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引用次数: 0
摘要
目的：甲状腺疾病与梅尼埃病（MD）之间的关系仍存在争议。本文旨在探讨甲状腺疾病与梅尼埃病之间的关系，并为预防和治疗梅尼埃病及其并发症提供新的证据：设计：系统综述和荟萃分析：方法：检索PubMed、EMBASE、Web of Science和Cochrane Library，检索期至2024年7月8日。根据资格标准筛选文献、提取数据并评估研究质量。探讨了甲状腺疾病中MD的患病率和/或发病率，以及甲状腺疾病中MD的患病率和/或发病率。采用随机效应模型计算了汇总比例及95%置信区间（CI）：最终有 18 项符合条件的研究入选。共有14项研究提到了甲状腺疾病在MD中的患病率，汇总患病率为8%。两项研究报告了甲状腺疾病患者中 MD 的患病率，汇总患病率为 22%。四项研究探讨了甲状腺疾病在MD中的发病率，总发病率为23%。甲状腺激素治疗不仅能改善甲减症状，还能改善MD：结论：甲状腺疾病与多发性硬化症之间存在明显的关联。结论：甲状腺疾病与多发性硬化症之间存在显著关联，甲状腺激素治疗可改善甲减和多发性硬化症的症状。现有证据有限，需要更多前瞻性的高质量研究来验证。
Association Between Ménière's Disease and Thyroid Disease: A Systematic Review and Meta-Analysis.
Objectives: The relationship between thyroid disease and Ménière's disease (MD) remains controversial. This article aims to explore the association between thyroid disease and MD and provide new evidence for the prevention and treatment of MD and its complications.
Design: A systematic review and meta-analysis.
Methods: PubMed, EMBASE, Web of Science and Cochrane Library were searched until July 08, 2024. Based on the eligibility criteria, the literature was screened, the data were extracted, and the study quality was evaluated. The prevalence and/or incidence of MD in thyroid disease and the prevalence and/or incidence of thyroid disease in MD were explored. The pooled proportion with 95% confidence interval (CI) was calculated using a random-effects model.
Results: Eighteen eligible studies were finally enrolled. A total of 14 studies mentioned the prevalence of thyroid disease in MD, with a pooled prevalence rate of 8%. Two studies reported the prevalence of MD in thyroid patients, with a pooled prevalence rate of 22%. Four studies explored the incidence of thyroid disease in MD, with a combined incidence rate of 23%. Thyroid hormone treatment not only improved hypothyroidism symptoms but also MD.
Conclusions: There is a significant association between thyroid disease and MD. Symptoms of hypothyroidism and MD can be improved after thyroid hormone treatment. The available evidence is limited, and more prospective and high-quality studies are required for validation.
期刊介绍：
Clinical Otolaryngology is a bimonthly journal devoted to clinically-oriented research papers of the highest scientific standards dealing with:
current otorhinolaryngological practice
audiology, otology, balance, rhinology, larynx, voice and paediatric ORL
head and neck oncology
head and neck plastic and reconstructive surgery
continuing medical education and ORL training
The emphasis is on high quality new work in the clinical field and on fresh, original research.
Each issue begins with an editorial expressing the personal opinions of an individual with a particular knowledge of a chosen subject. The main body of each issue is then devoted to original papers carrying important results for those working in the field. In addition, topical review articles are published discussing a particular subject in depth, including not only the opinions of the author but also any controversies surrounding the subject.
• Negative/null results
In order for research to advance, negative results, which often make a valuable contribution to the field, should be published. However, articles containing negative or null results are frequently not considered for publication or rejected by journals. We welcome papers of this kind, where appropriate and valid power calculations are included that give confidence that a negative result can be relied upon.
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