尽管存在不良事件风险，抗精神病药物的使用仍在持续增加

The Brown University Psychopharmacology Update Pub Date : 2025-03-27 DOI:10.1002/pu.31298

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引用次数: 0

摘要

一项系统回顾和荟萃分析发现，在过去的50年里，同时使用两种或两种以上抗精神病药物的人数持续增加，尽管它与不良事件的高风险相关。与单一抗精神病药物治疗相比，多种药物治疗与复发和精神病院住院等不良后果的高风险相关。该综述和荟萃分析的结果于2024年11月12日在线发表在《柳叶刀精神病学》上。

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Despite adverse event risk, anti psychotic polypharmacy has continued to rise

Concurrent use of two or more antipsychotics has continued to increase over the past 50 years despite its association with a higher risk of adverse events, a systematic review and meta-analysis has found. In comparison with antipsychotic monotherapy, polypharmacy was associated with higher risk of adverse outcomes such as relapse and psychiatric hospitalization. Results of the review and meta-analysis were published online Nov. 12, 2024, in Lancet Psychiatry.

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The Brown University Psychopharmacology Update

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