.</p><p><strong>Methods: </strong>In 2022, data from 1460 hypertensive and 1416 non-hypertensive individuals aged 65 and above were collected from the Lujingdong Outpatient Department of the Guangdong Second Traditional Chinese Medicine Hospital. Support Vector Machine (SVM) and Particle Swarm Optimization-Support Vector Machine (PSO-SVM) models were developed, validated using the holdout method, and evaluated based on sensitivity, specificity, positive predictive value (PPV), accuracy, G-mean, F1 score, Matthews correlation coefficient (MCC), and the area under the curve (AUC) of the receiver operating characteristic curve (ROC curve).</p><p><strong>Results: </strong>The PSO-SVM model outperformed the standard SVM, especially in sensitivity (93.9%), F1 score (0.838), and AUC-ROC (0.871).</p><p><strong>Conclusion: </strong>The PSO-SVM model is effective for complex classifications, particularly in hypertension detection, providing a basis for early diagnosis and treatment.</p>","PeriodicalId":8874,"journal":{"name":"Bioengineering","volume":"12 3","pages":""},"PeriodicalIF":3.8000,"publicationDate":"2025-02-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11939598/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Bioengineering","FirstCategoryId":"5","ListUrlMain":"https://doi.org/10.3390/bioengineering12030238","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"ENGINEERING, BIOMEDICAL","Score":null,"Total":0}
Development and Validation of a Hypertension Risk Prediction Model Based on Particle Swarm Optimization-Support Vector Machine.
Background: Hypertension is a prevalent health issue, especially among the elderly, and is linked to multiple complications. Early and accurate detection is crucial for effective management. Traditional detection methods may be limited in accuracy and efficiency, prompting the exploration of advanced computational techniques. Machine learning algorithms, combined with optimization methods, show potential in enhancing hypertension detection.
Methods: In 2022, data from 1460 hypertensive and 1416 non-hypertensive individuals aged 65 and above were collected from the Lujingdong Outpatient Department of the Guangdong Second Traditional Chinese Medicine Hospital. Support Vector Machine (SVM) and Particle Swarm Optimization-Support Vector Machine (PSO-SVM) models were developed, validated using the holdout method, and evaluated based on sensitivity, specificity, positive predictive value (PPV), accuracy, G-mean, F1 score, Matthews correlation coefficient (MCC), and the area under the curve (AUC) of the receiver operating characteristic curve (ROC curve).
Results: The PSO-SVM model outperformed the standard SVM, especially in sensitivity (93.9%), F1 score (0.838), and AUC-ROC (0.871).
Conclusion: The PSO-SVM model is effective for complex classifications, particularly in hypertension detection, providing a basis for early diagnosis and treatment.
期刊介绍:
Aims
Bioengineering (ISSN 2306-5354) provides an advanced forum for the science and technology of bioengineering. It publishes original research papers, comprehensive reviews, communications and case reports. Our aim is to encourage scientists to publish their experimental and theoretical results in as much detail as possible. All aspects of bioengineering are welcomed from theoretical concepts to education and applications. There is no restriction on the length of the papers. The full experimental details must be provided so that the results can be reproduced. There are, in addition, four key features of this Journal:
● We are introducing a new concept in scientific and technical publications “The Translational Case Report in Bioengineering”. It is a descriptive explanatory analysis of a transformative or translational event. Understanding that the goal of bioengineering scholarship is to advance towards a transformative or clinical solution to an identified transformative/clinical need, the translational case report is used to explore causation in order to find underlying principles that may guide other similar transformative/translational undertakings.
● Manuscripts regarding research proposals and research ideas will be particularly welcomed.
● Electronic files and software regarding the full details of the calculation and experimental procedure, if unable to be published in a normal way, can be deposited as supplementary material.
● We also accept manuscripts communicating to a broader audience with regard to research projects financed with public funds.
Scope
● Bionics and biological cybernetics: implantology; bio–abio interfaces
● Bioelectronics: wearable electronics; implantable electronics; “more than Moore” electronics; bioelectronics devices
● Bioprocess and biosystems engineering and applications: bioprocess design; biocatalysis; bioseparation and bioreactors; bioinformatics; bioenergy; etc.
● Biomolecular, cellular and tissue engineering and applications: tissue engineering; chromosome engineering; embryo engineering; cellular, molecular and synthetic biology; metabolic engineering; bio-nanotechnology; micro/nano technologies; genetic engineering; transgenic technology
● Biomedical engineering and applications: biomechatronics; biomedical electronics; biomechanics; biomaterials; biomimetics; biomedical diagnostics; biomedical therapy; biomedical devices; sensors and circuits; biomedical imaging and medical information systems; implants and regenerative medicine; neurotechnology; clinical engineering; rehabilitation engineering
● Biochemical engineering and applications: metabolic pathway engineering; modeling and simulation
● Translational bioengineering