热触发双乳液集成水凝胶微粒子用于多路分子诊断（Adv. Sci. 12/2025）

IF 14.1 1区材料科学 Q1 CHEMISTRY, MULTIDISCIPLINARY

Advanced Science Pub Date : 2025-03-27 DOI:10.1002/advs.202570083

Eui Ju Jeon, Seungwon Jung, Yoon-ha Jang, Seoyoung Lee, Song-Ee Choi, So Young Jeon, Lankyeong Yoon, Bong Kyun Kim, Tae Jong Kim, Kuenyoul Park, Seok Chung, Yong Shin, Sung-Han Kim, Heungsup Sung, Sang Kyung Kim

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引用次数: 0

摘要

在文章编号2408158中，Sang Kyung Kim， Seungwon Jung及其同事介绍了TaqPIN，一种用于多重分子诊断的水凝胶微粒平台。热响应性双乳液载体有效地将目标特异性试剂输送到每个微粒中，其中受限的扩增使独立的反应成为可能。TaqPIN集成到结构化阵列中，可实现高灵敏度、高特异性的SARS-CoV-2九联体变异检测。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

Thermally Triggered Double Emulsion-Integrated Hydrogel Microparticles for Multiplexed Molecular Diagnostics (Adv. Sci. 12/2025)

查看原文本刊更多论文

Thermally Triggered Double Emulsion-Integrated Hydrogel Microparticles for Multiplexed Molecular Diagnostics (Adv. Sci. 12/2025)

Double Emulsion-Integrated Hydrogel Microparticles

In article number 2408158, Sang Kyung Kim, Seungwon Jung, and co-workers introduce TaqPIN, a hydrogel microparticle platform for multiplexed molecular diagnostics. Thermo-responsive double emulsion carriers efficiently deliver target-specific reagents into each microparticle, where confined amplification enables independent reactions. Integrated into a structured array, TaqPIN achieves nine-plex SARS-CoV-2 variant detection with high sensitivity and specificity.

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来源期刊

Advanced Science CHEMISTRY, MULTIDISCIPLINARYNANOSCIENCE &-NANOSCIENCE & NANOTECHNOLOGY

CiteScore

18.90

自引率

2.60%

发文量

1602

审稿时长

1.9 months

期刊介绍： Advanced Science is a prestigious open access journal that focuses on interdisciplinary research in materials science, physics, chemistry, medical and life sciences, and engineering. The journal aims to promote cutting-edge research by employing a rigorous and impartial review process. It is committed to presenting research articles with the highest quality production standards, ensuring maximum accessibility of top scientific findings. With its vibrant and innovative publication platform, Advanced Science seeks to revolutionize the dissemination and organization of scientific knowledge.