妊娠期Mpox：揭示一种再次出现的疾病的母胎风险，一篇叙述性综述

IF 4.7 3区医学 Q1 INFECTIOUS DISEASES

Journal of Infection and Public Health Pub Date : 2025-03-13 DOI:10.1016/j.jiph.2025.102758

Benedetta Rossi , Giorgio Tiecco , Jacopo Logiudice , Roberta Gerami , Francesca Bertoni , Lina Rachele Tomasoni , Francesco Castelli , Eugenia Quiros-Roldan

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引用次数: 0

摘要

Mpox再次出现，特别是随着2024年Ib分支病毒的传播，最近的疫情引起了人们对其对孕妇影响的担忧。有限的数据表明，死产和流产等不良后果的风险增加，但对妊娠期m痘的了解仍然不完整。对文献进行了叙述性的回顾，重点是母胎传播和不同MPXV分支的含义。该病毒于2023年首次被发现，其传播加剧了人们对垂直传播的担忧，特别是在获得诊断工具和治疗的机会有限的非洲农村地区。考虑到Ib进化支的高传播率，垂直传播的风险已成为一个紧迫的问题。尽管数据有限，母胎传播已被记录，严重的胎儿结局，如死胎和积水胎儿。持续的研究和监测对于制定有效的临床指南和公共卫生干预措施至关重要，特别是在妊娠期管理m痘方面。

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Mpox in pregnancy: Unraveling the maternal-fetal risks of a re-emerging disease, a narrative review

Mpox has re-emerged, particularly with the spread of Clade Ib in 2024 and recent outbreaks have raised concerns about its impact on pregnant women. Limited data suggest increased risks of adverse outcomes such as stillbirths and miscarriages, but understanding of mpox in pregnancy remains incomplete. A narrative review of literature was conducted, focusing on maternal-fetal transmission and the implications of different MPXV clades. The spread of Clade Ib, first identified in 2023, has heightened concerns about vertical transmission, particularly in rural African regions where access to diagnostic tools and treatments is limited. The risk of vertical transmission has become a pressing concern, considering the high transmission rates of Clade Ib. Despite limited data, maternal-fetal transmission has been documented, with serious fetal outcomes such as stillbirths and hydrops fetalis. Continued research and surveillance are critical to developing effective clinical guidelines and public health interventions, especially for managing mpox in pregnancy.

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来源期刊

Journal of Infection and Public Health PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH -INFECTIOUS DISEASES

CiteScore

13.10

自引率

1.50%

发文量

203

审稿时长

96 days

期刊介绍： The Journal of Infection and Public Health, first official journal of the Saudi Arabian Ministry of National Guard Health Affairs, King Saud Bin Abdulaziz University for Health Sciences and the Saudi Association for Public Health, aims to be the foremost scientific, peer-reviewed journal encompassing infection prevention and control, microbiology, infectious diseases, public health and the application of healthcare epidemiology to the evaluation of health outcomes. The point of view of the journal is that infection and public health are closely intertwined and that advances in one area will have positive consequences on the other. The journal will be useful to all health professionals who are partners in the management of patients with communicable diseases, keeping them up to date. The journal is proud to have an international and diverse editorial board that will assist and facilitate the publication of articles that reflect a global view on infection control and public health, as well as emphasizing our focus on supporting the needs of public health practitioners. It is our aim to improve healthcare by reducing risk of infection and related adverse outcomes by critical review, selection, and dissemination of new and relevant information in the field of infection control, public health and infectious diseases in all healthcare settings and the community.