Efficacy of Two Different Concentrations of Iodine-potassium Iodide Solution in Endodontic Retreatment: A Randomised Double-blinded Clinical Trial.

Objective: This study aimed to evaluate the antibacterial effectiveness of two concentrations of iodine-potassium iodide (IKI) used as the final irrigating solution during endodontic retreatment.

Methods: Thirty symptom-free root-filled anterior teeth with chronic apical periodontitis (<5*5mm) were included. They were divided into two groups consisting of 15 teeth according to the method of final irrigation. Group 1 were irrigated with 2% IKI, and Group 2 with 5% IKI. The direct bacterial viable count method was performed to determine the number of colony-forming units (CFUs) before and after disinfection. The reduction in bacterial count was assessed, and statistical analysis was performed using Mann-Whitney U tests with a 95% confidence level.

Results: Irrigation with 5% IKI resulted in significantly reduced bacterial counts than 2% IKI irrigation (p<0.05), indicating greater antibacterial effects.

Conclusion: The use of a 5% IKI solution as the final irrigating agent in endodontic retreatment cases with chronic apical periodontitis significantly reduces bacterial counts compared to a 2% IKI solution. The 5% IKI solution therefore exhibited a superior antibacterial effect. Consequently, 5% IKI solution application improves microbiological outcomes and enhances the overall disinfection of the root canal system. (EEJ-2024-08-131).