2-羟基烷基取代有机磷酸官能化衍生物的氧烷基合成

IF 1.7 4区化学 Q3 CHEMISTRY, MULTIDISCIPLINARY

Russian Chemical Bulletin Pub Date : 2025-03-27 DOI:10.1007/s11172-025-4541-6

Yu. N. Bubnov, A. A. Prishchenko, M. V. Livantsov, O. P. Novikova, L. I. Livantsova, S. V. Baranin

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引用次数: 0

摘要

以三配位磷酸的三甲基硅基酯亲核加成为基础，制备了功能化2-羟基烷基取代有机磷及其衍生物。2-三甲基硅氧烷基取代膦酸盐是生产含氨基、羧基或亚砜基团的新型功能化2-羟基烷基取代有机磷的有效合成子。所得到的化合物是潜在的生物活性物质，有前途的萃取剂和多齿配体。

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Oxirane-based synthesis of functionalized derivatives of 2-hydroxyalkyl-substituted organophosphorus acids

Convenient syntheses of functionalized 2-hydroxyalkyl-substituted organophosphorus acids and their derivatives based on nucleophilic addition of trimethylsilyl esters of tricoordinated phosphorus acids to functionalized oxiranes have been developed. 2-Trimethylsiloxyalkyl-substituted phosphonites are effective synthons for the production of new functionalized 2-hydroxyalkyl-substituted organophosphorus acids bearing amino, carboxy or sulfo groups. The resulting compounds are of interest as potential bioactive substances, promising extractants and polydentate ligands.

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来源期刊

Russian Chemical Bulletin 化学-化学综合

CiteScore

2.70

自引率

47.10%

发文量

257

审稿时长

3-8 weeks

期刊介绍： Publishing nearly 500 original articles a year, by leading Scientists from Russia and throughout the world, Russian Chemical Bulletin is a prominent international journal. The coverage of the journal spans practically all areas of fundamental chemical research and is presented in five sections: General and Inorganic Chemistry; Physical Chemistry; Organic Chemistry; Organometallic Chemistry; Chemistry of Natural Compounds and Bioorganic Chemistry.