{"title":"青年人中疼痛性颞下颌紊乱和重叠性原发性头痛的患病率","authors":"Cristina Rocha Exposto, Mojdeh Mansoori, Bodil Hammer Bech, Lene Baad-Hansen","doi":"10.1002/ejp.70013","DOIUrl":null,"url":null,"abstract":"<div>\n \n \n <section>\n \n <h3> Background</h3>\n \n <p>Large population-based estimates of the prevalence of painful temporomandibular disorders (p-TMD) utilising standardised screening tools are scarce and have not investigated the prevalence of overlapping primary headaches. We aimed to estimate the prevalence of p-TMD in a large population of young adults (18 to 23 years) and to estimate the co-occurrence of p-TMD and two primary headaches, migraine and tension-type headache (TTH). The study also aimed to examine the extent of psychological (PHQ-4) and physical (PHQ-15) comorbidities and report prevalence across three gender categories (<i>women</i>, <i>men</i> and <i>other</i>).</p>\n </section>\n \n <section>\n \n <h3> Methods</h3>\n \n <p>Survey data from the Danish National Birth Cohort were collected (<i>n</i> = 11,982), in a cross-sectional observational design. A sensitivity analysis was conducted to address participation bias, revealing minimal impact on the estimates.</p>\n </section>\n \n <section>\n \n <h3> Results</h3>\n \n <p>The overall prevalence of p-TMD was 26.4% with gender-specific prevalence of <i>women:</i> 31.5%, <i>other:</i> 39.2% and <i>men:</i> 16.8%. Among those with p-TMD, 80.5% reported headaches at least once a month, and 13.8% over 15 days monthly. For the p-TMD individuals with a medical headache diagnosis, 31.9% experienced TTH and 10.9% migraine. The study also identified a higher proportion of moderate/severe psychological distress and physical symptoms in the p-TMD group compared to the non-p-TMD group. Logistic regression revealed a positive association between PHQ-4 and p-TMD, modified by gender (<i>p</i> = 0.016).</p>\n </section>\n \n <section>\n \n <h3> Conclusions</h3>\n \n <p>High overall prevalence of p-TMD and overlapping primary headaches was found in young adults. In addition, the study reports gender-specific associations between p-TMD, psychological distress and physical comorbidities indicating that this association is stronger for men than for women.</p>\n </section>\n \n <section>\n \n <h3> Significance Statement</h3>\n \n <p>This study found a higher-than-expected prevalence of painful temporomandibular disorders in young adults. It is based on a large population cohort and used standardised and validated screening tools. The study also reported common co-occurrence of primary headaches and explored gender differences. The study raises awareness for a possibly underestimated health burden in young individuals, particularly among individuals experiencing psychological distress and multiple physical symptoms.</p>\n </section>\n </div>","PeriodicalId":12021,"journal":{"name":"European Journal of Pain","volume":"29 5","pages":""},"PeriodicalIF":3.5000,"publicationDate":"2025-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/ejp.70013","citationCount":"0","resultStr":"{\"title\":\"Prevalence of Painful Temporomandibular Disorders and Overlapping Primary Headaches Among Young Adults\",\"authors\":\"Cristina Rocha Exposto, Mojdeh Mansoori, Bodil Hammer Bech, Lene Baad-Hansen\",\"doi\":\"10.1002/ejp.70013\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div>\\n \\n \\n <section>\\n \\n <h3> Background</h3>\\n \\n <p>Large population-based estimates of the prevalence of painful temporomandibular disorders (p-TMD) utilising standardised screening tools are scarce and have not investigated the prevalence of overlapping primary headaches. We aimed to estimate the prevalence of p-TMD in a large population of young adults (18 to 23 years) and to estimate the co-occurrence of p-TMD and two primary headaches, migraine and tension-type headache (TTH). The study also aimed to examine the extent of psychological (PHQ-4) and physical (PHQ-15) comorbidities and report prevalence across three gender categories (<i>women</i>, <i>men</i> and <i>other</i>).</p>\\n </section>\\n \\n <section>\\n \\n <h3> Methods</h3>\\n \\n <p>Survey data from the Danish National Birth Cohort were collected (<i>n</i> = 11,982), in a cross-sectional observational design. A sensitivity analysis was conducted to address participation bias, revealing minimal impact on the estimates.</p>\\n </section>\\n \\n <section>\\n \\n <h3> Results</h3>\\n \\n <p>The overall prevalence of p-TMD was 26.4% with gender-specific prevalence of <i>women:</i> 31.5%, <i>other:</i> 39.2% and <i>men:</i> 16.8%. Among those with p-TMD, 80.5% reported headaches at least once a month, and 13.8% over 15 days monthly. For the p-TMD individuals with a medical headache diagnosis, 31.9% experienced TTH and 10.9% migraine. The study also identified a higher proportion of moderate/severe psychological distress and physical symptoms in the p-TMD group compared to the non-p-TMD group. Logistic regression revealed a positive association between PHQ-4 and p-TMD, modified by gender (<i>p</i> = 0.016).</p>\\n </section>\\n \\n <section>\\n \\n <h3> Conclusions</h3>\\n \\n <p>High overall prevalence of p-TMD and overlapping primary headaches was found in young adults. In addition, the study reports gender-specific associations between p-TMD, psychological distress and physical comorbidities indicating that this association is stronger for men than for women.</p>\\n </section>\\n \\n <section>\\n \\n <h3> Significance Statement</h3>\\n \\n <p>This study found a higher-than-expected prevalence of painful temporomandibular disorders in young adults. It is based on a large population cohort and used standardised and validated screening tools. The study also reported common co-occurrence of primary headaches and explored gender differences. The study raises awareness for a possibly underestimated health burden in young individuals, particularly among individuals experiencing psychological distress and multiple physical symptoms.</p>\\n </section>\\n </div>\",\"PeriodicalId\":12021,\"journal\":{\"name\":\"European Journal of Pain\",\"volume\":\"29 5\",\"pages\":\"\"},\"PeriodicalIF\":3.5000,\"publicationDate\":\"2025-03-28\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://onlinelibrary.wiley.com/doi/epdf/10.1002/ejp.70013\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"European Journal of Pain\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://onlinelibrary.wiley.com/doi/10.1002/ejp.70013\",\"RegionNum\":2,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"ANESTHESIOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"European Journal of Pain","FirstCategoryId":"3","ListUrlMain":"https://onlinelibrary.wiley.com/doi/10.1002/ejp.70013","RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"ANESTHESIOLOGY","Score":null,"Total":0}
Prevalence of Painful Temporomandibular Disorders and Overlapping Primary Headaches Among Young Adults
Background
Large population-based estimates of the prevalence of painful temporomandibular disorders (p-TMD) utilising standardised screening tools are scarce and have not investigated the prevalence of overlapping primary headaches. We aimed to estimate the prevalence of p-TMD in a large population of young adults (18 to 23 years) and to estimate the co-occurrence of p-TMD and two primary headaches, migraine and tension-type headache (TTH). The study also aimed to examine the extent of psychological (PHQ-4) and physical (PHQ-15) comorbidities and report prevalence across three gender categories (women, men and other).
Methods
Survey data from the Danish National Birth Cohort were collected (n = 11,982), in a cross-sectional observational design. A sensitivity analysis was conducted to address participation bias, revealing minimal impact on the estimates.
Results
The overall prevalence of p-TMD was 26.4% with gender-specific prevalence of women: 31.5%, other: 39.2% and men: 16.8%. Among those with p-TMD, 80.5% reported headaches at least once a month, and 13.8% over 15 days monthly. For the p-TMD individuals with a medical headache diagnosis, 31.9% experienced TTH and 10.9% migraine. The study also identified a higher proportion of moderate/severe psychological distress and physical symptoms in the p-TMD group compared to the non-p-TMD group. Logistic regression revealed a positive association between PHQ-4 and p-TMD, modified by gender (p = 0.016).
Conclusions
High overall prevalence of p-TMD and overlapping primary headaches was found in young adults. In addition, the study reports gender-specific associations between p-TMD, psychological distress and physical comorbidities indicating that this association is stronger for men than for women.
Significance Statement
This study found a higher-than-expected prevalence of painful temporomandibular disorders in young adults. It is based on a large population cohort and used standardised and validated screening tools. The study also reported common co-occurrence of primary headaches and explored gender differences. The study raises awareness for a possibly underestimated health burden in young individuals, particularly among individuals experiencing psychological distress and multiple physical symptoms.
期刊介绍:
European Journal of Pain (EJP) publishes clinical and basic science research papers relevant to all aspects of pain and its management, including specialties such as anaesthesia, dentistry, neurology and neurosurgery, orthopaedics, palliative care, pharmacology, physiology, psychiatry, psychology and rehabilitation; socio-economic aspects of pain are also covered.
Regular sections in the journal are as follows:
• Editorials and Commentaries
• Position Papers and Guidelines
• Reviews
• Original Articles
• Letters
• Bookshelf
The journal particularly welcomes clinical trials, which are published on an occasional basis.
Research articles are published under the following subject headings:
• Neurobiology
• Neurology
• Experimental Pharmacology
• Clinical Pharmacology
• Psychology
• Behavioural Therapy
• Epidemiology
• Cancer Pain
• Acute Pain
• Clinical Trials.