甘德尔巴尔、查谟和克什米尔地区饮用水源中铀暴露的评估：生物动力学建模方法

IF 3.4 2区地球科学 Q1 GEOCHEMISTRY & GEOPHYSICS

Journal of Geochemical Exploration Pub Date : 2025-03-24 DOI:10.1016/j.gexplo.2025.107763

Mehak Mohi u Din , Salik Nazir , Shakeel Simnani , Mohammad Rafiq Chakan , Sajad Masood , Supriya Rani , Amit Kumar Singla

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引用次数: 0

摘要

为了回应人们对肾炎、骨结构潜在改变以及与饮用水中铀污染相关的致癌效应等潜在健康风险的担忧，在甘德尔巴尔、查谟和安布尔进行了一项全面研究；以解决人们对饮用水中铀污染可能对健康造成危害的关切。该研究量化了从不同来源收集的153个水样中的铀浓度。铀的浓度范围为0.51 ~ 6.83 μ L−1，平均浓度为1.15 μ L−1。计算了年龄和性别不同的年有效摄入剂量以及致癌和非致癌的健康风险。该研究使用Li的发室模型来分析铀在成人体内的生物动力学和毒性效应，特别关注铀在60年暴露期间的分布、目标器官的保留和铀的排泄。

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Assessment of uranium exposure in drinking water sources across Ganderbal, Jammu and Kashmir: A biokinetic modelling approach

In response to concerns regarding potential health risks like nephritis, potential alterations to bone structure, and carcinogenic effects associated with uranium contamination in drinking water, a comprehensive study was conducted across Ganderbal, Jammu & Kashmir to address concerns about potential health hazards associated with uranium contamination in drinking water. The study quantified uranium concentrations in 153 water samples collected from various sources. The uranium concentrations ranged from 0.51 to 6.83 μg L⁻¹, with an average concentration of 1.15 μg L⁻¹. The age and gender-specific annual effective ingestion doses were calculated along with carcinogenic and non-carcinogenic health risks. The study used Li's hair compartment model to analyze the biokinetics and toxic effects of uranium within the adult human body, particularly focusing on distribution, target organs for retention, and uranium excretion over a 60-year exposure period.

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来源期刊

Journal of Geochemical Exploration 地学-地球化学与地球物理

CiteScore

7.40

自引率

7.70%

发文量

148

审稿时长

8.1 months

期刊介绍： Journal of Geochemical Exploration is mostly dedicated to publication of original studies in exploration and environmental geochemistry and related topics. Contributions considered of prevalent interest for the journal include researches based on the application of innovative methods to: define the genesis and the evolution of mineral deposits including transfer of elements in large-scale mineralized areas. analyze complex systems at the boundaries between bio-geochemistry, metal transport and mineral accumulation. evaluate effects of historical mining activities on the surface environment. trace pollutant sources and define their fate and transport models in the near-surface and surface environments involving solid, fluid and aerial matrices. assess and quantify natural and technogenic radioactivity in the environment. determine geochemical anomalies and set baseline reference values using compositional data analysis, multivariate statistics and geo-spatial analysis. assess the impacts of anthropogenic contamination on ecosystems and human health at local and regional scale to prioritize and classify risks through deterministic and stochastic approaches. Papers dedicated to the presentation of newly developed methods in analytical geochemistry to be applied in the field or in laboratory are also within the topics of interest for the journal.