结膜自体移植原发性翼状胬肉切除术的泪膜变化和干眼症状的术后结果

IF 2.1 4区 医学 Q2 OPHTHALMOLOGY
Naomi C Zatarain-Barrón, Guillermo Raul Vera-Duarte, Norma Morales Flores, Braulio Velasco-Sepulveda, Enrique O Graue-Hernandez, Arturo Ramirez-Miranda, Alejandro Navas
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引用次数: 0

摘要

目的确定接受原发性翼状胬肉切除术和结膜自体移植的患者泪膜特征和干眼症状的变化:进行了一项前瞻性、描述性和分析性研究。研究纳入了接受结膜自体移植手术切除的原发性翼状胬肉患者。在术前和术后 1 周、1 个月和 3 个月对眼表疾病指数(OSDI)测试、无创破裂时间(NIBUT)、脂质层干涉测量、泪液半月板高度和睑板腺脱落进行评估:31例患者的33只眼睛中,16只为右眼,20例为女性,平均年龄(51±9)岁。术前泪膜和干眼症状检查结果如下:OSDI试验为(36.34±22.04)秒,NIBUT为(8.30±1.17)秒,干涉测量为(53.03±32.32)纳米,泪液半月板高度为(29.90±10.01)毫米,上睑板腺脱落率为(24.78%±9.86%),下睑板腺脱落率为(22.57%±14.62%)。术后3个月时,OSDI评分明显降低至23.12分,泪半月板高度也明显降低至24.36分,最后一次就诊时上睑板腺脱落率(21.03%)和下睑板腺脱落率(15.06%)明显改善:结膜自体移植的原发性翼状胬肉切除术似乎有助于改善干眼症相关症状和泪膜特征,术后OSDI评分、泪液半月板高度和睑板腺脱落均有统计学意义上的显著变化。其他泪膜特征的客观评估变化并不明显。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Postoperative Outcomes Regarding Tear Film Changes and Dry Eye Symptoms in Primary Pterygium Excision With Conjunctival Autograft.

Objective: To determine changes in tear film characteristics and dry eye symptoms in patients who underwent primary pterygium excision with conjunctival autograft.

Methods: A prospective, descriptive, analytic study was performed. Patients with primary pterygium who underwent surgical excision with conjunctival autograft were included. Ocular surface disease index (OSDI) test, noninvasive break-up time (NIBUT), lipid layer interferometry, tear meniscus height, and meibomian gland dropout were evaluated preoperatively and at 1 week, 1 month, and 3 months postoperatively.

Results: Thirty-three eyes of 31 patients were included, 16 were right eyes, 20 patients were female, and with the average age of 51±9 years. The tear film and dry eye symptom findings before surgery were as follows: OSDI test 36.34±22.04, NIBUT 8.30±1.17 sec, interferometry 53.03±32.32 nm, tear meniscus height 29.90±10.01 mm, superior meibomian gland dropout 24.78%±9.86%, and inferior meibomian gland dropout 22.57%±14.62%. There was a significant decrease in the postop OSDI score to 23.12, as well as tear meniscus height to 24.36 at 3 months postop, and significant improvement in superior (21.03%) and inferior (15.06%) meibomian gland dropout in the final visit.

Conclusion: Primary pterygium excision with conjunctival autograft seems to help improve dry eye-related symptoms and tear film characteristics, with a statistically significant change in postop OSDI scores, tear meniscus height, and meibomian gland dropout. Changes in other objective evaluations of tear film characteristics were not as evident.

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来源期刊
CiteScore
4.50
自引率
4.30%
发文量
150
审稿时长
6-12 weeks
期刊介绍: Eye & Contact Lens: Science and Clinical Practice is the official journal of the Contact Lens Association of Ophthalmologists (CLAO), an international educational association for anterior segment research and clinical practice of interest to ophthalmologists, optometrists, and other vision care providers and researchers. Focusing especially on contact lenses, it also covers dry eye disease, MGD, infections, toxicity of drops and contact lens care solutions, topography, cornea surgery and post-operative care, optics, refractive surgery and corneal stability (eg, UV cross-linking). Peer-reviewed and published six times annually, it is a highly respected scientific journal in its field.
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