{"title":"用于曲马多环境检测的表面等离子体共振生物传感器。","authors":"Magdalena Čapková, Erika Hemmerová, Jiří Homola","doi":"10.1007/s00216-025-05832-0","DOIUrl":null,"url":null,"abstract":"<div><p>Contamination of surface water and drinking water with pharmaceuticals presents an environmental concern. It has been shown to affect aquatic organisms and have adverse health effects on humans. One of the most common pharmaceutical contaminants is the opioid analgesic tramadol. In this communication, we report on the first surface plasmon resonance biosensor-based detection of tramadol in water. The biosensor utilizes a binding inhibition format and enables detection of tramadol at a wide range of concentrations (5 orders of magnitude) with a limit of detection of 0.52 µg/L. The results of a small-scale environmental study are reported in which the biosensor was used to analyze river water samples. The results were found to agree well with those obtained using the liquid chromatography-tandem mass spectrometry (HPLC–MS/MS).</p><h3>Graphical abstract</h3>\n<div><figure><div><div><picture><source><img></source></picture></div></div></figure></div></div>","PeriodicalId":462,"journal":{"name":"Analytical and Bioanalytical Chemistry","volume":"417 13","pages":"2859 - 2865"},"PeriodicalIF":3.8000,"publicationDate":"2025-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Surface plasmon resonance biosensor for environmental detection of tramadol\",\"authors\":\"Magdalena Čapková, Erika Hemmerová, Jiří Homola\",\"doi\":\"10.1007/s00216-025-05832-0\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><p>Contamination of surface water and drinking water with pharmaceuticals presents an environmental concern. It has been shown to affect aquatic organisms and have adverse health effects on humans. One of the most common pharmaceutical contaminants is the opioid analgesic tramadol. In this communication, we report on the first surface plasmon resonance biosensor-based detection of tramadol in water. The biosensor utilizes a binding inhibition format and enables detection of tramadol at a wide range of concentrations (5 orders of magnitude) with a limit of detection of 0.52 µg/L. The results of a small-scale environmental study are reported in which the biosensor was used to analyze river water samples. The results were found to agree well with those obtained using the liquid chromatography-tandem mass spectrometry (HPLC–MS/MS).</p><h3>Graphical abstract</h3>\\n<div><figure><div><div><picture><source><img></source></picture></div></div></figure></div></div>\",\"PeriodicalId\":462,\"journal\":{\"name\":\"Analytical and Bioanalytical Chemistry\",\"volume\":\"417 13\",\"pages\":\"2859 - 2865\"},\"PeriodicalIF\":3.8000,\"publicationDate\":\"2025-03-25\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Analytical and Bioanalytical Chemistry\",\"FirstCategoryId\":\"92\",\"ListUrlMain\":\"https://link.springer.com/article/10.1007/s00216-025-05832-0\",\"RegionNum\":2,\"RegionCategory\":\"化学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"BIOCHEMICAL RESEARCH METHODS\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Analytical and Bioanalytical Chemistry","FirstCategoryId":"92","ListUrlMain":"https://link.springer.com/article/10.1007/s00216-025-05832-0","RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"BIOCHEMICAL RESEARCH METHODS","Score":null,"Total":0}
Surface plasmon resonance biosensor for environmental detection of tramadol
Contamination of surface water and drinking water with pharmaceuticals presents an environmental concern. It has been shown to affect aquatic organisms and have adverse health effects on humans. One of the most common pharmaceutical contaminants is the opioid analgesic tramadol. In this communication, we report on the first surface plasmon resonance biosensor-based detection of tramadol in water. The biosensor utilizes a binding inhibition format and enables detection of tramadol at a wide range of concentrations (5 orders of magnitude) with a limit of detection of 0.52 µg/L. The results of a small-scale environmental study are reported in which the biosensor was used to analyze river water samples. The results were found to agree well with those obtained using the liquid chromatography-tandem mass spectrometry (HPLC–MS/MS).
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Analytical and Bioanalytical Chemistry’s mission is the rapid publication of excellent and high-impact research articles on fundamental and applied topics of analytical and bioanalytical measurement science. Its scope is broad, and ranges from novel measurement platforms and their characterization to multidisciplinary approaches that effectively address important scientific problems. The Editors encourage submissions presenting innovative analytical research in concept, instrumentation, methods, and/or applications, including: mass spectrometry, spectroscopy, and electroanalysis; advanced separations; analytical strategies in “-omics” and imaging, bioanalysis, and sampling; miniaturized devices, medical diagnostics, sensors; analytical characterization of nano- and biomaterials; chemometrics and advanced data analysis.
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