{"title":"目前对成人肾病综合征的认识：最小变化疾病。","authors":"Krishna Kumar Govindarajan","doi":"10.5527/wjn.v14.i1.101930","DOIUrl":null,"url":null,"abstract":"<p><p>The underlying molecular changes that result in minimal change disease (nephrotic syndrome) require an in-depth analysis. Current molecular studies have shown the involvement of zinc fingers and homeobox transcriptional factors in its pathogenesis. The application of therapeutic drugs relies on understanding the cascade of molecular events to determine their efficacy in managing the clinical condition.</p>","PeriodicalId":94272,"journal":{"name":"World journal of nephrology","volume":"14 1","pages":"101930"},"PeriodicalIF":0.0000,"publicationDate":"2025-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11755233/pdf/","citationCount":"0","resultStr":"{\"title\":\"Current understanding of adult nephrotic syndrome: Minimal change disease.\",\"authors\":\"Krishna Kumar Govindarajan\",\"doi\":\"10.5527/wjn.v14.i1.101930\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>The underlying molecular changes that result in minimal change disease (nephrotic syndrome) require an in-depth analysis. Current molecular studies have shown the involvement of zinc fingers and homeobox transcriptional factors in its pathogenesis. The application of therapeutic drugs relies on understanding the cascade of molecular events to determine their efficacy in managing the clinical condition.</p>\",\"PeriodicalId\":94272,\"journal\":{\"name\":\"World journal of nephrology\",\"volume\":\"14 1\",\"pages\":\"101930\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2025-03-25\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11755233/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"World journal of nephrology\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.5527/wjn.v14.i1.101930\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"World journal of nephrology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.5527/wjn.v14.i1.101930","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Current understanding of adult nephrotic syndrome: Minimal change disease.
The underlying molecular changes that result in minimal change disease (nephrotic syndrome) require an in-depth analysis. Current molecular studies have shown the involvement of zinc fingers and homeobox transcriptional factors in its pathogenesis. The application of therapeutic drugs relies on understanding the cascade of molecular events to determine their efficacy in managing the clinical condition.
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