髋关节置换术后手术部位感染的危险因素：系统回顾和荟萃分析。

IF 3.9 3区医学 Q1 INFECTIOUS DISEASES

Journal of Hospital Infection Pub Date : 2025-03-22 DOI:10.1016/j.jhin.2025.02.021

B. Yang , Y. Lei , Y. Zeng , M. Luo , Z. Li , K. Lei , Y. Wang , Q. Xiao , J. Wen , W. Yan , H. Yan

{"title":"髋关节置换术后手术部位感染的危险因素：系统回顾和荟萃分析。","authors":"B. Yang , Y. Lei , Y. Zeng , M. Luo , Z. Li , K. Lei , Y. Wang , Q. Xiao , J. Wen , W. Yan , H. Yan","doi":"10.1016/j.jhin.2025.02.021","DOIUrl":null,"url":null,"abstract":"<div><div>A meta-analysis was conducted to determine the risk of infection following hip replacement and risk factors were identified for surgical site infection. PubMed/Medline, Embase and Cochrane Library databases were systematically searched, as well as the reference lists of previous systematic reviews and meta-analyses. The pooled odds ratio (OR) was estimated using a random effects model for each investigated factor. The evidence of observational studies was classified as high quality (class I), moderate quality (class II or III) or low quality (class IV) based on the GRADE system. A total of 25,383 potential articles met the inclusion criteria in the database search. After reviewing the titles, abstracts, and full texts, 27 articles were included in the final analysis, encompassing 699,473 patients who underwent hip arthroplasty. High-quality evidence shows that BMI (≥30 kg/m<sup>2</sup>) (OR 2.16; 95% CI 1.72–2.70), male sex (OR 1.39; 95% CI 1.26–1.53), operation time (≥120 min) (OR 1.72; 95% CI 1.39–2.14), American Society of Anesthesiologists (ASA) class ≥3 (OR 2.05; 95% CI 1.49–2.83), diabetes (OR 1.33; 95% CI 1.23–1.43), and heart disease (OR 1.99; 95% CI 1.48–2.68) are associated with a greater risk of infection. The meta-analysis revealed that age and renal disease were not associated with infection. In conclusion, this meta-analysis identified significant risk factors for infection after hip-replacement surgery, including BMI, male sex, operation time, heart disease, diabetes, and ASA class.</div></div>","PeriodicalId":54806,"journal":{"name":"Journal of Hospital Infection","volume":"160 ","pages":"Pages 60-73"},"PeriodicalIF":3.9000,"publicationDate":"2025-03-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Risk factors for infection in patients undergoing hip replacement: a systematic review and meta-analysis\",\"authors\":\"B. Yang , Y. Lei , Y. Zeng , M. Luo , Z. Li , K. Lei , Y. Wang , Q. Xiao , J. Wen , W. Yan , H. Yan\",\"doi\":\"10.1016/j.jhin.2025.02.021\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><div>A meta-analysis was conducted to determine the risk of infection following hip replacement and risk factors were identified for surgical site infection. PubMed/Medline, Embase and Cochrane Library databases were systematically searched, as well as the reference lists of previous systematic reviews and meta-analyses. The pooled odds ratio (OR) was estimated using a random effects model for each investigated factor. The evidence of observational studies was classified as high quality (class I), moderate quality (class II or III) or low quality (class IV) based on the GRADE system. A total of 25,383 potential articles met the inclusion criteria in the database search. After reviewing the titles, abstracts, and full texts, 27 articles were included in the final analysis, encompassing 699,473 patients who underwent hip arthroplasty. High-quality evidence shows that BMI (≥30 kg/m<sup>2</sup>) (OR 2.16; 95% CI 1.72–2.70), male sex (OR 1.39; 95% CI 1.26–1.53), operation time (≥120 min) (OR 1.72; 95% CI 1.39–2.14), American Society of Anesthesiologists (ASA) class ≥3 (OR 2.05; 95% CI 1.49–2.83), diabetes (OR 1.33; 95% CI 1.23–1.43), and heart disease (OR 1.99; 95% CI 1.48–2.68) are associated with a greater risk of infection. The meta-analysis revealed that age and renal disease were not associated with infection. In conclusion, this meta-analysis identified significant risk factors for infection after hip-replacement surgery, including BMI, male sex, operation time, heart disease, diabetes, and ASA class.</div></div>\",\"PeriodicalId\":54806,\"journal\":{\"name\":\"Journal of Hospital Infection\",\"volume\":\"160 \",\"pages\":\"Pages 60-73\"},\"PeriodicalIF\":3.9000,\"publicationDate\":\"2025-03-22\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of Hospital Infection\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S0195670125000623\",\"RegionNum\":3,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"INFECTIOUS DISEASES\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Hospital Infection","FirstCategoryId":"3","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0195670125000623","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"INFECTIOUS DISEASES","Score":null,"Total":0}

引用次数: 0

摘要

背景：我们进行了一项荟萃分析，以确定髋关节置换术后感染的风险，并确定手术部位感染的危险因素。方法：系统检索PubMed/Medline、Embase和Cochrane图书馆数据库，以及以往系统综述和meta分析的参考文献。使用随机效应模型估计每个被调查因素的合并优势比（OR）。根据GRADE系统，观察性研究的证据被分为高质量（I类）、中等质量（II或III类）或低质量（IV类）。结果：在数据库检索中，共有25,383篇潜在文章符合纳入标准。在回顾了标题、摘要和全文后，最终分析了27篇文章，包括699,473例接受髋关节置换术的患者。高质量证据表明，BMI(≥30 kg/m2) (OR 2.16；95% CI 1.72-2.70)，男性(OR 1.39；95% CI 1.26-1.53)、手术时间（≥120 min） (OR 1.72；95% CI 1.39-2.14)， ASA分级≥3级(OR 2.05；95% CI 1.49-2.83)，糖尿病(OR 1.33；95% CI 1.23-1.43)和心脏病(OR 1.99；95% CI 1.48-2.68)与感染风险较高相关。荟萃分析显示，年龄和肾脏疾病与感染无关。结论：本荟萃分析确定了髋关节置换术后感染的重要危险因素，包括BMI、男性性别、手术时间、心脏病、糖尿病和ASA分级。证据级别：IV级，III级和IV级研究的系统评价。试验注册号：审查方案已在PROSPERO注册。唯一识别码为“CRD42024535902”。超链接到特定的注册（必须公开访问，并将被检查）：“https://www.crd.york.ac.uk/prospero/display_record.php?RecordID=535902”。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

查看原文本刊更多论文

Risk factors for infection in patients undergoing hip replacement: a systematic review and meta-analysis

A meta-analysis was conducted to determine the risk of infection following hip replacement and risk factors were identified for surgical site infection. PubMed/Medline, Embase and Cochrane Library databases were systematically searched, as well as the reference lists of previous systematic reviews and meta-analyses. The pooled odds ratio (OR) was estimated using a random effects model for each investigated factor. The evidence of observational studies was classified as high quality (class I), moderate quality (class II or III) or low quality (class IV) based on the GRADE system. A total of 25,383 potential articles met the inclusion criteria in the database search. After reviewing the titles, abstracts, and full texts, 27 articles were included in the final analysis, encompassing 699,473 patients who underwent hip arthroplasty. High-quality evidence shows that BMI (≥30 kg/m²) (OR 2.16; 95% CI 1.72–2.70), male sex (OR 1.39; 95% CI 1.26–1.53), operation time (≥120 min) (OR 1.72; 95% CI 1.39–2.14), American Society of Anesthesiologists (ASA) class ≥3 (OR 2.05; 95% CI 1.49–2.83), diabetes (OR 1.33; 95% CI 1.23–1.43), and heart disease (OR 1.99; 95% CI 1.48–2.68) are associated with a greater risk of infection. The meta-analysis revealed that age and renal disease were not associated with infection. In conclusion, this meta-analysis identified significant risk factors for infection after hip-replacement surgery, including BMI, male sex, operation time, heart disease, diabetes, and ASA class.

求助全文

通过发布文献求助，成功后即可免费获取论文全文。去求助

来源期刊

Journal of Hospital Infection 医学-传染病学

CiteScore

12.70

自引率

5.80%

发文量

271

审稿时长

19 days

期刊介绍： The Journal of Hospital Infection is the editorially independent scientific publication of the Healthcare Infection Society. The aim of the Journal is to publish high quality research and information relating to infection prevention and control that is relevant to an international audience. The Journal welcomes submissions that relate to all aspects of infection prevention and control in healthcare settings. This includes submissions that: provide new insight into the epidemiology, surveillance, or prevention and control of healthcare-associated infections and antimicrobial resistance in healthcare settings; provide new insight into cleaning, disinfection and decontamination; provide new insight into the design of healthcare premises; describe novel aspects of outbreaks of infection; throw light on techniques for effective antimicrobial stewardship; describe novel techniques (laboratory-based or point of care) for the detection of infection or antimicrobial resistance in the healthcare setting, particularly if these can be used to facilitate infection prevention and control; improve understanding of the motivations of safe healthcare behaviour, or describe techniques for achieving behavioural and cultural change; improve understanding of the use of IT systems in infection surveillance and prevention and control.