Sri Handayani, Radiyati Umi Partan, Zen Hafy, Fitri Octaviana, Diah Widiastuti
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The epilepsy group exhibited higher triglycerides, fasting blood sugar, and lower high density lipoprotein (HDL) values than the control group. The epilepsy group exhibited sedentary behaviour, while the control group had moderate to intense physical activity (plt;0.05). Epilepsy patients who take polytherapy, or several antiepileptic drugs, were 8.43 times more likely to develop metabolic syndrome (OR=8.43; 95%CI=1.45-32.12). Epilepsy patients with body mass index (BMI) >25 had 1.57 times the risk of metabolic syndrome (OR=1.57; 95%CI=1.16-2.34). Epilepsy patients with total cholesterol levels >200 mg/dL have a 5.81-fold higher risk of metabolic syndrome (OR=5.81; 95%CI=1.23-23.32).</p><p><strong>Conclusion: </strong>Our study found that more than a quarter of epilepsy patients have metabolic syndrome. 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引用次数: 0
摘要
目的:研究印度尼西亚巨港市穆罕默德·胡辛总医院癫痫患者代谢综合征与危险因素之间的关系。方法:于2023年7月至9月进行以医院为基础的病例对照研究。癫痫组102例,对照组102例。我们将数据收集方法分为三个阶段:问卷调查、人体测量和生化分析。结果:癫痫患者较对照组更易发生代谢综合征。癫痫组表现出比对照组更高的甘油三酯、空腹血糖和更低的高密度脂蛋白(HDL)值。癫痫组表现为久坐行为,而对照组则有中度至剧烈的身体活动(plt;0.05)。服用多种抗癫痫药物或多种抗癫痫药物的癫痫患者发生代谢综合征的可能性高出8.43倍(or =8.43;95% ci = 1.45 - -32.12)。体重指数(BMI)为bbb25的癫痫患者发生代谢综合征的风险为1.57倍(OR=1.57;95% ci = 1.16 - -2.34)。总胆固醇水平为bbb200 mg/dL的癫痫患者发生代谢综合征的风险高出5.81倍(OR=5.81;95% ci = 1.23 - -23.32)。结论:我们的研究发现超过四分之一的癫痫患者有代谢综合征。癫痫患者代谢综合征的主要危险因素是久坐不动的生活方式、几种抗癫痫药物、超重和总胆固醇水平升高。
Evaluation of risk factors for metabolic syndrome in epileptic patients in Palembang, Indonesia: a hospital-based and case-control study.
Aim: To examine the association between metabolic syndrome and risk factors in epileptic patients at Dr. Mohammad Hoesin General Hospital in Palembang, Indonesia.
Methods: A hospital-based comparative case control research was conducted from July to September 2023. A total of 102 patients in the epilepsy group and 102 in the control group participated in this study. We conducted the data collection approach in three stages: a questionnaire, anthropometric measures and biochemical analysis.
Results: Epilepsy patients were more likely to develop metabolic syndrome than the controls. The epilepsy group exhibited higher triglycerides, fasting blood sugar, and lower high density lipoprotein (HDL) values than the control group. The epilepsy group exhibited sedentary behaviour, while the control group had moderate to intense physical activity (plt;0.05). Epilepsy patients who take polytherapy, or several antiepileptic drugs, were 8.43 times more likely to develop metabolic syndrome (OR=8.43; 95%CI=1.45-32.12). Epilepsy patients with body mass index (BMI) >25 had 1.57 times the risk of metabolic syndrome (OR=1.57; 95%CI=1.16-2.34). Epilepsy patients with total cholesterol levels >200 mg/dL have a 5.81-fold higher risk of metabolic syndrome (OR=5.81; 95%CI=1.23-23.32).
Conclusion: Our study found that more than a quarter of epilepsy patients have metabolic syndrome. The main risk factors for metabolic syndrome in epilepsy patients were a sedentary lifestyle, several antiepileptic medications, overweight, and increased total cholesterol levels.
期刊介绍:
Medicinski Glasnik (MG) is the official publication (two times per year) of the Medical Association of Zenica-Doboj Canton. Manuscripts that present of original basic and applied research from all fields of medicine (general and clinical practice, and basic medical sciences) are invited.