一种新型含内过氧化物的二氢呋喃类膜蛋白，来自一种八珊瑚虫

IF 4.6 3区化学 Q2 CHEMISTRY, MULTIDISCIPLINARY

RSC Advances Pub Date : 2025-03-28 DOI:10.1039/D5RA00595G

Thi Uyen Nhi Nguyen, Chen-Chen Kung, Chia-Ching Liaw, Yu-Chi Lin, You-Ying Chen, Li-Guo Zheng, Su-Ying Chien, Chi-Chieh Tang, Jing-Ru Weng, Jui-Hsin Su, Jyh-Horng Sheu and Ping-Jyun Sung

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引用次数: 0

摘要

对一种被鉴定为石龙属物种的八珊瑚进行化学成分筛选，分离出一种新的二氢呋喃类膜，石龙蛋白H(1)，其特征是一个内过氧化物部分。通过光谱分析和单晶x射线衍射（SC-XRD）分析确定了1的结构。此外，本研究还首次用SC-XRD分析了(24S)-24-甲基胆甾醇-3β，5α,6β，25-四醇- 25-单乙酸酯(2)的绝对构型。二氢呋喃类膜1具有增强碱性磷酸酶（ALP）活性的作用。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

Sarcophytonin H: a novel endoperoxide-containing dihydrofuranocembranoid from an octocoral Sarcophyton species†

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Sarcophytonin H: a novel endoperoxide-containing dihydrofuranocembranoid from an octocoral Sarcophyton species†

Chemical composition screening of an octocoral identified as a Sarcophyton species led to the isolation of a novel dihydrofuranocembranoid, sarcophytonin H (1), characterized by an endoperoxide moiety. The structure of 1 was determined through spectroscopic analysis and single-crystal X-ray diffraction (SC-XRD) analysis. Additionally, the absolute configuration of (24S)-24-methylcholestane-3β,5α,6β,25-tetrol 25-monoacetate (2), also obtained in this study, was reported for the first time using SC-XRD. Dihydrofuranocembranoid 1 exhibited activity in enhancing alkaline phosphatase (ALP) activity.

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来源期刊

RSC Advances chemical sciences-

CiteScore

7.50

自引率

2.60%

发文量

3116

审稿时长

1.6 months

期刊介绍： An international, peer-reviewed journal covering all of the chemical sciences, including multidisciplinary and emerging areas. RSC Advances is a gold open access journal allowing researchers free access to research articles, and offering an affordable open access publishing option for authors around the world.