{"title":"[»左束分支区域起搏«]。","authors":"Alice David, Amar Taha, Andreas Martinsson","doi":"","DOIUrl":null,"url":null,"abstract":"<p><p>Pacing-induced cardiomyopathy (PIC) is a condition that leads to increased morbidity and mortality. Unfortunately, it is not uncommon after implantation of a pacemaker with a right ventricular lead. Right ventricular pacing creates a delayed electrical activation, leading to dyssynchronous contraction, and it is a known risk factor for PIC. Left bundle branch area pacing (LBBAP) is a form of pacing that delivers a physiological activation of the left ventricle. The lead is implanted deep in the septum and captures the left bundle branch of the conduction system. This allows for a synchronous electrical activation of the ventricles. LBBAP has shorter ventricular activation time and less dyssynchronous contraction compared to right ventricular pacing. Recently, studies have shown that the long-term electrical parameters are comparable to right ventricular leads. Randomized trials are underway to compare LBBAP with right ventricular pacing and biventricular pacing.</p>","PeriodicalId":17988,"journal":{"name":"Lakartidningen","volume":"122 ","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2025-03-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"[»Left bundle branch area pacing«].\",\"authors\":\"Alice David, Amar Taha, Andreas Martinsson\",\"doi\":\"\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Pacing-induced cardiomyopathy (PIC) is a condition that leads to increased morbidity and mortality. Unfortunately, it is not uncommon after implantation of a pacemaker with a right ventricular lead. Right ventricular pacing creates a delayed electrical activation, leading to dyssynchronous contraction, and it is a known risk factor for PIC. Left bundle branch area pacing (LBBAP) is a form of pacing that delivers a physiological activation of the left ventricle. The lead is implanted deep in the septum and captures the left bundle branch of the conduction system. This allows for a synchronous electrical activation of the ventricles. LBBAP has shorter ventricular activation time and less dyssynchronous contraction compared to right ventricular pacing. Recently, studies have shown that the long-term electrical parameters are comparable to right ventricular leads. Randomized trials are underway to compare LBBAP with right ventricular pacing and biventricular pacing.</p>\",\"PeriodicalId\":17988,\"journal\":{\"name\":\"Lakartidningen\",\"volume\":\"122 \",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2025-03-12\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Lakartidningen\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Lakartidningen","FirstCategoryId":"1085","ListUrlMain":"","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Pacing-induced cardiomyopathy (PIC) is a condition that leads to increased morbidity and mortality. Unfortunately, it is not uncommon after implantation of a pacemaker with a right ventricular lead. Right ventricular pacing creates a delayed electrical activation, leading to dyssynchronous contraction, and it is a known risk factor for PIC. Left bundle branch area pacing (LBBAP) is a form of pacing that delivers a physiological activation of the left ventricle. The lead is implanted deep in the septum and captures the left bundle branch of the conduction system. This allows for a synchronous electrical activation of the ventricles. LBBAP has shorter ventricular activation time and less dyssynchronous contraction compared to right ventricular pacing. Recently, studies have shown that the long-term electrical parameters are comparable to right ventricular leads. Randomized trials are underway to compare LBBAP with right ventricular pacing and biventricular pacing.