Eric Mai, Eric Zhao, Jung K Mok, Junho Song, Patawut Bovonratwet, Tomoyuki Asada, Tejas Subramanian, Chad Z Simon, Joshua Zhang, Cole Kwas, William Doran, Evan Sheha, James Dowdell, Douglas S Wetmore, Sravisht Iyer, Sheeraz A Qureshi
{"title":"竖脊机脊柱平面阻滞与微创经椎间孔腰椎椎体间融合术后阿片类药物早期停药和恢复工作有关。","authors":"Eric Mai, Eric Zhao, Jung K Mok, Junho Song, Patawut Bovonratwet, Tomoyuki Asada, Tejas Subramanian, Chad Z Simon, Joshua Zhang, Cole Kwas, William Doran, Evan Sheha, James Dowdell, Douglas S Wetmore, Sravisht Iyer, Sheeraz A Qureshi","doi":"10.1097/BRS.0000000000005345","DOIUrl":null,"url":null,"abstract":"<p><strong>Study design/setting: </strong>Retrospective review of prospectively collected data.</p><p><strong>Objective: </strong>To assess the impact of erector spinae plane (ESP) blocks on recovery kinetics and patient-reported outcomes (PROMs) following minimally invasive transforaminal lumbar interbody fusion (MI-TLIF).</p><p><strong>Summary of background data: </strong>ESP block continues to emerge as a safe and effective regional anesthetic technique and has been shown to reduce immediate postoperative pain and opioid requirements, although its impact on patient recovery and outcomes farther out postoperatively remains unclear.</p><p><strong>Methods: </strong>Patients who underwent single-level MI-TLIF who did or did not receive ESP blocks performed by a single anesthesiologist were included. PROMs and MCID achievement rates for ODI, VAS-Back, VAS-Leg, and SF-12 PCS were determined within early (within 3 mo) and late (6 mo to 2 y) postoperative periods. Return-to-activities (RTA) metrics included driving, work, and discontinuation of opioids which were measured by days after surgery. Multivariable regression analyses were performed to determine factors associated with return-to-activities.</p><p><strong>Results: </strong>A total of 172 patients were included (mean age: 60.5 y, 46.5% female); 110 received ESP blocks and 62 did not. There were no differences in baseline characteristics between the cohorts. On univariate analysis, there were no differences in days to RTA between the cohorts. On multivariable analyses, ESP block was identified as a predictor for return-to-work by 30 days (OR 4.48, 95% CI [1.25-1.60], P=0.021), discontinuation of opioids by 15 days (OR: 2.40, 95% CI [1.08-5.35], P=0.032), and discontinuation of opioids by 30 days (OR: 5.57, 95% CI [1.87-16.56], P=0.002). There were no significant differences in change in PROM scores or MCID achievement rates between the cohorts.</p><p><strong>Conclusions: </strong>Our study demonstrated that ESP block administered prior to MI-TLIF may be associated with earlier return-to-work and discontinuation of opioids, while having limited impact on functional PROMs, MCID achievement rates, and GRC scores.</p>","PeriodicalId":22193,"journal":{"name":"Spine","volume":" ","pages":""},"PeriodicalIF":2.6000,"publicationDate":"2025-03-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Erector Spinae Plane Block is Associated with Earlier Discontinuation of Opioids and Return-to-Work Following Minimally Invasive Transforaminal Lumbar Interbody Fusion.\",\"authors\":\"Eric Mai, Eric Zhao, Jung K Mok, Junho Song, Patawut Bovonratwet, Tomoyuki Asada, Tejas Subramanian, Chad Z Simon, Joshua Zhang, Cole Kwas, William Doran, Evan Sheha, James Dowdell, Douglas S Wetmore, Sravisht Iyer, Sheeraz A Qureshi\",\"doi\":\"10.1097/BRS.0000000000005345\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Study design/setting: </strong>Retrospective review of prospectively collected data.</p><p><strong>Objective: </strong>To assess the impact of erector spinae plane (ESP) blocks on recovery kinetics and patient-reported outcomes (PROMs) following minimally invasive transforaminal lumbar interbody fusion (MI-TLIF).</p><p><strong>Summary of background data: </strong>ESP block continues to emerge as a safe and effective regional anesthetic technique and has been shown to reduce immediate postoperative pain and opioid requirements, although its impact on patient recovery and outcomes farther out postoperatively remains unclear.</p><p><strong>Methods: </strong>Patients who underwent single-level MI-TLIF who did or did not receive ESP blocks performed by a single anesthesiologist were included. PROMs and MCID achievement rates for ODI, VAS-Back, VAS-Leg, and SF-12 PCS were determined within early (within 3 mo) and late (6 mo to 2 y) postoperative periods. Return-to-activities (RTA) metrics included driving, work, and discontinuation of opioids which were measured by days after surgery. Multivariable regression analyses were performed to determine factors associated with return-to-activities.</p><p><strong>Results: </strong>A total of 172 patients were included (mean age: 60.5 y, 46.5% female); 110 received ESP blocks and 62 did not. There were no differences in baseline characteristics between the cohorts. On univariate analysis, there were no differences in days to RTA between the cohorts. On multivariable analyses, ESP block was identified as a predictor for return-to-work by 30 days (OR 4.48, 95% CI [1.25-1.60], P=0.021), discontinuation of opioids by 15 days (OR: 2.40, 95% CI [1.08-5.35], P=0.032), and discontinuation of opioids by 30 days (OR: 5.57, 95% CI [1.87-16.56], P=0.002). There were no significant differences in change in PROM scores or MCID achievement rates between the cohorts.</p><p><strong>Conclusions: </strong>Our study demonstrated that ESP block administered prior to MI-TLIF may be associated with earlier return-to-work and discontinuation of opioids, while having limited impact on functional PROMs, MCID achievement rates, and GRC scores.</p>\",\"PeriodicalId\":22193,\"journal\":{\"name\":\"Spine\",\"volume\":\" \",\"pages\":\"\"},\"PeriodicalIF\":2.6000,\"publicationDate\":\"2025-03-26\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Spine\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1097/BRS.0000000000005345\",\"RegionNum\":2,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"CLINICAL NEUROLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Spine","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1097/BRS.0000000000005345","RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"CLINICAL NEUROLOGY","Score":null,"Total":0}
引用次数: 0
摘要
研究设计/设置:对前瞻性收集的数据进行回顾性分析。目的:评估竖脊机脊柱平面(ESP)阻滞对微创经椎间孔腰椎椎体间融合术(MI-TLIF)术后恢复动力学和患者报告预后(PROMs)的影响。背景资料总结:ESP阻滞作为一种安全有效的区域麻醉技术不断出现,并已被证明可以减少术后立即疼痛和阿片类药物的需求,尽管其对患者恢复和术后预后的影响尚不清楚。方法:包括接受或未接受由单一麻醉师实施的ESP阻滞的单级MI-TLIF患者。在术后早期(3个月)和后期(6个月至2个月)测定ODI、VAS-Back、VAS-Leg和SF-12 PCS的prom和MCID成活率。恢复活动(RTA)指标包括驾驶、工作和阿片类药物停药,这些指标是在手术后几天测量的。进行多变量回归分析以确定与返工相关的因素。结果:共纳入172例患者(平均年龄60.5岁,女性46.5%);110人收到了ESP块,62人没有收到。各组间基线特征无差异。在单变量分析中,两组之间的RTA天数没有差异。在多变量分析中,ESP阻滞被确定为30天恢复工作(OR 4.48, 95% CI [1.25-1.60], P=0.021),阿片类药物停药15天(OR: 2.40, 95% CI [1.08-5.35], P=0.032)和阿片类药物停药30天(OR: 5.57, 95% CI [1.87-16.56], P=0.002)的预测因子。在队列之间,PROM分数或MCID完成率的变化没有显著差异。结论:我们的研究表明,在MI-TLIF之前施用ESP阻断可能与早期重返工作岗位和停止阿片类药物有关,而对功能性PROMs、MCID成分率和GRC评分的影响有限。
Erector Spinae Plane Block is Associated with Earlier Discontinuation of Opioids and Return-to-Work Following Minimally Invasive Transforaminal Lumbar Interbody Fusion.
Study design/setting: Retrospective review of prospectively collected data.
Objective: To assess the impact of erector spinae plane (ESP) blocks on recovery kinetics and patient-reported outcomes (PROMs) following minimally invasive transforaminal lumbar interbody fusion (MI-TLIF).
Summary of background data: ESP block continues to emerge as a safe and effective regional anesthetic technique and has been shown to reduce immediate postoperative pain and opioid requirements, although its impact on patient recovery and outcomes farther out postoperatively remains unclear.
Methods: Patients who underwent single-level MI-TLIF who did or did not receive ESP blocks performed by a single anesthesiologist were included. PROMs and MCID achievement rates for ODI, VAS-Back, VAS-Leg, and SF-12 PCS were determined within early (within 3 mo) and late (6 mo to 2 y) postoperative periods. Return-to-activities (RTA) metrics included driving, work, and discontinuation of opioids which were measured by days after surgery. Multivariable regression analyses were performed to determine factors associated with return-to-activities.
Results: A total of 172 patients were included (mean age: 60.5 y, 46.5% female); 110 received ESP blocks and 62 did not. There were no differences in baseline characteristics between the cohorts. On univariate analysis, there were no differences in days to RTA between the cohorts. On multivariable analyses, ESP block was identified as a predictor for return-to-work by 30 days (OR 4.48, 95% CI [1.25-1.60], P=0.021), discontinuation of opioids by 15 days (OR: 2.40, 95% CI [1.08-5.35], P=0.032), and discontinuation of opioids by 30 days (OR: 5.57, 95% CI [1.87-16.56], P=0.002). There were no significant differences in change in PROM scores or MCID achievement rates between the cohorts.
Conclusions: Our study demonstrated that ESP block administered prior to MI-TLIF may be associated with earlier return-to-work and discontinuation of opioids, while having limited impact on functional PROMs, MCID achievement rates, and GRC scores.
期刊介绍:
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Recognized internationally as the leading journal in its field, Spine is an international, peer-reviewed, bi-weekly periodical that considers for publication original articles in the field of Spine. It is the leading subspecialty journal for the treatment of spinal disorders. Only original papers are considered for publication with the understanding that they are contributed solely to Spine. The Journal does not publish articles reporting material that has been reported at length elsewhere.