胆囊切除术后罕见胆囊癌肝口转移的FNAC诊断。

IF 1 4区医学 Q4 MEDICAL LABORATORY TECHNOLOGY

Diagnostic Cytopathology Pub Date : 2025-03-26 DOI:10.1002/dc.25469

Arushi Gupta, Durre Aden, Sabina Khan, Nehal Ahmad

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引用次数: 0

摘要

背景：未经怀疑的胆囊癌（GBC）腹腔镜胆囊切除术（LC）后Port-site转移（PSM）是一种罕见的发生。细针抽吸细胞学是一种简单而省时的技术，因此它已被证明是诊断此类转移瘤的有用方法。病例报告：我们报告了一例45岁的女性，lc术后2年出现疼痛、多结节性上腹肿胀，最初是由于推测为良性胆石症。port部位肿胀的FNAC显示有恶性上皮细胞的高细胞涂片，因此诊断为低分化恶性肿瘤。随访影像学及组织病理学证实为偶发性原发性胆囊癌。讨论：胆囊癌港口转移预后差；因此，早期发现和干预至关重要。先进的成像和指导下的FNAC是早期诊断的关键工具，特别是在缺乏事先组织学检查的病例中。结论：本病例强调了胆囊切除术后警惕的术后监测和全面的组织病理学分析的关键作用，特别是在胆囊癌发病率较高的区域。FNAC对胆囊癌港口转移的早期发现和处理也具有重要的诊断价值。

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FNAC Diagnosis of Rare Port-Site Metastasis in Gallbladder Cancer Post-Cholecystectomy

Background

Port-site metastasis (PSM) following laparoscopic cholecystectomy (LC) for unsuspected gallbladder carcinoma (GBC) is a rare occurrence. Fine Needle Aspiration Cytology is a simple and time-saving technique, thus it has proven useful in diagnosing such metastases.

Case Report

We present a case of a 45-year-old female who developed painful, multinodular epigastric swellings 2 years post-LC, initially performed for presumed benign cholelithiasis. FNAC of the port-site swelling revealed hypercellular smears with malignant epithelial cells, leading to a diagnosis of poorly differentiated malignancy. Follow-up imaging and histopathology confirmed incidental primary gallbladder carcinoma.

Discussion

Port site metastasis in gallbladder carcinoma has a poor prognosis; thus, early detection and intervention are essential. Advanced imaging and FNAC under guidance serve as critical tools for early diagnosis, especially in cases lacking prior histological examination.

Conclusion

This case highlights the critical role of vigilant post-surgical monitoring and comprehensive histopathological analysis following cholecystectomy, especially in areas with a higher incidence of gallbladder carcinoma. FNAC also plays a valuable diagnostic modality for early detection and management of Port site metastasis in unsuspected gallbladder carcinoma cases.

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来源期刊

Diagnostic Cytopathology 医学-病理学

CiteScore

2.60

自引率

7.70%

发文量

163

审稿时长

3-6 weeks

期刊介绍： Diagnostic Cytopathology is intended to provide a forum for the exchange of information in the field of cytopathology, with special emphasis on the practical, clinical aspects of the discipline. The editors invite original scientific articles, as well as special review articles, feature articles, and letters to the editor, from laboratory professionals engaged in the practice of cytopathology. Manuscripts are accepted for publication on the basis of scientific merit, practical significance, and suitability for publication in a journal dedicated to this discipline. Original articles can be considered only with the understanding that they have never been published before and that they have not been submitted for simultaneous review to another publication.