在Tc-99m MDP骨骼显像上对Erdheim-Chester病的刻板描述。

IF 0.8 4区医学 Q3 MEDICINE, GENERAL & INTERNAL

Journal of the Pakistan Medical Association Pub Date : 2025-03-01 DOI:10.47391/JPMA.25-23

Syeda Azam Najam, Xain Tauqeer, Aamna Hassan, Kashif Siddique

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引用次数: 0

摘要

Erdheim-Chester病（ECD）是一种罕见的全身性组织细胞疾病，其特征是对称的骨骼受累和可变的内脏表现。Tc-99m MDP骨显像、CT、MRI和FDG PET-CT对诊断和疾病作图至关重要。ECD的病程取决于骨外受累情况，并伴有包括心脏和肾功能衰竭在内的潜在并发症。我们提出的病例ECD与双侧腿痛和眼眶受累。影像学显示混合硬化和溶解性骨骼病变，小脑病变，眶内软组织肿块，纵隔和腹膜后浸润。

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Stereotypical depiction of Erdheim-Chester Disease on Tc-99m MDP skeletal scintigraphy.

Erdheim-Chester Disease (ECD) is a rare systemic histiocytic disorder characterized by symmetrical skeletal involvement and variable visceral manifestations. Tc-99m MDP bone scintigraphy, CT, MRI, and FDG PET-CT are essential for diagnosis and disease mapping. ECD's course depends on extraosseous involvement, with potential complications including heart and renal failure. We present the case of ECD with bilateral leg pain and orbital involvement. Imaging revealed mixed sclerotic and lytic skeletal lesions, cerebellar lesions, intraorbital soft tissue masses, mediastinal and retroperitoneal infiltration.

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来源期刊

Journal of the Pakistan Medical Association Medicine-General Medicine

CiteScore

1.10

自引率

11.10%

发文量

983

审稿时长

3-6 weeks

期刊介绍： Primarily being a medical journal, JPMA publishes scholarly research focusing on the various fields in the areas of health and medical education. It publishes original research describing recent advances in health particularly clinical studies, clinical trials, assessments of pathogens of diagnostic importance, medical genetics and epidemiological studies. Review articles highlighting importance of various issues in the domain of public health, drug research and medical education are also accepted. As a leading journal of South Asia, JPMA remains cognizant of the recent advances in the rapidly growing fields of biomedical sciences, it invites and encourages scholars to write short reviews and invited editorials on the emerging issues. We particularly aim to promote health standards of developing countries by encouraging manuscript submissions on issues affecting the public health and health delivery services.